BR112019026846A2 - processo para preparar um lisado de plaquetas humanas agrupadas, lisado de plaquetas humanas agrupadas e seu uso para tratar transtornos neurológicos - Google Patents

processo para preparar um lisado de plaquetas humanas agrupadas, lisado de plaquetas humanas agrupadas e seu uso para tratar transtornos neurológicos Download PDF

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Publication number
BR112019026846A2
BR112019026846A2 BR112019026846-4A BR112019026846A BR112019026846A2 BR 112019026846 A2 BR112019026846 A2 BR 112019026846A2 BR 112019026846 A BR112019026846 A BR 112019026846A BR 112019026846 A2 BR112019026846 A2 BR 112019026846A2
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BR
Brazil
Prior art keywords
phpl
treatment
treated
fact
platelet lysate
Prior art date
Application number
BR112019026846-4A
Other languages
English (en)
Portuguese (pt)
Inventor
David DeVos
Thier­Ry Burnouf
Jean-Christophe Deved­Jian
Ming-Li Chou
Flore GOUEL
Original Assignee
INSERM (Institut National de la Santé et de la Recherche Médicale)
Centre Hospitalier Regional Et Universitaire De Lille (Chru)
Universite De Lille
Universite Du Littoral Cote D'opale
Taipei Medical University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INSERM (Institut National de la Santé et de la Recherche Médicale), Centre Hospitalier Regional Et Universitaire De Lille (Chru), Universite De Lille, Universite Du Littoral Cote D'opale, Taipei Medical University filed Critical INSERM (Institut National de la Santé et de la Recherche Médicale)
Publication of BR112019026846A2 publication Critical patent/BR112019026846A2/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0644—Platelets; Megakaryocytes

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BR112019026846-4A 2017-06-16 2018-06-15 processo para preparar um lisado de plaquetas humanas agrupadas, lisado de plaquetas humanas agrupadas e seu uso para tratar transtornos neurológicos BR112019026846A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17305739 2017-06-16
EP17305739.9 2017-06-16
PCT/EP2018/066020 WO2018229278A1 (en) 2017-06-16 2018-06-15 Process for preparing a pooled human platelet lysate, pooled human platelet lysate and its use for treating neurological disorders

Publications (1)

Publication Number Publication Date
BR112019026846A2 true BR112019026846A2 (pt) 2020-06-30

Family

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Family Applications (1)

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BR112019026846-4A BR112019026846A2 (pt) 2017-06-16 2018-06-15 processo para preparar um lisado de plaquetas humanas agrupadas, lisado de plaquetas humanas agrupadas e seu uso para tratar transtornos neurológicos

Country Status (10)

Country Link
US (1) US11744863B2 (https=)
EP (1) EP3638263B1 (https=)
JP (1) JP7370870B2 (https=)
CN (1) CN110891582A (https=)
AU (1) AU2018284011B2 (https=)
BR (1) BR112019026846A2 (https=)
CA (1) CA3067294A1 (https=)
ES (1) ES2955282T3 (https=)
IL (1) IL271436B2 (https=)
WO (1) WO2018229278A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI744300B (zh) * 2016-03-23 2021-11-01 里爾中央醫學中心 改良性熱處理的血小板顆粒裂解液在製備用於治療神經系統疾病的組合物的用途
JP2022519781A (ja) * 2019-02-07 2022-03-24 バイオブリッジ グローバル 血小板放出物および多血小板フィブリンに関する方法および組成物
EP3881858A1 (en) * 2020-03-20 2021-09-22 Rok Pangersic Heat-treated platelet-derived growth factor extract for use in a method of preventing or treating a tissue defect
WO2023103744A1 (zh) * 2021-12-07 2023-06-15 无限发展有限公司 血小板内生长因子的提取方法
EP4276173A1 (en) 2022-05-10 2023-11-15 Stemmatters, Biotecnologia e Medicina Regenerativa, S.A. Stable human platelet lysate composition, methods and uses thereof
KR20250108745A (ko) * 2022-12-02 2025-07-15 누와셀 바이오테크놀로지 코., 엘티디. 중뇌 도파민 작동성 전구 세포의 제조를 위한 배양 배지, 코팅 매트릭스 및 방법
TWI909123B (zh) 2022-12-30 2025-12-21 思必瑞特生技股份有限公司 含血小板之組合物及其製備方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2006632A6 (es) 1987-04-21 1989-05-01 Green Cross Corp Procedimiento de tratamiento termico de fibrinogeno.
GB0512401D0 (en) * 2005-06-17 2005-07-27 Randox Lab Ltd Method
WO2008034803A1 (en) * 2006-09-18 2008-03-27 Medizinische Universität Graz Plasma-free platelet lysate for use as a supplement in cell cultures and for the preparation of cell therapeutics
EP2077118A1 (en) * 2008-01-07 2009-07-08 Gwo Rei Biomedical Technology Corp. Clottable concentrate of platelet growth factors and preparation method thereof
EP2389942B1 (en) * 2010-05-25 2013-01-23 GwoWei Technology Co., Ltd. Virally-inactivated growth factors-containing platelet lysate depleted of PDGF and VEGF and preparation method thereof
IL210162A0 (en) 2010-12-21 2011-03-31 Omrix Biopharmaceuticals Viral inactivated platelet extract, use and preparation thereof
AU2012275562B2 (en) * 2011-06-27 2016-10-20 Children's Healthcare Of Atlanta, Inc. Compositions, uses, and preparation of platelet lysates
US20140176602A1 (en) 2011-08-18 2014-06-26 Nec Corporation Information processing system, information processing method, information processing apparatus, and control method and control program thereof
EP3848058A1 (en) * 2012-12-20 2021-07-14 Omrix Biopharmaceuticals Ltd. Viral inactivated biological mixture
CN114392274A (zh) * 2013-08-27 2022-04-26 库克通用生物技术有限责任公司 可来源于血小板浓缩液的生物活性组合物及其制备和使用方法

Also Published As

Publication number Publication date
RU2020101295A3 (https=) 2022-02-24
US11744863B2 (en) 2023-09-05
CN110891582A (zh) 2020-03-17
AU2018284011A1 (en) 2020-01-16
EP3638263C0 (en) 2023-08-23
CA3067294A1 (en) 2018-12-20
AU2018284011B2 (en) 2024-05-30
JP7370870B2 (ja) 2023-10-30
IL271436B2 (en) 2024-02-01
US20200113942A1 (en) 2020-04-16
ES2955282T3 (es) 2023-11-29
IL271436B1 (en) 2023-10-01
JP2020523398A (ja) 2020-08-06
EP3638263B1 (en) 2023-08-23
RU2020101295A (ru) 2021-07-16
EP3638263A1 (en) 2020-04-22
WO2018229278A1 (en) 2018-12-20
IL271436A (en) 2020-01-30

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Legal Events

Date Code Title Description
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]