CA3067294A1 - Process for preparing a pooled human platelet lysate, pooled human platelet lysate and its use for treating neurological disorders - Google Patents

Process for preparing a pooled human platelet lysate, pooled human platelet lysate and its use for treating neurological disorders Download PDF

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Publication number
CA3067294A1
CA3067294A1 CA3067294A CA3067294A CA3067294A1 CA 3067294 A1 CA3067294 A1 CA 3067294A1 CA 3067294 A CA3067294 A CA 3067294A CA 3067294 A CA3067294 A CA 3067294A CA 3067294 A1 CA3067294 A1 CA 3067294A1
Authority
CA
Canada
Prior art keywords
heat
pooled human
phpl
human platelet
platelet lysate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3067294A
Other languages
English (en)
French (fr)
Inventor
David DEVOS
Thierry Burnouf
Jean-christophe DEVEDJIAN
Ming-Li CHOU
Flore GOUEL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Centre Hospitalier Universitaire de Lille
Universite du Littoral Cote dOpale
Universite de Lille
Taipei Medical University TMU
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Centre Hospitalier Regional Universitaire de Lille CHRU
Universite du Littoral Cote dOpale
Universite de Lille
Taipei Medical University TMU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM, Centre Hospitalier Regional Universitaire de Lille CHRU, Universite du Littoral Cote dOpale, Universite de Lille, Taipei Medical University TMU filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Publication of CA3067294A1 publication Critical patent/CA3067294A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/19Platelets; Megacaryocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0085Brain, e.g. brain implants; Spinal cord
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0644Platelets; Megakaryocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA3067294A 2017-06-16 2018-06-15 Process for preparing a pooled human platelet lysate, pooled human platelet lysate and its use for treating neurological disorders Pending CA3067294A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17305739 2017-06-16
EP17305739.9 2017-06-16
PCT/EP2018/066020 WO2018229278A1 (en) 2017-06-16 2018-06-15 Process for preparing a pooled human platelet lysate, pooled human platelet lysate and its use for treating neurological disorders

Publications (1)

Publication Number Publication Date
CA3067294A1 true CA3067294A1 (en) 2018-12-20

Family

ID=59269973

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3067294A Pending CA3067294A1 (en) 2017-06-16 2018-06-15 Process for preparing a pooled human platelet lysate, pooled human platelet lysate and its use for treating neurological disorders

Country Status (10)

Country Link
US (1) US11744863B2 (https=)
EP (1) EP3638263B1 (https=)
JP (1) JP7370870B2 (https=)
CN (1) CN110891582A (https=)
AU (1) AU2018284011B2 (https=)
BR (1) BR112019026846A2 (https=)
CA (1) CA3067294A1 (https=)
ES (1) ES2955282T3 (https=)
IL (1) IL271436B2 (https=)
WO (1) WO2018229278A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI744300B (zh) * 2016-03-23 2021-11-01 里爾中央醫學中心 改良性熱處理的血小板顆粒裂解液在製備用於治療神經系統疾病的組合物的用途
JP2022519781A (ja) * 2019-02-07 2022-03-24 バイオブリッジ グローバル 血小板放出物および多血小板フィブリンに関する方法および組成物
EP3881858A1 (en) * 2020-03-20 2021-09-22 Rok Pangersic Heat-treated platelet-derived growth factor extract for use in a method of preventing or treating a tissue defect
WO2023103744A1 (zh) * 2021-12-07 2023-06-15 无限发展有限公司 血小板内生长因子的提取方法
EP4276173A1 (en) 2022-05-10 2023-11-15 Stemmatters, Biotecnologia e Medicina Regenerativa, S.A. Stable human platelet lysate composition, methods and uses thereof
KR20250108745A (ko) * 2022-12-02 2025-07-15 누와셀 바이오테크놀로지 코., 엘티디. 중뇌 도파민 작동성 전구 세포의 제조를 위한 배양 배지, 코팅 매트릭스 및 방법
TWI909123B (zh) 2022-12-30 2025-12-21 思必瑞特生技股份有限公司 含血小板之組合物及其製備方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2006632A6 (es) 1987-04-21 1989-05-01 Green Cross Corp Procedimiento de tratamiento termico de fibrinogeno.
GB0512401D0 (en) * 2005-06-17 2005-07-27 Randox Lab Ltd Method
WO2008034803A1 (en) * 2006-09-18 2008-03-27 Medizinische Universität Graz Plasma-free platelet lysate for use as a supplement in cell cultures and for the preparation of cell therapeutics
EP2077118A1 (en) * 2008-01-07 2009-07-08 Gwo Rei Biomedical Technology Corp. Clottable concentrate of platelet growth factors and preparation method thereof
EP2389942B1 (en) * 2010-05-25 2013-01-23 GwoWei Technology Co., Ltd. Virally-inactivated growth factors-containing platelet lysate depleted of PDGF and VEGF and preparation method thereof
IL210162A0 (en) 2010-12-21 2011-03-31 Omrix Biopharmaceuticals Viral inactivated platelet extract, use and preparation thereof
AU2012275562B2 (en) * 2011-06-27 2016-10-20 Children's Healthcare Of Atlanta, Inc. Compositions, uses, and preparation of platelet lysates
US20140176602A1 (en) 2011-08-18 2014-06-26 Nec Corporation Information processing system, information processing method, information processing apparatus, and control method and control program thereof
EP3848058A1 (en) * 2012-12-20 2021-07-14 Omrix Biopharmaceuticals Ltd. Viral inactivated biological mixture
CN114392274A (zh) * 2013-08-27 2022-04-26 库克通用生物技术有限责任公司 可来源于血小板浓缩液的生物活性组合物及其制备和使用方法

Also Published As

Publication number Publication date
RU2020101295A3 (https=) 2022-02-24
US11744863B2 (en) 2023-09-05
CN110891582A (zh) 2020-03-17
AU2018284011A1 (en) 2020-01-16
EP3638263C0 (en) 2023-08-23
BR112019026846A2 (pt) 2020-06-30
AU2018284011B2 (en) 2024-05-30
JP7370870B2 (ja) 2023-10-30
IL271436B2 (en) 2024-02-01
US20200113942A1 (en) 2020-04-16
ES2955282T3 (es) 2023-11-29
IL271436B1 (en) 2023-10-01
JP2020523398A (ja) 2020-08-06
EP3638263B1 (en) 2023-08-23
RU2020101295A (ru) 2021-07-16
EP3638263A1 (en) 2020-04-22
WO2018229278A1 (en) 2018-12-20
IL271436A (en) 2020-01-30

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