JP7329056B2 - ペプチド並びにそれを含む細胞融合剤及びがん治療用医薬組成物 - Google Patents

ペプチド並びにそれを含む細胞融合剤及びがん治療用医薬組成物 Download PDF

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JP7329056B2
JP7329056B2 JP2021546983A JP2021546983A JP7329056B2 JP 7329056 B2 JP7329056 B2 JP 7329056B2 JP 2021546983 A JP2021546983 A JP 2021546983A JP 2021546983 A JP2021546983 A JP 2021546983A JP 7329056 B2 JP7329056 B2 JP 7329056B2
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amino acid
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acid sequence
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JPWO2021054448A1 (https=
JPWO2021054448A5 (https=
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美智子 甲賀
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2021546983A 2019-09-20 2020-09-18 ペプチド並びにそれを含む細胞融合剤及びがん治療用医薬組成物 Active JP7329056B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023127504A JP2023133582A (ja) 2019-09-20 2023-08-04 ペプチド並びにそれを含む細胞融合剤及びがん治療用医薬組成物

Applications Claiming Priority (3)

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JP2019171919 2019-09-20
JP2019171919 2019-09-20
PCT/JP2020/035491 WO2021054448A1 (ja) 2019-09-20 2020-09-18 ペプチド並びにそれを含む細胞融合剤及びがん治療用医薬組成物

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JP2023127504A Division JP2023133582A (ja) 2019-09-20 2023-08-04 ペプチド並びにそれを含む細胞融合剤及びがん治療用医薬組成物

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JPWO2021054448A1 JPWO2021054448A1 (https=) 2021-03-25
JPWO2021054448A5 JPWO2021054448A5 (https=) 2022-11-18
JP7329056B2 true JP7329056B2 (ja) 2023-08-17

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JP2021546983A Active JP7329056B2 (ja) 2019-09-20 2020-09-18 ペプチド並びにそれを含む細胞融合剤及びがん治療用医薬組成物
JP2023127504A Pending JP2023133582A (ja) 2019-09-20 2023-08-04 ペプチド並びにそれを含む細胞融合剤及びがん治療用医薬組成物

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JP2023127504A Pending JP2023133582A (ja) 2019-09-20 2023-08-04 ペプチド並びにそれを含む細胞融合剤及びがん治療用医薬組成物

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US (1) US20230034205A1 (https=)
EP (1) EP4032589A4 (https=)
JP (2) JP7329056B2 (https=)
KR (1) KR20220066309A (https=)
CN (1) CN114423778B (https=)
AU (1) AU2020349967A1 (https=)
CA (1) CA3158336A1 (https=)
WO (1) WO2021054448A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022202785A1 (ja) * 2021-03-22 2022-09-29 美智子 甲賀 ポリペプチド並びにそれを含む細胞融合剤及びがん治療用医薬組成物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008523829A (ja) 2004-12-22 2008-07-10 ノボザイムス アクティーゼルスカブ 血清アルブミンの組換え生成

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5768790A (en) * 1980-10-15 1982-04-27 Hidetoshi Tsuchida Cell fusion agent
DE3321226C2 (de) * 1983-06-11 1985-05-09 Kernforschungsanlage Jülich GmbH, 5170 Jülich Verfahren zur Fusion von Zellen
JP3099049B2 (ja) * 1992-07-29 2000-10-16 農林水産省果樹試験場長 電気的細胞融合及び電気的核酸導入のための大量処理用電極
EP1454988A1 (en) * 2003-03-03 2004-09-08 Institut National De La Sante Et De La Recherche Medicale (Inserm) Infectious flavivirus pseudo-particles containing functional prM-E envelope proteins
US20080176923A1 (en) * 2003-12-18 2008-07-24 Salama Zoser B Proline Derivatives Used as Pharmaceutical Active Ingredients for the Treatment of Tumors
EP2508606B1 (en) * 2006-10-24 2017-09-13 Momotaro-Gene Inc. Partial fragment of REIC/Dkk-3 gene and therapeutic agent for cancer containing the same
EP2323679A4 (en) * 2008-07-25 2012-08-22 Univ Colorado CLIP INHIBITORS AND METHODS FOR MODULATING IMMUNE FUNCTION
CN107201344A (zh) * 2017-06-13 2017-09-26 成都源泉生物科技有限公司 一种动物细胞融合基础培养基
CN108315319A (zh) * 2018-02-05 2018-07-24 翁炳焕 一种cd138单抗靶向捕获的细胞融合方法
CN108707600A (zh) * 2018-05-31 2018-10-26 东北农业大学 一种猪鼠细胞单细胞融合方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008523829A (ja) 2004-12-22 2008-07-10 ノボザイムス アクティーゼルスカブ 血清アルブミンの組換え生成

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
ALI, S.S. et al.,Phytophthora megakarya and Phytophthora palmivora, Closely Related Causal Agents of Cacao Black Pod,Genome Biol. Evol.,2017年,Vol.9, No.3,pp.536-557(pp.1-22)
HOOGENBOEZEM, E.N. and DUVALL, C.L.,Harnessing albumin as a carrier for cancer therapies,Adv. Drug Deliv. Rev.,2018年,Vol.130,pp.73-89
MAJOREK, K.A. et al.,Structural and immunologic characterization of bovine, horse, and rabbit serum albumins,Mol. Immunol.,2012年,Vol.52,pp.174-182
Phytophthora palmivora var. palmivora strain sbr112.9 scaffold_20380, whole genome shotgun sequence,GenBank accession no. NCKW01020374,2018年02月02日,[retrieved on 2020-10-12], Retrieved from the Internet, URL, https://www.ncbi.nlm.nih.gov/nuccore/NCKW01020374.1?report=girevhist
UENO, H. et al.,Epitope Mapping of Bovine Serum Albumin Using Monoclonal Antibodies Coupled with a Photoreactive Cro,J. Biochem.,1994年,Vol.115,pp.1119-1127
ZHAO, D. et al.,Preparation, characterization, and in vitro targeted delivery of folate-decorated paclitaxel-loaded,Int. J. Nanomedicine,2010年,Vol.5,pp.669-677

Also Published As

Publication number Publication date
EP4032589A4 (en) 2023-12-20
JPWO2021054448A1 (https=) 2021-03-25
JP2023133582A (ja) 2023-09-22
EP4032589A1 (en) 2022-07-27
KR20220066309A (ko) 2022-05-24
US20230034205A1 (en) 2023-02-02
CN114423778B (zh) 2024-05-24
WO2021054448A1 (ja) 2021-03-25
CN114423778A (zh) 2022-04-29
CA3158336A1 (en) 2021-03-25
AU2020349967A1 (en) 2022-05-12

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