JP7323451B2 - フロルグルシノールおよびトリメチルフロログルシノールの医薬製剤 - Google Patents

フロルグルシノールおよびトリメチルフロログルシノールの医薬製剤 Download PDF

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JP7323451B2
JP7323451B2 JP2019543833A JP2019543833A JP7323451B2 JP 7323451 B2 JP7323451 B2 JP 7323451B2 JP 2019543833 A JP2019543833 A JP 2019543833A JP 2019543833 A JP2019543833 A JP 2019543833A JP 7323451 B2 JP7323451 B2 JP 7323451B2
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phloroglucinol
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trimethylphloroglucinol
release formulation
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JP2020510000A5 (enExample
JP2020510000A (ja
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パテル、ピユーシュ
ピアース、キャサリン
イサクソン、ジョナサン
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シンリックス ファーマ、エルエルシー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2019543833A 2017-03-08 2018-03-08 フロルグルシノールおよびトリメチルフロログルシノールの医薬製剤 Active JP7323451B2 (ja)

Priority Applications (1)

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JP2023085724A JP2023116518A (ja) 2017-03-08 2023-05-24 フロルグルシノールおよびトリメチルフロログルシノールの医薬製剤

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US201762468501P 2017-03-08 2017-03-08
US62/468,501 2017-03-08
PCT/US2018/021505 WO2018165404A1 (en) 2017-03-08 2018-03-08 Pharmaceutical formualtions of phloroglucinol and trimethylphloroglucinol

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JP2023085724A Division JP2023116518A (ja) 2017-03-08 2023-05-24 フロルグルシノールおよびトリメチルフロログルシノールの医薬製剤

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JP2020510000A JP2020510000A (ja) 2020-04-02
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JP7323451B2 true JP7323451B2 (ja) 2023-08-08

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JP2023085724A Pending JP2023116518A (ja) 2017-03-08 2023-05-24 フロルグルシノールおよびトリメチルフロログルシノールの医薬製剤

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US (2) US20200009076A1 (enExample)
EP (1) EP3592337B1 (enExample)
JP (2) JP7323451B2 (enExample)
KR (1) KR102636273B1 (enExample)
CN (1) CN110381925A (enExample)
AU (1) AU2018231044B2 (enExample)
CA (1) CA3053254C (enExample)
DK (1) DK3592337T3 (enExample)
EA (1) EA201992116A1 (enExample)
ES (1) ES2958616T3 (enExample)
WO (1) WO2018165404A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112535659B (zh) * 2019-09-20 2022-03-22 南京艾德凯腾生物医药有限责任公司 一种间苯三酚注射液的配制方法
CN115244028A (zh) 2019-12-20 2022-10-25 凯瑞康宁生物工程有限公司 4-缬氨酰氧基丁酸的合成方法
CN113750058B (zh) * 2020-06-01 2023-07-04 北京九能天远科技有限公司 一种间苯三酚冻干口崩片及其制备方法
AU2021293941B2 (en) 2020-06-18 2024-03-28 XWPharma Ltd. Pharmaceutical granulations of water-soluble active pharmaceutical ingredients
AU2021292406B2 (en) * 2020-06-18 2024-03-14 XWPharma Ltd. Controlled release granulations of water-soluble active pharmaceutical ingredients
EP4171520A1 (en) * 2020-06-26 2023-05-03 Bausch Health Ireland Limited Targeted release rifaximin compositions
CN116261451A (zh) 2020-07-24 2023-06-13 凯瑞康宁生物工程有限公司 γ-羟基丁酸衍生物的药物组合物和药物动力学
CN115666527B (zh) 2020-10-05 2025-03-07 凯瑞康宁生物工程有限公司 γ-羟基丁酸衍生物的修饰释放组合物
TW202300139A (zh) 2021-03-19 2023-01-01 凱瑞康寧生技股份有限公司 γ-羟基丁酸衍生物的聯合釋放製劑的藥代動力學
CN113304109A (zh) * 2021-06-08 2021-08-27 内蒙古大唐药业股份有限公司 一种醋柳黄酮固体脂质纳米粒分散液及其制备方法
CN115282132B (zh) * 2022-02-10 2024-01-30 郑州大学第一附属医院 用于缓解ercp胆道痉挛的复合物及其制备方法
AU2023292263A1 (en) * 2022-06-13 2024-12-12 Cinphloro Pharma, Llc Phloroglucinol formulations and methods of use

