JP7255899B2 - 組織または流体から分子を選択的に除去するためのデバイス - Google Patents
組織または流体から分子を選択的に除去するためのデバイス Download PDFInfo
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- JP7255899B2 JP7255899B2 JP2020541421A JP2020541421A JP7255899B2 JP 7255899 B2 JP7255899 B2 JP 7255899B2 JP 2020541421 A JP2020541421 A JP 2020541421A JP 2020541421 A JP2020541421 A JP 2020541421A JP 7255899 B2 JP7255899 B2 JP 7255899B2
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- catheter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0283—Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
- A61M1/301—Details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
- A61M1/3659—Cannulae pertaining to extracorporeal circulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3687—Chemical treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3496—Plasmapheresis; Leucopheresis; Lymphopheresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
- A61M25/0026—Multi-lumen catheters with stationary elements
- A61M2025/0039—Multi-lumen catheters with stationary elements characterized by lumina being arranged coaxially
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0693—Brain, cerebrum
Description
DALI(登録商標)は、従来の治療が効かない高コレステロール血症の患者体内のリポタンパク質およびLDLコレステロールの直接吸着を可能にするデバイスである。
2 体表面
3 流体
4 標的分子
5 自然抗体
6 特異抗体またはアプタマー
7 主チャンバー
8 ナノ膜
8’ ナノ膜
9 第2のカテーテル
10 第3のカテーテル
11 二次チャンバー
12 微孔質膜
Claims (2)
- 組織または流体から分子を選択的に除去するためのデバイスであって、組織または流体中に自然抗体(5)とともに一連の標的分子(4)が存在し、前記デバイスは主カテーテル(1)で構成され、前記主カテーテルは、処置される前記流体(3)または組織に前記主カテーテルが到達するまで、対象となる体表面(2)に挿通することができ、主カテーテル(1)は前記標的分子(4)に対して特異抗体またはアプタマー(6)を挿入するためのものであり、前記主カテーテルは、前記標的分子(4)より大きいが、前記抗体、前記自然抗体(5)および前記特異抗体またはアプタマー(6)の両方より小さい細孔サイズを有するナノ膜(8)が位置決めされる主チャンバー(7)内で終端し、前記主チャンバー(7)がナノ膜(8’)を通して第2のカテーテル(9)と連通するという特別な特徴を有しており、前記ナノ膜(8’)は、前記標的分子(4)より大きいが、前記抗体より小さい細孔サイズを有し、前記第2のカテーテル(9)は特異抗体で処置された流体を除去し、濾過し、その結果標的分子(4)の濃度をより低くするための手段を備えることを特徴とする、組織または流体から分子を選択的に除去するためのデバイス。
- 前記デバイスは、第3の独立したカテーテル(10)を有し、前記第3の独立したカテーテル(10)は、二次チャンバー(11)内で終端し、前記主チャンバー(7)から独立しており、サイズに関係なく、前記組織または流体中のすべての前記分子によるアクセス、および前記流体への物質の投与を許容する微孔質膜(12)から形成される壁を有することを特徴とする、請求項1に記載の組織または流体から分子を選択的に除去するためのデバイス。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ESP201830130 | 2018-02-14 | ||
ES201830130A ES2722802B2 (es) | 2018-02-14 | 2018-02-14 | Dispositivo para la eliminacion selectiva de moleculas de tejidos o fluidos |
PCT/ES2019/070038 WO2019158791A1 (es) | 2018-02-14 | 2019-01-28 | Dispositivo para la eliminación selectiva de moléculas de tejidos o fluidos |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2021513383A JP2021513383A (ja) | 2021-05-27 |
JP7255899B2 true JP7255899B2 (ja) | 2023-04-11 |
Family
ID=67550830
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2020541421A Active JP7255899B2 (ja) | 2018-02-14 | 2019-01-28 | 組織または流体から分子を選択的に除去するためのデバイス |
Country Status (10)
Country | Link |
---|---|
US (1) | US11684746B2 (ja) |
EP (1) | EP3753598B1 (ja) |
JP (1) | JP7255899B2 (ja) |
CN (1) | CN111655320B (ja) |
AU (1) | AU2019221715B2 (ja) |
CA (1) | CA3088073A1 (ja) |
ES (2) | ES2722802B2 (ja) |
GB (1) | GB2583667B (ja) |
PL (1) | PL3753598T3 (ja) |
