JP7312169B2 - 遺伝性てんかん性障害の処置に使用するガナキソロン - Google Patents
遺伝性てんかん性障害の処置に使用するガナキソロン Download PDFInfo
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- JP7312169B2 JP7312169B2 JP2020526304A JP2020526304A JP7312169B2 JP 7312169 B2 JP7312169 B2 JP 7312169B2 JP 2020526304 A JP2020526304 A JP 2020526304A JP 2020526304 A JP2020526304 A JP 2020526304A JP 7312169 B2 JP7312169 B2 JP 7312169B2
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| CA2882708A1 (en) | 2012-08-21 | 2014-02-27 | Sage Therapeutics, Inc. | Methods of treating epilepsy or status epilepticus |
| SMT201800657T1 (it) | 2013-03-13 | 2019-01-11 | Sage Therapeutics Inc | Steroidi neuroattivi e loro metodi di utilizzo |
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| SI2986624T1 (sl) | 2013-04-17 | 2020-10-30 | Sage Therapeutics, Inc. | 19-nor nevroaktivni steroidi za metode zdravljenja |
| WO2014169836A1 (en) | 2013-04-17 | 2014-10-23 | Sage Therapeutics, Inc. | 19-nor neuroactive steroids and methods of use thereof |
| US9725481B2 (en) | 2013-04-17 | 2017-08-08 | Sage Therapeutics, Inc. | 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof |
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| WO2017156103A1 (en) | 2016-03-08 | 2017-09-14 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
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| CN114304068B (zh) * | 2020-09-30 | 2025-07-18 | 中国科学院脑科学与智能技术卓越创新中心 | 癫痫动物模型的制备及其应用 |
| WO2022125408A1 (en) * | 2020-12-07 | 2022-06-16 | Marinus Pharmaceuticals, Inc | Use of ganaxolone in treating an epilepsy disorder |
| US20230321116A1 (en) * | 2022-02-16 | 2023-10-12 | Lipocine Inc. | 3Alpha-OH-5Beta-Pregnan-20-One Compositions and Methods for Treating Central Nervous System Disorders |
| EP4412619A4 (en) | 2021-10-04 | 2025-11-12 | Marinus Pharmaceuticals Inc | GANAXOLONE FOR THE TREATMENT OF BOURNEVILLE'S TUBEROUS SCLEROSIS AND EPILEPTIC DISORDERS |
| WO2023060067A1 (en) * | 2021-10-04 | 2023-04-13 | Marinus Pharmaceuticals, Inc. | Amorphous solid dispersion ganaxolone formulation |
| CN119604281A (zh) * | 2022-06-02 | 2025-03-11 | 来普卡公司 | 治疗癫痫的方法和组合物 |
| WO2024257008A1 (en) * | 2023-06-13 | 2024-12-19 | Biostrike Unipessoal Lda | Compounds for diagnosing and treating epilepsy syndromes, methods and uses thereof |
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| US5556847A (en) * | 1994-10-27 | 1996-09-17 | Duquesne University Of The Holy Ghost | Methods of effecting memory enhancement mediated by steroid sulfatase inhibitors |
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| CA3060255A1 (en) * | 2017-04-18 | 2018-10-25 | Marinus Pharmaceuticals, Inc | Sustained release injectable neurosteroid formulations |
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| JP2015527371A (ja) | 2012-08-21 | 2015-09-17 | セージ セラピューティクス， インコーポレイテッド | てんかんまたはてんかん重積状態の処置方法 |
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| AU2018364659A1 (en) | 2020-05-28 |
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| EP3706755A1 (en) | 2020-09-16 |
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| US20190160078A1 (en) | 2019-05-30 |
| EA202091144A1 (ru) | 2020-09-16 |
| CA3079259A1 (en) | 2019-05-16 |
| JP2023153783A (ja) | 2023-10-18 |
| SG10202110563YA (en) | 2021-11-29 |
| AU2024227357A1 (en) | 2024-10-31 |
| US20250082651A1 (en) | 2025-03-13 |
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