JP7394059B2 - 抗寄生生物性ポアオン組成物 - Google Patents

抗寄生生物性ポアオン組成物 Download PDF

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Publication number
JP7394059B2
JP7394059B2 JP2020533625A JP2020533625A JP7394059B2 JP 7394059 B2 JP7394059 B2 JP 7394059B2 JP 2020533625 A JP2020533625 A JP 2020533625A JP 2020533625 A JP2020533625 A JP 2020533625A JP 7394059 B2 JP7394059 B2 JP 7394059B2
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composition
compositions
animal
pour
isoxazoline
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JP2020533625A
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English (en)
Japanese (ja)
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JP2021507891A (ja
Inventor
シーハン，ジョン・ジェラルド
フリーホーフ，キース
フロシュライ－シゴニヤルト，アニー
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インターベット インターナショナル ベー． フェー．
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Application filed by インターベット インターナショナル ベー． フェー． filed Critical インターベット インターナショナル ベー． フェー．
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Priority to JP2023132324A priority Critical patent/JP7627312B2/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/70—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
JP2020533625A 2017-12-21 2018-12-21 抗寄生生物性ポアオン組成物 Active JP7394059B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023132324A JP7627312B2 (ja) 2017-12-21 2023-08-15 抗寄生生物性ポアオン組成物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762608760P 2017-12-21 2017-12-21
US62/608,760 2017-12-21
PCT/EP2018/086558 WO2019122324A1 (en) 2017-12-21 2018-12-21 Antiparasitic pour-on compositions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023132324A Division JP7627312B2 (ja) 2017-12-21 2023-08-15 抗寄生生物性ポアオン組成物

Publications (2)

Publication Number Publication Date
JP2021507891A JP2021507891A (ja) 2021-02-25
JP7394059B2 true JP7394059B2 (ja) 2023-12-07

Family

ID=64949294

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020533625A Active JP7394059B2 (ja) 2017-12-21 2018-12-21 抗寄生生物性ポアオン組成物
JP2023132324A Active JP7627312B2 (ja) 2017-12-21 2023-08-15 抗寄生生物性ポアオン組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023132324A Active JP7627312B2 (ja) 2017-12-21 2023-08-15 抗寄生生物性ポアオン組成物

Country Status (9)

Country Link
US (1) US12390450B2 (cg-RX-API-DMAC7.html)
EP (2) EP3727375B1 (cg-RX-API-DMAC7.html)
JP (2) JP7394059B2 (cg-RX-API-DMAC7.html)
AR (1) AR113997A1 (cg-RX-API-DMAC7.html)
AU (2) AU2018386568B2 (cg-RX-API-DMAC7.html)
CA (1) CA3085896A1 (cg-RX-API-DMAC7.html)
ES (1) ES3018480T3 (cg-RX-API-DMAC7.html)
MX (2) MX2020006512A (cg-RX-API-DMAC7.html)
WO (1) WO2019122324A1 (cg-RX-API-DMAC7.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4076447B1 (en) * 2019-12-16 2024-01-17 Intervet International B.V. Parasite control in ruminants
EP4075981A1 (en) * 2019-12-16 2022-10-26 Intervet International B.V. Composition for lice control
US12655138B2 (en) 2020-07-24 2026-06-16 Elanco Us Inc. Process for making an isoxazoline compound and intermediate thereof
AU2021335500A1 (en) 2020-09-04 2023-05-04 Elanco Us Inc. Palatable formulations
EP4430947A1 (en) * 2023-03-17 2024-09-18 Przedsiebiorstwo Wielobranzowe "Vet-Agro" Sp. Z O.O. Therapeutic use of isoxazoline compounds, composition of isoxazoline compounds and kit for therapeutic use
CN117617236B (zh) * 2023-11-17 2026-05-19 中国农业大学 三唑类杀菌剂绿色乳油及其制备方法
WO2025191150A2 (en) 2024-03-15 2025-09-18 Krka, D.D., Novo Mesto Stable isoxazoline formulation for topical application to the skin
CN120053434B (zh) * 2025-02-28 2025-12-23 湖南尚成生物科技有限公司 一种弗雷拉纳滴剂及其制备方法
CN120531675A (zh) * 2025-06-11 2025-08-26 湖南尚成生物科技有限公司 一种氟雷拉纳莫昔克丁滴剂及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009156369A1 (en) 2008-06-24 2009-12-30 Intervet International B.V. Pharmaceutical transdermal compositions and method for treating inflammation in cattle
JP2014504586A (ja) 2010-12-27 2014-02-24 インターベツト・インターナシヨナル・ベー・ベー 経表面局所イソオキサゾリン製剤

Family Cites Families (22)

