JP7370870B2 - プールヒト血小板溶解物を調製するための方法、プールヒト血小板溶解物、及び神経障害を処置するためのその使用 - Google Patents

プールヒト血小板溶解物を調製するための方法、プールヒト血小板溶解物、及び神経障害を処置するためのその使用 Download PDF

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JP7370870B2
JP7370870B2 JP2019569741A JP2019569741A JP7370870B2 JP 7370870 B2 JP7370870 B2 JP 7370870B2 JP 2019569741 A JP2019569741 A JP 2019569741A JP 2019569741 A JP2019569741 A JP 2019569741A JP 7370870 B2 JP7370870 B2 JP 7370870B2
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phpl
treated
heat
pooled human
human platelet
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JP2020523398A5 (https=
JP2020523398A (ja
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ダヴィド・ドゥヴォス
ティエリー・ビュルヌーフ
ジャン－クリストフ・ドゥヴジャン
ミン－リ・チョウ
フロール・グエル
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Institut National de la Sante et de la Recherche Medicale INSERM
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0644—Platelets; Megakaryocytes

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP2019569741A 2017-06-16 2018-06-15 プールヒト血小板溶解物を調製するための方法、プールヒト血小板溶解物、及び神経障害を処置するためのその使用 Active JP7370870B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17305739 2017-06-16
EP17305739.9 2017-06-16
PCT/EP2018/066020 WO2018229278A1 (en) 2017-06-16 2018-06-15 Process for preparing a pooled human platelet lysate, pooled human platelet lysate and its use for treating neurological disorders

Publications (3)

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JP2020523398A JP2020523398A (ja) 2020-08-06
JP2020523398A5 JP2020523398A5 (https=) 2021-07-29
JP7370870B2 true JP7370870B2 (ja) 2023-10-30

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JP2019569741A Active JP7370870B2 (ja) 2017-06-16 2018-06-15 プールヒト血小板溶解物を調製するための方法、プールヒト血小板溶解物、及び神経障害を処置するためのその使用

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US (1) US11744863B2 (https=)
EP (1) EP3638263B1 (https=)
JP (1) JP7370870B2 (https=)
CN (1) CN110891582A (https=)
AU (1) AU2018284011B2 (https=)
BR (1) BR112019026846A2 (https=)
CA (1) CA3067294A1 (https=)
ES (1) ES2955282T3 (https=)
IL (1) IL271436B2 (https=)
WO (1) WO2018229278A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI744300B (zh) * 2016-03-23 2021-11-01 里爾中央醫學中心 改良性熱處理的血小板顆粒裂解液在製備用於治療神經系統疾病的組合物的用途
EP3920944A4 (en) * 2019-02-07 2023-03-29 Biobridge Global METHODS AND COMPOSITIONS RELATED TO PLATELET RELEASTAT AND PLATELET-RICH FIBRIN
EP3881858A1 (en) * 2020-03-20 2021-09-22 Rok Pangersic Heat-treated platelet-derived growth factor extract for use in a method of preventing or treating a tissue defect
WO2023103744A1 (zh) * 2021-12-07 2023-06-15 无限发展有限公司 血小板内生长因子的提取方法
EP4276173A1 (en) 2022-05-10 2023-11-15 Stemmatters, Biotecnologia e Medicina Regenerativa, S.A. Stable human platelet lysate composition, methods and uses thereof
AU2022489599A1 (en) * 2022-12-02 2025-07-17 Nuwacell Biotechnologies Co., Ltd. Culture medium, coating matrix and method for maturing midbrain dopaminergic progenitor cells
TWI909123B (zh) 2022-12-30 2025-12-21 思必瑞特生技股份有限公司 含血小板之組合物及其製備方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014522833A (ja) 2011-06-27 2014-09-08 エモリー ユニバーシティ 血小板溶解物の組成物、用途および調製
JP2016529283A (ja) 2013-08-27 2016-09-23 クック・ジェネラル・バイオテクノロジー・エルエルシー 濃厚血小板から誘導可能な生理活性組成物並びにその調製方法及び使用方法

