CN114423778B - 肽及包含该肽的细胞融合剂以及用于癌症治疗的药物组合物 - Google Patents

肽及包含该肽的细胞融合剂以及用于癌症治疗的药物组合物 Download PDF

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Publication number
CN114423778B
CN114423778B CN202080065700.2A CN202080065700A CN114423778B CN 114423778 B CN114423778 B CN 114423778B CN 202080065700 A CN202080065700 A CN 202080065700A CN 114423778 B CN114423778 B CN 114423778B
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cells
peptide
cell fusion
polypeptide
amino acid
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CN114423778A (zh
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甲贺美智子
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN202080065700.2A 2019-09-20 2020-09-18 肽及包含该肽的细胞融合剂以及用于癌症治疗的药物组合物 Active CN114423778B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019171919 2019-09-20
JP2019-171919 2019-09-20
PCT/JP2020/035491 WO2021054448A1 (ja) 2019-09-20 2020-09-18 ペプチド並びにそれを含む細胞融合剤及びがん治療用医薬組成物

Publications (2)

Publication Number Publication Date
CN114423778A CN114423778A (zh) 2022-04-29
CN114423778B true CN114423778B (zh) 2024-05-24

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CN202080065700.2A Active CN114423778B (zh) 2019-09-20 2020-09-18 肽及包含该肽的细胞融合剂以及用于癌症治疗的药物组合物

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Country Link
US (1) US20230034205A1 (https=)
EP (1) EP4032589A4 (https=)
JP (2) JP7329056B2 (https=)
KR (1) KR20220066309A (https=)
CN (1) CN114423778B (https=)
AU (1) AU2020349967A1 (https=)
CA (1) CA3158336A1 (https=)
WO (1) WO2021054448A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022202785A1 (ja) * 2021-03-22 2022-09-29 美智子 甲賀 ポリペプチド並びにそれを含む細胞融合剤及びがん治療用医薬組成物

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0128567A2 (de) * 1983-06-11 1984-12-19 Forschungszentrum Jülich Gmbh Verfahren zur Fusion von Zellen
EP0594282A2 (en) * 1992-07-29 1994-04-27 Director General Of Fruit Tree Research Station Of Japan, Ministry Of Agriculture, Forestry And Fisheries Electrode for electrical cell fusion and electrical introduction of nucleic acids
WO2006066595A2 (en) * 2004-12-22 2006-06-29 Novozymes A/S Recombinant production of serum albumin
CN101541960A (zh) * 2006-10-24 2009-09-23 公文裕巳 REIC/Dkk-3基因的部分片段和包含所述部分片段的癌症治疗剂
CN107201344A (zh) * 2017-06-13 2017-09-26 成都源泉生物科技有限公司 一种动物细胞融合基础培养基
CN108315319A (zh) * 2018-02-05 2018-07-24 翁炳焕 一种cd138单抗靶向捕获的细胞融合方法
CN108707600A (zh) * 2018-05-31 2018-10-26 东北农业大学 一种猪鼠细胞单细胞融合方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5768790A (en) * 1980-10-15 1982-04-27 Hidetoshi Tsuchida Cell fusion agent
EP1454988A1 (en) * 2003-03-03 2004-09-08 Institut National De La Sante Et De La Recherche Medicale (Inserm) Infectious flavivirus pseudo-particles containing functional prM-E envelope proteins
US20080176923A1 (en) * 2003-12-18 2008-07-24 Salama Zoser B Proline Derivatives Used as Pharmaceutical Active Ingredients for the Treatment of Tumors
EP2323679A4 (en) * 2008-07-25 2012-08-22 Univ Colorado CLIP INHIBITORS AND METHODS FOR MODULATING IMMUNE FUNCTION

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0128567A2 (de) * 1983-06-11 1984-12-19 Forschungszentrum Jülich Gmbh Verfahren zur Fusion von Zellen
EP0594282A2 (en) * 1992-07-29 1994-04-27 Director General Of Fruit Tree Research Station Of Japan, Ministry Of Agriculture, Forestry And Fisheries Electrode for electrical cell fusion and electrical introduction of nucleic acids
WO2006066595A2 (en) * 2004-12-22 2006-06-29 Novozymes A/S Recombinant production of serum albumin
CN101541960A (zh) * 2006-10-24 2009-09-23 公文裕巳 REIC/Dkk-3基因的部分片段和包含所述部分片段的癌症治疗剂
CN107201344A (zh) * 2017-06-13 2017-09-26 成都源泉生物科技有限公司 一种动物细胞融合基础培养基
CN108315319A (zh) * 2018-02-05 2018-07-24 翁炳焕 一种cd138单抗靶向捕获的细胞融合方法
CN108707600A (zh) * 2018-05-31 2018-10-26 东北农业大学 一种猪鼠细胞单细胞融合方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Harnessing albumin as a carrier for cancer therapies;Ella N. Hoogenboezem et al.;Advanced Drug Delivery Reviews;第130卷;第73-89页 *
Structural and immunologic characterization of bovine, horse, and rabbit serum albumins;Karolina A. Majorek et al.;Molecular Immunology;第52卷;第174-182页 *
添加RGD短肽的新型培养基对细胞生长、融合及外源基因表达的影响;王佩佩 等;四川大学学报（医学版）;第49卷(第2期);第200-204页 *

Also Published As

Publication number Publication date
EP4032589A4 (en) 2023-12-20
JPWO2021054448A1 (https=) 2021-03-25
JP2023133582A (ja) 2023-09-22
JP7329056B2 (ja) 2023-08-17
EP4032589A1 (en) 2022-07-27
KR20220066309A (ko) 2022-05-24
US20230034205A1 (en) 2023-02-02
WO2021054448A1 (ja) 2021-03-25
CN114423778A (zh) 2022-04-29
CA3158336A1 (en) 2021-03-25
AU2020349967A1 (en) 2022-05-12

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