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BRPI0508140B1 (pt) 2004-03-05 2015-03-17 Nissan Chemical Ind Ltd Composto benzamida substituída por isoxazolina da fórmula (1); da fórmula (2) substituído por 3,5-bis (aril substituído); da fórmula (4) substituída por alquinibenzeno ou um sal do mesmo; "pesticida, agroquímico, inseticida, parasiticida contendo como ingrediente ativo um ou mais composto benzamida substituída por isoxazolina e sal do mesmo"
TWI412322B (zh) 2005-12-30 2013-10-21 杜邦股份有限公司 控制無脊椎害蟲之異唑啉
NZ580241A (en) 2007-04-10 2011-02-25 Bayer Cropscience Ag Insecticidal aryl isoxazoline derivatives
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
DK2182945T3 (en) 2007-06-27 2015-11-16 Du Pont PROCEDURE TO COMBAT PESTS WITH ANIMALS
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
BRPI0819849B8 (pt) * 2007-11-26 2021-05-25 Merial Ltd sistemas de solvente para formulações pour on para combater parasitas
TWI411395B (zh) 2007-12-24 2013-10-11 Syngenta Participations Ag 殺蟲化合物
ES2442342T3 (es) 2008-12-18 2014-02-11 Novartis Ag Derivados de las isoxazolinas y su uso como pesticida
AR074790A1 (es) 2008-12-19 2011-02-09 Novartis Ag Derivados de isooxazol sustituidos, composiciones farmaceuticas y para el control de parasitos que los comprenden y su uso en metodos para controlar parasitos en y sobre animales de sangre caliente.
PT3078664T (pt) 2009-12-17 2019-05-31 Boehringer Ingelheim Animal Health Usa Inc Composições antiparasitárias de di-hidroazoles
WO2011124998A1 (en) 2010-04-08 2011-10-13 Pfizer Inc. Substituted 3,5- di phenyl - isoxazoline derivatives as insecticides and acaricides
CN103260620A (zh) 2010-12-27 2013-08-21 英特维特国际股份有限公司 包含三缩四乙二醇的外用局部异噁唑啉制剂
WO2012155352A1 (en) 2011-05-19 2012-11-22 Eli Lilly And Company Dihydroisoxazole compounds, parasiticidal uses and formulations thereof
HUE042360T2 (hu) 2011-09-12 2019-06-28 Merial Inc Izoxazolin hatóanyagot tartalmazó parazitaellenes készítmények, ezek elõállítása és alkalmazása
CN108685894B (zh) 2012-04-04 2022-04-26 英特维特国际股份有限公司 软咀嚼药用产品
RS59297B1 (sr) 2012-09-07 2019-10-31 Zoetis Services Llc Paraziticidalne kombinacije spirocikličnog izoksazolina
CN114903848A (zh) * 2013-02-27 2022-08-16 阿根塔创新有限公司 透皮制剂
EP2999339B1 (en) 2013-05-20 2019-06-19 Zoetis Services LLC Long-acting spiro-isoxazoline antiparasitic compositions
MX374480B (es) 2013-09-30 2025-03-06 Zoetis Services Llc Formulaciones de espiro-isoxazolina de accion prolongada.
US9371293B2 (en) 2013-10-25 2016-06-21 Sumitomo Chemical Company, Limited Isoxazoline compound composition
WO2015066277A1 (en) 2013-11-01 2015-05-07 Merial Limited Antiparisitic and pesticidal isoxazoline compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009156369A1 (en) 2008-06-24 2009-12-30 Intervet International B.V. Pharmaceutical transdermal compositions and method for treating inflammation in cattle
JP2014504586A (ja) 2010-12-27 2014-02-24 インターベツト・インターナシヨナル・ベー・ベー 経表面局所イソオキサゾリン製剤

Also Published As

Publication number Publication date
MX2023010368A (es) 2023-09-12
JP7627312B2 (ja) 2025-02-05
RU2020123896A (ru) 2022-01-21
AU2024203397B2 (en) 2026-08-06
JP2023154054A (ja) 2023-10-18
EP3727375B1 (en) 2025-03-19
CA3085896A1 (en) 2019-06-27
JP2021507891A (ja) 2021-02-25
BR112020012465A2 (pt) 2020-11-24
AU2024203397A1 (en) 2024-06-06
US20200390748A1 (en) 2020-12-17
MX2020006512A (es) 2020-09-07
ES3018480T3 (es) 2025-05-16
AU2018386568A1 (en) 2020-06-11
EP4559482A3 (en) 2025-07-30
AU2018386568B2 (en) 2024-02-22
EP4559482A2 (en) 2025-05-28
US12390450B2 (en) 2025-08-19
WO2019122324A1 (en) 2019-06-27
EP3727375A1 (en) 2020-10-28
AR113997A1 (es) 2020-07-08

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