JP2020523398A5 - - Google Patents
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- Publication number
- JP2020523398A5 JP2020523398A5 JP2019569741A JP2019569741A JP2020523398A5 JP 2020523398 A5 JP2020523398 A5 JP 2020523398A5 JP 2019569741 A JP2019569741 A JP 2019569741A JP 2019569741 A JP2019569741 A JP 2019569741A JP 2020523398 A5 JP2020523398 A5 JP 2020523398A5
- Authority
- JP
- Japan
- Prior art keywords
- treatment
- human platelet
- composition
- disorders
- phpl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000006166 lysate Substances 0.000 claims 13
- 238000000034 method Methods 0.000 claims 13
- 241000700605 Viruses Species 0.000 claims 5
- 238000010438 heat treatment Methods 0.000 claims 4
- 208000024827 Alzheimer disease Diseases 0.000 claims 3
- 102000008946 Fibrinogen Human genes 0.000 claims 3
- 108010049003 Fibrinogen Proteins 0.000 claims 3
- 208000018737 Parkinson disease Diseases 0.000 claims 3
- 229940012952 fibrinogen Drugs 0.000 claims 3
- 230000002779 inactivation Effects 0.000 claims 3
- 208000015122 neurodegenerative disease Diseases 0.000 claims 3
- 201000001119 neuropathy Diseases 0.000 claims 3
- 230000007823 neuropathy Effects 0.000 claims 3
- 208000033808 peripheral neuropathy Diseases 0.000 claims 3
- 201000011240 Frontotemporal dementia Diseases 0.000 claims 2
- 208000023105 Huntington disease Diseases 0.000 claims 2
- 206010064930 age-related macular degeneration Diseases 0.000 claims 2
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 238000001914 filtration Methods 0.000 claims 2
- 201000006417 multiple sclerosis Diseases 0.000 claims 2
- 239000004094 surface-active agent Substances 0.000 claims 2
- 208000014644 Brain disease Diseases 0.000 claims 1
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 claims 1
- 206010012289 Dementia Diseases 0.000 claims 1
- 206010021143 Hypoxia Diseases 0.000 claims 1
- 208000009829 Lewy Body Disease Diseases 0.000 claims 1
- 201000002832 Lewy body dementia Diseases 0.000 claims 1
- 208000012902 Nervous system disease Diseases 0.000 claims 1
- 208000029726 Neurodevelopmental disease Diseases 0.000 claims 1
- 208000036110 Neuroinflammatory disease Diseases 0.000 claims 1
- 208000025966 Neurological disease Diseases 0.000 claims 1
- 208000018642 Semantic dementia Diseases 0.000 claims 1
- 208000030886 Traumatic Brain injury Diseases 0.000 claims 1
- 238000010306 acid treatment Methods 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 claims 1
- 208000029028 brain injury Diseases 0.000 claims 1
- 238000005119 centrifugation Methods 0.000 claims 1
- 208000013677 cerebrovascular dementia Diseases 0.000 claims 1
- 230000007954 hypoxia Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 238000007914 intraventricular administration Methods 0.000 claims 1
- 201000010901 lateral sclerosis Diseases 0.000 claims 1
- 210000000265 leukocyte Anatomy 0.000 claims 1
- 208000002780 macular degeneration Diseases 0.000 claims 1
- 208000005264 motor neuron disease Diseases 0.000 claims 1
- 210000003205 muscle Anatomy 0.000 claims 1
- 208000017376 neurovascular disease Diseases 0.000 claims 1
- 238000009928 pasteurization Methods 0.000 claims 1
- 244000052769 pathogen Species 0.000 claims 1
- 230000001717 pathogenic effect Effects 0.000 claims 1
- 230000037361 pathway Effects 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 210000005241 right ventricle Anatomy 0.000 claims 1
- 238000007711 solidification Methods 0.000 claims 1
- 230000008023 solidification Effects 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 210000000211 third ventricle Anatomy 0.000 claims 1
- 230000009529 traumatic brain injury Effects 0.000 claims 1
- 230000002861 ventricular Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17305739 | 2017-06-16 | ||
| EP17305739.9 | 2017-06-16 | ||
| PCT/EP2018/066020 WO2018229278A1 (en) | 2017-06-16 | 2018-06-15 | Process for preparing a pooled human platelet lysate, pooled human platelet lysate and its use for treating neurological disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020523398A JP2020523398A (ja) | 2020-08-06 |
