JP7389551B2 - Ｍｅｔエキソン１４欠失の検出と、関連する治療法 - Google Patents
Ｍｅｔエキソン１４欠失の検出と、関連する治療法 Download PDFInfo
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- JP7389551B2 JP7389551B2 JP2018559197A JP2018559197A JP7389551B2 JP 7389551 B2 JP7389551 B2 JP 7389551B2 JP 2018559197 A JP2018559197 A JP 2018559197A JP 2018559197 A JP2018559197 A JP 2018559197A JP 7389551 B2 JP7389551 B2 JP 7389551B2
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662336362P | 2016-05-13 | 2016-05-13 | |
| US62/336,362 | 2016-05-13 | ||
| PCT/EP2017/061310 WO2017194668A1 (en) | 2016-05-13 | 2017-05-11 | Detection of met exon 14 deletions and associated therapies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019520802A JP2019520802A (ja) | 2019-07-25 |
| JP2019520802A5 JP2019520802A5 (https=) | 2020-04-16 |
| JP7389551B2 true JP7389551B2 (ja) | 2023-11-30 |
Family
ID=58800788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018559197A Active JP7389551B2 (ja) | 2016-05-13 | 2017-05-11 | Ｍｅｔエキソン１４欠失の検出と、関連する治療法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11913072B2 (https=) |
| EP (1) | EP3455375B1 (https=) |
| JP (1) | JP7389551B2 (https=) |
| CN (1) | CN109072293A (https=) |
| CA (1) | CA3023839A1 (https=) |
| ES (1) | ES2978995T3 (https=) |
| WO (1) | WO2017194668A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119753091A (zh) | 2018-04-02 | 2025-04-04 | 格里尔公司 | 用于扩增与癌症相关联的cfDNA分子的化验板 |
| CN108929908A (zh) * | 2018-07-17 | 2018-12-04 | 张丽英 | 一种基于数字PCR平台c-MET基因Exon14跳读的检测方法 |
| IL281741B2 (en) | 2018-09-27 | 2026-04-01 | Grail Inc | Methylation markers and a targeted methylation detection panel |
| US20220259671A1 (en) * | 2019-08-28 | 2022-08-18 | An Hsu | Kit and methods to detect met gene fusion |
| US11211147B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing |
| US11475981B2 (en) | 2020-02-18 | 2022-10-18 | Tempus Labs, Inc. | Methods and systems for dynamic variant thresholding in a liquid biopsy assay |
| US11211144B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Methods and systems for refining copy number variation in a liquid biopsy assay |
| CN114107490B (zh) * | 2020-08-26 | 2024-06-21 | 北京仁诚神经肿瘤生物技术工程研究中心有限公司 | 评价患者对met抑制剂敏感性的试剂盒 |
| KR102616916B1 (ko) * | 2021-05-11 | 2023-12-21 | 주식회사 애이마 | 발암성 돌연변이 유전자 검출용 가이드 rna 내지 이의 용도 |
| CN116970686A (zh) * | 2023-05-23 | 2023-10-31 | 上海奕检医学检验实验室有限公司 | 基于QSEP检测c-MET基因14号外显子跳跃突变的检测方法 |
| CN117230204A (zh) * | 2023-11-15 | 2023-12-15 | 神州医疗科技股份有限公司 | 一种用于检测met基因14外显子剪接突变的引物探针组、试剂盒和检测系统 |
| TWI899908B (zh) * | 2024-03-22 | 2025-10-01 | 創行股份有限公司 | 癌症檢測套組及其應用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008520228A (ja) | 2004-11-24 | 2008-06-19 | セント ジョージズ エンタープライゼズ リミテッド | 前立腺癌の診断 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2491067A1 (en) * | 2004-12-24 | 2006-06-24 | Stichting Katholieke Universiteit | Mrna rations in urinary sediments and/or urine as a prognostic marker for prostate cancer |
| US8975019B2 (en) * | 2009-10-19 | 2015-03-10 | University Of Massachusetts | Deducing exon connectivity by RNA-templated DNA ligation/sequencing |
| WO2013049822A2 (en) * | 2011-10-01 | 2013-04-04 | Life Technologies Corporation | Diagnostic method for determining animals persistently infected (pi) with bovine viral diarrhea virus (bvdv) |
-
2017
- 2017-05-11 WO PCT/EP2017/061310 patent/WO2017194668A1/en not_active Ceased
- 2017-05-11 CN CN201780029236.XA patent/CN109072293A/zh active Pending
- 2017-05-11 ES ES17726561T patent/ES2978995T3/es active Active
- 2017-05-11 EP EP17726561.8A patent/EP3455375B1/en active Active
- 2017-05-11 CA CA3023839A patent/CA3023839A1/en active Pending
- 2017-05-11 US US15/592,475 patent/US11913072B2/en active Active
- 2017-05-11 JP JP2018559197A patent/JP7389551B2/ja active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008520228A (ja) | 2004-11-24 | 2008-06-19 | セント ジョージズ エンタープライゼズ リミテッド | 前立腺癌の診断 |
Non-Patent Citations (5)
| Title |
|---|
| Ｃｌｉｎｉｃａｌ Ｃａｎｃｅｒ Ｒｅｓｅａｒｃｈ，２０１６年，Ｖｏｌ．２２，Ｎｏ．４，ｐｐ．９１５－９２２ |
| ＪＯＵＲＮＡＬ ＯＦ ＣＬＩＮＩＣＡＬ ＯＮＣＯＬＯＧＹ，２０１６年 １月 ４日，３４（７），ｐｐ．７２１－７３０ |
| Ｊｏｕｒｎａｌ ｏｆ Ｃｌｉｎｉｃａｌ Ｐａｔｈｏｌｏｇｙ，２０１３年 ６月２５日，Ｖｏｌ．６６，ｐｐ．９８５－９９１ |
| Ｏｎｃｏｔａｒｇｅｔ，２０１５年 ９月１０日，６（２９），ｐｐ．２８２１１－２８２２２ |
| ＰＬＯＳ ＯＮＥ，２０１４年，Ｖｏｌ．９，Ｎｏ．１１，ｅ１１０７８０，ｐｐ．１－７ |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109072293A (zh) | 2018-12-21 |
| ES2978995T3 (es) | 2024-09-23 |
| EP3455375A1 (en) | 2019-03-20 |
| US20170327887A1 (en) | 2017-11-16 |
| CA3023839A1 (en) | 2017-11-16 |
| EP3455375B1 (en) | 2024-03-13 |
| JP2019520802A (ja) | 2019-07-25 |
| US11913072B2 (en) | 2024-02-27 |
| WO2017194668A1 (en) | 2017-11-16 |
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