JP7278210B2 - ジストニアを治療するためのプリドピジンの使用 - Google Patents

ジストニアを治療するためのプリドピジンの使用 Download PDF

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JP7278210B2
JP7278210B2 JP2019531546A JP2019531546A JP7278210B2 JP 7278210 B2 JP7278210 B2 JP 7278210B2 JP 2019531546 A JP2019531546 A JP 2019531546A JP 2019531546 A JP2019531546 A JP 2019531546A JP 7278210 B2 JP7278210 B2 JP 7278210B2
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dystonia
pridopidine
patients
baseline
use according
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JP2019524897A5 (enExample
JP2019524897A (ja
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ヘイデン、マイケル
パパペトロパウロス、スピリドン
サヴォラ、ユハマッティ
エヤル、エリ
ボロウスキー、ベス
グラチェフ、イゴール・ディー
ゴードン、マーク・フォレスト
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プリレニア ニューロセラピューティクス リミテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/451Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2019531546A 2016-08-24 2017-08-24 ジストニアを治療するためのプリドピジンの使用 Active JP7278210B2 (ja)

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JP2021078788A JP7278327B2 (ja) 2016-08-24 2021-05-06 ジストニアを治療するためのプリドピジンの使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662379175P 2016-08-24 2016-08-24
US62/379,175 2016-08-24
US201662395319P 2016-09-15 2016-09-15
US62/395,319 2016-09-15
PCT/US2017/048458 WO2018039475A1 (en) 2016-08-24 2017-08-24 Use of pridopidine for treating dystonias

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JP2021078788A Division JP7278327B2 (ja) 2016-08-24 2021-05-06 ジストニアを治療するためのプリドピジンの使用

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JP2019524897A JP2019524897A (ja) 2019-09-05
JP2019524897A5 JP2019524897A5 (enExample) 2019-10-17
JP7278210B2 true JP7278210B2 (ja) 2023-05-19

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JP2021078788A Active JP7278327B2 (ja) 2016-08-24 2021-05-06 ジストニアを治療するためのプリドピジンの使用

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US (2) US11826361B2 (enExample)
EP (1) EP3503890B1 (enExample)
JP (2) JP7278210B2 (enExample)
CN (1) CN110012661A (enExample)
AU (1) AU2017315781B2 (enExample)
BR (1) BR112019003731A2 (enExample)
CA (1) CA3035099C (enExample)
DK (1) DK3503890T3 (enExample)
ES (1) ES3009437T3 (enExample)
MX (1) MX2019002190A (enExample)
PL (1) PL3503890T3 (enExample)
WO (1) WO2018039475A1 (enExample)

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WO2014205229A1 (en) 2013-06-21 2014-12-24 IVAX International GmbH Use of high dose pridopidine for treating huntington's disease
US11090297B2 (en) 2013-06-21 2021-08-17 Prilenia Neurotherapeutics Ltd. Pridopidine for treating huntington's disease
US11471449B2 (en) 2015-02-25 2022-10-18 Prilenia Neurotherapeutics Ltd. Use of pridopidine to improve cognitive function and for treating Alzheimer's disease
EP3590512A1 (en) 2015-02-25 2020-01-08 Prilenia Neurotherapeutics Ltd. Use of pridopidine to treat epilepsy
JP6912574B2 (ja) 2016-08-24 2021-08-04 プリレニア ニューロセラピューティクス リミテッド 機能低下を治療するためのプリドピジンの使用
BR112019003731A2 (pt) 2016-08-24 2019-07-16 Prilenia Therapeutics Dev Ltd aplicação de pridopidina para tratamento de distonias
US12102627B2 (en) 2016-09-16 2024-10-01 Prilenia Neurotherapeutics Ltd. Use of pridopidine for treating rett syndrome
US12036213B2 (en) 2017-09-08 2024-07-16 Prilenia Neurotherapeutics Ltd. Pridopidine for treating drug induced dyskinesias
MX383462B (es) 2017-09-08 2025-03-14 Prilenia Neurotherapeutics Ltd Pridopidina para el tratamiento de las discinesias inducidas por fármacos
US12357624B2 (en) 2019-02-04 2025-07-15 Prilenia Neurotherapeutics Ltd. Low dose pridopidine for Parkinson's Disease and other diseases associated with parkinsonism
BR112022022427A2 (pt) * 2020-05-04 2022-12-13 Prilenia Neurotherapeutics Ltd Tratamento de infecção, doença ou distúrbio viral com o uso de um agonista de s1r seletivo
AU2023420087A1 (en) * 2022-12-27 2025-07-10 Prilenia Neurotherapeutics Ltd. Pridopidine for treating juvenile huntington's disease
WO2024258929A1 (en) * 2023-06-12 2024-12-19 Unravel Biosciences, Inc. Methods for treating diseases associated with taf1 loss of function
US20250281500A1 (en) * 2024-03-06 2025-09-11 Ovid Therapeutics Inc. Fused amino pyrimidine compounds and pridopidine for treatment of huntington’s disease

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AU2005293754B2 (en) 2004-10-13 2011-07-21 Teva Pharmaceuticals International Gmbh Process for the synthesis of 4-(3-methanesulfonylphenyl)-1-N-propyl-piperidine
SE529246C2 (sv) * 2005-10-13 2007-06-12 Neurosearch Sweden Ab Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission
BRPI0810161A2 (pt) 2007-04-12 2014-12-30 Nsab Af Neurosearch Sweden Ab Composto, preparação farmacêutica, composição farmacêutica, e, uso de um composto
US8562488B2 (en) * 2009-10-05 2013-10-22 The Cleveland Clinic Foundation Systems and methods for improving motor function with assisted exercise
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EA201390332A1 (ru) 2010-09-03 2013-08-30 Ивакс Интернэшнл Гмбх Дейтерированные аналоги придопидина, применимые в качестве допаминергических стабилизаторов
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BR112019003731A2 (pt) 2016-08-24 2019-07-16 Prilenia Therapeutics Dev Ltd aplicação de pridopidina para tratamento de distonias
JP6912574B2 (ja) 2016-08-24 2021-08-04 プリレニア ニューロセラピューティクス リミテッド 機能低下を治療するためのプリドピジンの使用
JP2019529411A (ja) 2016-09-15 2019-10-17 プリレニア ニューロセラピューティクス リミテッド 不安症およびうつ病の治療のためのプリドピジンの使用
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Publication number Publication date
AU2017315781B2 (en) 2021-01-28
MX2019002190A (es) 2019-09-11
DK3503890T3 (da) 2025-01-27
JP2021119189A (ja) 2021-08-12
WO2018039475A1 (en) 2018-03-01
CA3035099A1 (en) 2018-03-01
BR112019003731A2 (pt) 2019-07-16
CN110012661A (zh) 2019-07-12
JP7278327B2 (ja) 2023-05-19
AU2017315781A1 (en) 2019-04-11
US20190192496A1 (en) 2019-06-27
PL3503890T3 (pl) 2025-03-24
CA3035099C (en) 2023-01-17
EP3503890A1 (en) 2019-07-03
EP3503890A4 (en) 2020-05-06
US20240075021A1 (en) 2024-03-07
WO2018039475A8 (en) 2018-10-04
US11826361B2 (en) 2023-11-28
JP2019524897A (ja) 2019-09-05
ES3009437T3 (en) 2025-03-26
EP3503890B1 (en) 2024-12-18

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