| JP2020523398A5 true JP2020523398A5 (https=) | 2021-07-29 |
| JP7370870B2 JP7370870B2 (ja) | 2023-10-30 |
Family
ID=59269973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019569741A Active JP7370870B2 (ja) | 2017-06-16 | 2018-06-15 | プールヒト血小板溶解物を調製するための方法、プールヒト血小板溶解物、及び神経障害を処置するためのその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11744863B2 (https=) |
| EP (1) | EP3638263B1 (https=) |
| JP (1) | JP7370870B2 (https=) |
| CN (1) | CN110891582A (https=) |
| AU (1) | AU2018284011B2 (https=) |
| BR (1) | BR112019026846A2 (https=) |
| CA (1) | CA3067294A1 (https=) |
| ES (1) | ES2955282T3 (https=) |
| IL (1) | IL271436B2 (https=) |
| WO (1) | WO2018229278A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI744300B (zh) * | 2016-03-23 | 2021-11-01 | 里爾中央醫學中心 | 改良性熱處理的血小板顆粒裂解液在製備用於治療神經系統疾病的組合物的用途 |
| EP3920944A4 (en) * | 2019-02-07 | 2023-03-29 | Biobridge Global | METHODS AND COMPOSITIONS RELATED TO PLATELET RELEASTAT AND PLATELET-RICH FIBRIN |
| EP3881858A1 (en) * | 2020-03-20 | 2021-09-22 | Rok Pangersic | Heat-treated platelet-derived growth factor extract for use in a method of preventing or treating a tissue defect |
| WO2023103744A1 (zh) * | 2021-12-07 | 2023-06-15 | 无限发展有限公司 | 血小板内生长因子的提取方法 |
| EP4276173A1 (en) | 2022-05-10 | 2023-11-15 | Stemmatters, Biotecnologia e Medicina Regenerativa, S.A. | Stable human platelet lysate composition, methods and uses thereof |
| AU2022489599A1 (en) * | 2022-12-02 | 2025-07-17 | Nuwacell Biotechnologies Co., Ltd. | Culture medium, coating matrix and method for maturing midbrain dopaminergic progenitor cells |
| TWI909123B (zh) | 2022-12-30 | 2025-12-21 | 思必瑞特生技股份有限公司 | 含血小板之組合物及其製備方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2006632A6 (es) | 1987-04-21 | 1989-05-01 | Green Cross Corp | Procedimiento de tratamiento termico de fibrinogeno. |
| GB0512401D0 (en) * | 2005-06-17 | 2005-07-27 | Randox Lab Ltd | Method |
| WO2008034803A1 (en) * | 2006-09-18 | 2008-03-27 | Medizinische Universität Graz | Plasma-free platelet lysate for use as a supplement in cell cultures and for the preparation of cell therapeutics |
| EP2077118A1 (en) * | 2008-01-07 | 2009-07-08 | Gwo Rei Biomedical Technology Corp. | Clottable concentrate of platelet growth factors and preparation method thereof |
| ES2402144T3 (es) * | 2010-05-25 | 2013-04-29 | Gwowei Technology Co., Ltd. | Lisado plaquetario inactivado que contiene factores de crecimiento empobrecido en PDGF y VEGF y su procedimiento de preparación |
| IL210162A0 (en) | 2010-12-21 | 2011-03-31 | Omrix Biopharmaceuticals | Viral inactivated platelet extract, use and preparation thereof |
| CA2840568C (en) | 2011-06-27 | 2021-05-04 | Emory University | Compositions, uses, and preparation of platelet lysates |
| US20140176602A1 (en) | 2011-08-18 | 2014-06-26 | Nec Corporation | Information processing system, information processing method, information processing apparatus, and control method and control program thereof |
| AU2013365623B2 (en) * | 2012-12-20 | 2017-08-24 | Omrix Biopharmaceuticals Ltd. | Viral inactivated biological mixture |
| WO2015031465A1 (en) | 2013-08-27 | 2015-03-05 | Cook General Biotechnology Llc | Bioactive compositions derivable from platelet concentrates, and methods for preparing and using same |
-
2018
- 2018-06-15 IL IL271436A patent/IL271436B2/en unknown
- 2018-06-15 EP EP18732057.7A patent/EP3638263B1/en active Active
- 2018-06-15 US US16/622,446 patent/US11744863B2/en active Active
- 2018-06-15 WO PCT/EP2018/066020 patent/WO2018229278A1/en not_active Ceased
- 2018-06-15 CA CA3067294A patent/CA3067294A1/en active Pending
- 2018-06-15 CN CN201880047062.4A patent/CN110891582A/zh active Pending
- 2018-06-15 ES ES18732057T patent/ES2955282T3/es active Active
- 2018-06-15 AU AU2018284011A patent/AU2018284011B2/en active Active
- 2018-06-15 BR BR112019026846-4A patent/BR112019026846A2/pt active Search and Examination
- 2018-06-15 JP JP2019569741A patent/JP7370870B2/ja active Active
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