WO (1) | WO2019158791A1 (ja) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2010505556A (ja) | 2006-10-09 | 2010-02-25 | ニューロフルーディクス, インコーポレイテッド | 脳脊髄液精製システム |
US20100216226A1 (en) | 2009-02-25 | 2010-08-26 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Device, system, and method for controllably reducing inflammatory mediators in a subject |
JP2010227313A (ja) | 2009-03-27 | 2010-10-14 | Seiko Epson Corp | がん細胞除去システムおよびがん細胞除去装置 |
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JPH09509588A (ja) * | 1993-12-30 | 1997-09-30 | ボストン・サイエンティフィック・コーポレーション | 身体標本の採取 |
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FR2881339B1 (fr) * | 2005-02-02 | 2009-07-10 | Commissariat Energie Atomique | Dispositif de prelevement moleculaire par contact |
US9012238B2 (en) * | 2006-01-31 | 2015-04-21 | Biomed Solutions, Llc | Devices for selective recruitment, isolation, activation, and/or elimination of various cell populations |
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CN106166311B (zh) * | 2016-08-30 | 2018-07-13 | 张小曦 | 一种血浆净化系统及其应用 |
CN107260226B (zh) * | 2017-05-18 | 2020-07-10 | 华东医院 | 一种循环肿瘤细胞的体内富集装置 |
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2018
- 2018-02-14 ES ES201830130A patent/ES2722802B2/es active Active
-
2019
- 2019-01-28 ES ES19754457T patent/ES2935909T3/es active Active
- 2019-01-28 PL PL19754457.0T patent/PL3753598T3/pl unknown
- 2019-01-28 EP EP19754457.0A patent/EP3753598B1/en active Active
- 2019-01-28 JP JP2020541421A patent/JP7255899B2/ja active Active
- 2019-01-28 WO PCT/ES2019/070038 patent/WO2019158791A1/es unknown
- 2019-01-28 AU AU2019221715A patent/AU2019221715B2/en active Active
- 2019-01-28 CN CN201980010115.XA patent/CN111655320B/zh active Active
- 2019-01-28 CA CA3088073A patent/CA3088073A1/en active Pending
- 2019-01-28 GB GB2010986.4A patent/GB2583667B/en active Active
- 2019-01-28 US US16/964,151 patent/US11684746B2/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2010505556A (ja) | 2006-10-09 | 2010-02-25 | ニューロフルーディクス, インコーポレイテッド | 脳脊髄液精製システム |
US20100216226A1 (en) | 2009-02-25 | 2010-08-26 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Device, system, and method for controllably reducing inflammatory mediators in a subject |
JP2010227313A (ja) | 2009-03-27 | 2010-10-14 | Seiko Epson Corp | がん細胞除去システムおよびがん細胞除去装置 |
Also Published As
Publication number | Publication date |
---|---|
GB202010986D0 (en) | 2020-09-02 |
US20210030941A1 (en) | 2021-02-04 |
GB2583667B (en) | 2022-02-23 |
CA3088073A1 (en) | 2019-08-22 |
GB2583667A (en) | 2020-11-04 |
PL3753598T3 (pl) | 2023-03-20 |
US11684746B2 (en) | 2023-06-27 |
EP3753598B1 (en) | 2022-11-23 |
JP2021513383A (ja) | 2021-05-27 |
AU2019221715A1 (en) | 2020-07-30 |
ES2722802A1 (es) | 2019-08-16 |
ES2935909T8 (es) | 2023-06-29 |
GB2583667A8 (en) | 2020-11-18 |
CN111655320B (zh) | 2022-04-26 |
WO2019158791A1 (es) | 2019-08-22 |
ES2935909T3 (es) | 2023-03-13 |
EP3753598A4 (en) | 2021-11-10 |
CN111655320A (zh) | 2020-09-11 |
EP3753598A1 (en) | 2020-12-23 |
ES2722802B2 (es) | 2019-12-18 |
AU2019221715B2 (en) | 2024-01-18 |
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