JP7249955B2 - ヒトIL-27のαサブユニットの分泌可能なムテイン - Google Patents
ヒトIL-27のαサブユニットの分泌可能なムテイン Download PDFInfo
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
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- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2319/50—Fusion polypeptide containing protease site
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| EP17169358.3 | 2017-05-04 | ||
| PCT/EP2018/061561 WO2018202876A1 (en) | 2017-05-04 | 2018-05-04 | Secretion-competent muteins of the human il-27 alpha-subunit |
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| JP2020518249A JP2020518249A (ja) | 2020-06-25 |
| JP2020518249A5 JP2020518249A5 (enExample) | 2021-06-17 |
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| EP3955955B1 (en) | 2019-04-19 | 2025-02-26 | Synerkine Pharma B.V. | A fusion protein comprising il13 |
| JP2023501515A (ja) * | 2019-11-12 | 2023-01-18 | テクニッシェ ウニヴェルズィテート ミュンヘン | ヒトIL-27αサブユニットの均質ムテイン |
| WO2024213695A1 (en) * | 2023-04-14 | 2024-10-17 | Technische Universitaet Muenchen | Method for producing the subunits of human interleukin 35 from interleukin 12 and interleukin 27 |
| CN116832146B (zh) * | 2023-06-30 | 2024-02-13 | 广东暨安特博生物科技有限公司 | Il-27蛋白在制备治疗阿尔茨海默症的产品的应用 |
| WO2025140436A1 (zh) * | 2023-12-27 | 2025-07-03 | 上海药明生物技术有限公司 | 重组il-27蛋白及其制备方法 |
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| JP4839434B2 (ja) * | 2005-03-14 | 2011-12-21 | 千葉県 | p28分子またはその遺伝子を含む医薬製剤 |
| HK1206764A1 (en) * | 2012-03-26 | 2016-01-15 | Axcella Health Inc. | Nutritive proteins and methods |
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- 2018-05-04 CA CA3060219A patent/CA3060219A1/en active Pending
Non-Patent Citations (3)
| Title |
|---|
| Database NCBI Reference Sequence [online], NP_663611, 2015-02-15uploaded, [retrieved on 2022-04-20], < https://www.ncbi.nlm.nih.gov/protein/21704110?sat=46&satkey=70707665>, interleukin-27 subunit alpha precursor[Mus musculus] |
| Database NCBI Reference Sequence [online], NP_663634, 2016-10-15uploaded, [retrieved on 2022-04-20], <https://www.ncbi.nlm.nih.gov/protein/28416913?sat=46&satkey=69182784>,Definition: interleukin-27 subunit alpha precursor [Homo sapiens] |
| Database NCBI Reference Sequence [online], XP_003281965, 2015-05-13uploaded, [retrieved on 2022-04-19], < https://www.ncbi.nlm.nih.gov/protein/332265926?sat=47&satkey=95882820>, Definition: PREDICTED: interleukin-27subunit alpha [Nomascus leucogenys] |
Also Published As
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| CN110709413A (zh) | 2020-01-17 |
| US20200062817A1 (en) | 2020-02-27 |
| WO2018202876A1 (en) | 2018-11-08 |
| AU2018262811B2 (en) | 2021-10-21 |
| US11358998B2 (en) | 2022-06-14 |
| CN110709413B (zh) | 2023-11-28 |
| EP3619228A1 (en) | 2020-03-11 |
| JP2020518249A (ja) | 2020-06-25 |
| AU2018262811A1 (en) | 2019-12-19 |
| CA3060219A1 (en) | 2018-11-08 |
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