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002370968A (ja) 2001-06-12 2002-12-24 Towa Yakuhin Kk 薬物含有徐放性顆粒およびそれを含む錠剤
JP2009529524A (ja) 2006-03-10 2009-08-20 エイジーアイ・セラピューティクス・リサーチ・リミテッド 炎症性腸疾患を治療するための調節放出製剤と方法
JP2011525188A (ja) 2008-06-20 2011-09-15 ユーランド，インコーポレイテッド 徐放性骨格筋弛緩薬剤形の調製
WO2013087410A1 (fr) 2011-12-16 2013-06-20 Pharmeuro Traitement des crises de migraines, notamment d'algies vasculaires de la face
WO2014171542A1 (ja) 2013-04-19 2014-10-23 武田薬品工業株式会社 放出制御製剤
CN103494792B (zh) 2013-08-27 2015-03-04 寿光富康制药有限公司 一种复方间苯三酚冻干口腔崩解片及制备方法
JP2015143258A (ja) 2009-02-13 2015-08-06 ロマーク ラボラトリーズ エル．シー． ニタゾキサニドの制御放出医薬配合物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5773031A (en) 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
JP4563516B2 (ja) 1997-02-20 2010-10-13 マサチューセッツ インスティテュート オブ テクノロジー 迅速分散性を示す投与剤形、その使用法並びにその製造方法
SK180499A3 (en) * 1997-07-01 2001-08-06 Pfizer Sertraline salts and sustained-release dosage forms of sertraline
FR2772615B1 (fr) * 1997-12-23 2002-06-14 Lipha Comprime multicouche pour la liberation instantanee puis prolongee de substances actives
ITMI20020514A1 (it) 2002-03-12 2003-09-12 Jagotec Ag Sistema terapeutico per il rilascio controllato di uno o piu' principi attivi
DK1545475T3 (da) 2002-10-01 2014-07-28 Banner Pharmacaps Inc Enterisk sammensætning til fremstillingen af blød kapselvæg
US7387793B2 (en) 2003-11-14 2008-06-17 Eurand, Inc. Modified release dosage forms of skeletal muscle relaxants
US8846100B2 (en) 2006-05-12 2014-09-30 Shire Llc Controlled dose drug delivery system
JP5345620B2 (ja) 2007-08-15 2013-11-20 マクニール−ピーピーシー・インコーポレーテツド 即時放出及び徐放型イブプロフェンの投与法
CN102548544B (zh) * 2009-10-09 2015-01-21 永进药品工业株式会社 同时具有速效特性和长效特性的药物组合物
KR101320802B1 (ko) * 2010-02-16 2013-10-23 주식회사 드림파마 방출 제어형 사포그릴레이트 염산염 함유 다층 정제
GB201003731D0 (en) * 2010-03-05 2010-04-21 Univ Strathclyde Immediate/delayed drug delivery
HK1216513A1 (zh) 2013-03-15 2016-11-18 阿普雷奇亚制药有限责任公司 包含左乙拉西坦的快速分散劑型
KR101587142B1 (ko) * 2013-12-26 2016-01-21 한국유나이티드제약 주식회사 속방층과 2개의 서방층으로 이루어진 위장관 질환 치료용 모사프리드 구연산염 삼층정 서방제제
HUE047477T2 (hu) * 2015-06-04 2020-04-28 Pfizer Palbociclib szilárd dózisformái
KR101758451B1 (ko) * 2015-06-10 2017-07-27 대화제약 주식회사 안정성이 개선된 플로로글루시놀 무수물 함유 속용성 정제의 제조방법

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002370968A (ja) 2001-06-12 2002-12-24 Towa Yakuhin Kk 薬物含有徐放性顆粒およびそれを含む錠剤
JP2009529524A (ja) 2006-03-10 2009-08-20 エイジーアイ・セラピューティクス・リサーチ・リミテッド 炎症性腸疾患を治療するための調節放出製剤と方法
JP2011525188A (ja) 2008-06-20 2011-09-15 ユーランド，インコーポレイテッド 徐放性骨格筋弛緩薬剤形の調製
JP2015143258A (ja) 2009-02-13 2015-08-06 ロマーク ラボラトリーズ エル．シー． ニタゾキサニドの制御放出医薬配合物
WO2013087410A1 (fr) 2011-12-16 2013-06-20 Pharmeuro Traitement des crises de migraines, notamment d'algies vasculaires de la face
WO2014171542A1 (ja) 2013-04-19 2014-10-23 武田薬品工業株式会社 放出制御製剤
CN103494792B (zh) 2013-08-27 2015-03-04 寿光富康制药有限公司 一种复方间苯三酚冻干口腔崩解片及制备方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Expert Opin Ther Patents，2009年，19(6)，847-866
World J Gastroenterol，2014年，20(20)，6031-6043

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AU2018231044A1 (en) 2019-08-08
WO2018165404A1 (en) 2018-09-13
CA3053254C (en) 2024-02-20
KR102636273B1 (ko) 2024-02-16
AU2018231044B2 (en) 2023-04-06
WO2018165404A8 (en) 2019-09-12
DK3592337T3 (da) 2023-09-18
US20200009076A1 (en) 2020-01-09
JP2023116518A (ja) 2023-08-22
BR112019016091A2 (pt) 2020-04-14
EP3592337B1 (en) 2023-07-05
KR20190122218A (ko) 2019-10-29
ES2958616T3 (es) 2024-02-12
AU2018231044A8 (en) 2019-10-03
EA201992116A1 (ru) 2020-01-29
US20250177320A1 (en) 2025-06-05
CA3053254A1 (en) 2018-09-13
JP2020510000A (ja) 2020-04-02
CN110381925A (zh) 2019-10-25
EP3592337A1 (en) 2020-01-15

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