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ES2006632A6 (es) 1987-04-21 1989-05-01 Green Cross Corp Procedimiento de tratamiento termico de fibrinogeno.
GB0512401D0 (en) * 2005-06-17 2005-07-27 Randox Lab Ltd Method
WO2008034803A1 (en) * 2006-09-18 2008-03-27 Medizinische Universität Graz Plasma-free platelet lysate for use as a supplement in cell cultures and for the preparation of cell therapeutics
EP2077118A1 (en) * 2008-01-07 2009-07-08 Gwo Rei Biomedical Technology Corp. Clottable concentrate of platelet growth factors and preparation method thereof
ES2402144T3 (es) * 2010-05-25 2013-04-29 Gwowei Technology Co., Ltd. Lisado plaquetario inactivado que contiene factores de crecimiento empobrecido en PDGF y VEGF y su procedimiento de preparación
IL210162A0 (en) 2010-12-21 2011-03-31 Omrix Biopharmaceuticals Viral inactivated platelet extract, use and preparation thereof
US20140176602A1 (en) 2011-08-18 2014-06-26 Nec Corporation Information processing system, information processing method, information processing apparatus, and control method and control program thereof
AU2013365623B2 (en) * 2012-12-20 2017-08-24 Omrix Biopharmaceuticals Ltd. Viral inactivated biological mixture

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014522833A (ja) 2011-06-27 2014-09-08 エモリー ユニバーシティ 血小板溶解物の組成物、用途および調製
JP2016529283A (ja) 2013-08-27 2016-09-23 クック・ジェネラル・バイオテクノロジー・エルエルシー 濃厚血小板から誘導可能な生理活性組成物並びにその調製方法及び使用方法

Non-Patent Citations (5)

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Title
BIOMATERIALS，2013年，34，7840-7850
CHOU ML.，Dedicated, virally-inactivated, platelet lysates and platelet microparticles in regenerative medicine and neuroprotective therapies，Human health and pathology. Universite du Droit et de la Sante - Lille II; Taipei medical university (Taipei)，2016年，https://tel.archives-ouvertes.fr/tel-01973786
FLORE GOUEL，THE PROTECTIVE EFFECT OF HUMAN PLATELET LYSATE IN MODELS OF NEURODEGENERATIVE 以下備考，JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE，米国，2016年，VOL:11，PAGE(S):3236 - 3240，https://pubmed.ncbi.nlm.nih.gov/27943621/，DISEASE: INVOLVEMENT OF THE AKT AND MEK PATHWAYS
Thrombosis and Haemostasis，2013年，Vol 110, No.2，323-330
YE CHIN CHOI; GREGORY M MORRIS; LEON SOKOLOFF，EFFECT OF PLATELET LYSATE ON GROWTH AND SULFATED GLYCOSAMINOGLYCAN SYNTHESIS IN ARTICULAR 以下備考，ARTHRITIS & RHEUMATISM，米国，1980年，VOL:23, NR:2，PAGE(S):220 - 224，http://dx.doi.org/10.1002/art.1780230213，CHONDROCYTE CULTURES

Also Published As

Publication number Publication date
US11744863B2 (en) 2023-09-05
US20200113942A1 (en) 2020-04-16
EP3638263A1 (en) 2020-04-22
ES2955282T3 (es) 2023-11-29
EP3638263C0 (en) 2023-08-23
RU2020101295A3 (https=) 2022-02-24
BR112019026846A2 (pt) 2020-06-30
CN110891582A (zh) 2020-03-17
AU2018284011B2 (en) 2024-05-30
IL271436B2 (en) 2024-02-01
JP2020523398A (ja) 2020-08-06
IL271436B1 (en) 2023-10-01
AU2018284011A1 (en) 2020-01-16
IL271436A (en) 2020-01-30
WO2018229278A1 (en) 2018-12-20
EP3638263B1 (en) 2023-08-23
RU2020101295A (ru) 2021-07-16
CA3067294A1 (en) 2018-12-20

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