JP7321709B2 - がんの治療における使用のための免疫チェックポイント阻害剤と組み合わされたワクチン - Google Patents

がんの治療における使用のための免疫チェックポイント阻害剤と組み合わされたワクチン Download PDF

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JP7321709B2
JP7321709B2 JP2018563076A JP2018563076A JP7321709B2 JP 7321709 B2 JP7321709 B2 JP 7321709B2 JP 2018563076 A JP2018563076 A JP 2018563076A JP 2018563076 A JP2018563076 A JP 2018563076A JP 7321709 B2 JP7321709 B2 JP 7321709B2
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ガウダーナック,グスタフ
トルネス,アウドゥン
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ウルティモバックス エーエス
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001148Regulators of development
    • A61K39/00115Apoptosis related proteins, e.g. survivin or livin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • AHUMAN NECESSITIES
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    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • AHUMAN NECESSITIES
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    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • A61K2039/53DNA (RNA) vaccination
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    • A61K2039/70Multivalent vaccine
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    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2018563076A 2016-06-02 2017-06-02 がんの治療における使用のための免疫チェックポイント阻害剤と組み合わされたワクチン Active JP7321709B2 (ja)

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JP2022132995A JP2022171684A (ja) 2016-06-02 2022-08-24 がんの治療における使用のための免疫チェックポイント阻害剤と組み合わされたワクチン

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EP16172760 2016-06-02
EP16172760.7 2016-06-02
PCT/EP2017/063589 WO2017207814A1 (en) 2016-06-02 2017-06-02 A vaccine in combination with an immune checkpoint inhibitor for use in treating cancer

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JP2019517508A JP2019517508A (ja) 2019-06-24
JP2019517508A5 JP2019517508A5 (cg-RX-API-DMAC7.html) 2020-07-16
JP7321709B2 true JP7321709B2 (ja) 2023-08-07

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JP2022132995A Pending JP2022171684A (ja) 2016-06-02 2022-08-24 がんの治療における使用のための免疫チェックポイント阻害剤と組み合わされたワクチン

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CA (1) CA3026172A1 (cg-RX-API-DMAC7.html)
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US12251447B2 (en) 2018-06-29 2025-03-18 Taiho Pharmaceutical Co., Ltd. Combined formulation comprising four linked cytotoxic T lymphocyte (CTL) epitopes and a PD-1 pathway inhibitor and methods of use thereof to treat cancer
WO2022258794A2 (en) 2021-06-09 2022-12-15 Ultimovacs Ab A conjugate
WO2024083867A1 (en) 2022-10-17 2024-04-25 Ultimovacs Asa Biomarker
WO2024126758A2 (en) 2022-12-14 2024-06-20 Ultimovacs Ab A nucleic acid molecule and a chimeric polypeptide
WO2024126737A1 (en) 2022-12-14 2024-06-20 Ultimovacs Ab A core and a conjugate

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JP2019517508A (ja) 2019-06-24
WO2017207814A1 (en) 2017-12-07
ES2965957T3 (es) 2024-04-17
EP3463436A1 (en) 2019-04-10
FI3463436T3 (fi) 2023-12-04
RS65007B1 (sr) 2024-01-31
EP3463436B1 (en) 2023-09-20
SI3463436T1 (sl) 2024-02-29
US11419927B2 (en) 2022-08-23
JP2022171684A (ja) 2022-11-11
DK3463436T3 (da) 2023-12-18
HUE065176T2 (hu) 2024-05-28
AU2017275782B2 (en) 2024-08-15
EP4253419A3 (en) 2024-05-22
LT3463436T (lt) 2024-01-25
HRP20231650T1 (hr) 2024-05-10
US12168045B2 (en) 2024-12-17
CA3026172A1 (en) 2017-12-07
PL3463436T3 (pl) 2024-03-04
AU2017275782A1 (en) 2019-01-24
EP4253419A2 (en) 2023-10-04
US20230049012A1 (en) 2023-02-16
PT3463436T (pt) 2023-12-28
US20190247482A1 (en) 2019-08-15

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