JP7297272B2 - 細胞製造装置 - Google Patents

細胞製造装置 Download PDF

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Publication number
JP7297272B2
JP7297272B2 JP2021542014A JP2021542014A JP7297272B2 JP 7297272 B2 JP7297272 B2 JP 7297272B2 JP 2021542014 A JP2021542014 A JP 2021542014A JP 2021542014 A JP2021542014 A JP 2021542014A JP 7297272 B2 JP7297272 B2 JP 7297272B2
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cell
culture tank
culture
medium
plate
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Japanese (ja)
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JPWO2021038997A1 (https=
JPWO2021038997A5 (https=
Inventor
一訓 伴
聡 木下
剛士 田邊
亮二 平出
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Fanuc Corp
I Peace Inc
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Fanuc Corp
I Peace Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/42—Integrated assemblies, e.g. cassettes or cartridges
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/40—Manifolds; Distribution pieces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/06—Plates; Walls; Drawers; Multilayer plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/16—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature by recirculation of culture medium at controlled temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/22—Heat exchange systems, e.g. heat jackets or outer envelopes in contact with the bioreactor walls
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/06—Hydrolysis; Cell lysis; Extraction of intracellular or cell wall material

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2021542014A 2019-08-29 2020-05-28 細胞製造装置 Active JP7297272B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962893578P 2019-08-29 2019-08-29
US62/893,578 2019-08-29
PCT/JP2020/021241 WO2021038997A1 (ja) 2019-08-29 2020-05-28 細胞製造装置

Publications (3)

Publication Number Publication Date
JPWO2021038997A1 JPWO2021038997A1 (https=) 2021-03-04
JPWO2021038997A5 JPWO2021038997A5 (https=) 2022-05-10
JP7297272B2 true JP7297272B2 (ja) 2023-06-26

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ID=74685411

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JP2021542014A Active JP7297272B2 (ja) 2019-08-29 2020-05-28 細胞製造装置

Country Status (5)

Country Link
US (1) US20220356436A1 (https=)
EP (1) EP4023746A4 (https=)
JP (1) JP7297272B2 (https=)
CN (1) CN114341337A (https=)
WO (1) WO2021038997A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020262351A1 (ja) * 2019-06-28 2020-12-30 アイ ピース， インコーポレイテッド 細胞塊分割器、細胞塊分割器の製造方法、及び細胞塊の分割方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000270837A (ja) 1999-03-25 2000-10-03 Sanyo Electric Co Ltd インキュベータ
JP2005333912A (ja) 2004-05-28 2005-12-08 Yamaha Corp 小型培養観察装置
JP2012506257A (ja) 2008-10-22 2012-03-15 バイオベスト インターナショナル インコーポレイテッド 細胞および細胞由来生成物の産生のための、灌流バイオリアクター、細胞培養システム、および方法
WO2016093321A1 (ja) 2014-12-11 2016-06-16 株式会社アイカムス・ラボ 細胞培養方法及び細胞培養装置
WO2017038887A1 (ja) 2015-08-31 2017-03-09 アイ・ピース株式会社 多能性幹細胞製造システム

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002315566A (ja) 2001-04-24 2002-10-29 Takagi Ind Co Ltd 細胞・組織培養装置
WO2003087292A2 (en) * 2002-04-08 2003-10-23 Millenium Biologix Inc. Automated tissue engineering system
WO2006037022A2 (en) * 2004-09-24 2006-04-06 Massachusetts Institute Of Technology Microbioreactor for continuous cell culture
KR20080072022A (ko) 2005-11-01 2008-08-05 가부시키가이샤 메디넷 세포배양장치, 세포배양방법, 세포배양프로그램, 및세포배양시스템
US8048999B2 (en) 2005-12-13 2011-11-01 Kyoto University Nuclear reprogramming factor
JP2008259430A (ja) * 2007-04-10 2008-10-30 Tokai Hit:Kk 顕微鏡観察用培養器
JP2010142196A (ja) * 2008-12-22 2010-07-01 Sanyo Electric Co Ltd 細胞培養装置及び細胞培養カセット
CA2863050C (en) * 2012-01-13 2022-10-04 Ge Healthcare Bio-Sciences Corp. Biological reactor comprising a single use flexible container and heat exchange module
WO2014049701A1 (ja) 2012-09-26 2014-04-03 株式会社日立製作所 細胞培養容器およびそれを用いた細胞培養装置
DE102013114634A1 (de) * 2013-12-20 2015-06-25 Karlsruher Institut für Technologie Mikrofluidischer Bioreaktor mit modularem Aufbau zur Synthese von Zellmetaboliten, das Verfahren zur Nutzung sowie dessen Verwendung
EP3286731B1 (en) * 2015-04-23 2020-09-16 BD Kiestra B.V. Colony contrast gathering
CN108779421B (zh) * 2016-03-08 2022-04-19 国立研究开发法人产业技术综合研究所 细胞培养装置以及细胞培养方法
JP6202505B1 (ja) 2016-06-17 2017-09-27 株式会社アイカムス・ラボ 細胞培養装置
US11259520B2 (en) 2016-08-04 2022-03-01 Fanuc Corporation Stem cell manufacturing system, stem cell information management system, cell transport apparatus, and stem cell frozen storage apparatus
CA3053891C (en) 2017-02-27 2023-05-23 I Peace, Inc. Somatic cell production system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000270837A (ja) 1999-03-25 2000-10-03 Sanyo Electric Co Ltd インキュベータ
JP2005333912A (ja) 2004-05-28 2005-12-08 Yamaha Corp 小型培養観察装置
JP2012506257A (ja) 2008-10-22 2012-03-15 バイオベスト インターナショナル インコーポレイテッド 細胞および細胞由来生成物の産生のための、灌流バイオリアクター、細胞培養システム、および方法
WO2016093321A1 (ja) 2014-12-11 2016-06-16 株式会社アイカムス・ラボ 細胞培養方法及び細胞培養装置
WO2017038887A1 (ja) 2015-08-31 2017-03-09 アイ・ピース株式会社 多能性幹細胞製造システム

Also Published As

Publication number Publication date
EP4023746A1 (en) 2022-07-06
JPWO2021038997A1 (https=) 2021-03-04
EP4023746A4 (en) 2023-11-01
WO2021038997A1 (ja) 2021-03-04
CN114341337A (zh) 2022-04-12
US20220356436A1 (en) 2022-11-10

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