JP7229768B2 - カッパ骨髄腫抗原キメラ抗原受容体およびその使用 - Google Patents
カッパ骨髄腫抗原キメラ抗原受容体およびその使用 Download PDFInfo
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| JP2022209702A Division JP2023024793A (ja) | 2015-04-23 | 2022-12-27 | カッパ骨髄腫抗原キメラ抗原受容体およびその使用 |
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| EP4368641A3 (en) | 2015-04-23 | 2024-08-14 | HaemaLogiX Ltd. | Kappa myeloma antigen chimeric antigen receptors and uses thereof |
| CN107529550A (zh) * | 2017-08-28 | 2018-01-02 | 马晓冬 | 一种基于PiggyBac载体的CD‑19‑CAR‑T系统构建方法 |
| WO2019047932A1 (zh) * | 2017-09-08 | 2019-03-14 | 科济生物医药（上海）有限公司 | 基因工程化的t细胞及应用 |
| WO2019108932A1 (en) * | 2017-11-30 | 2019-06-06 | Haemalogix Pty. Ltd. | Methods for expanding kappa myeloma antigen chimeric antigen receptors expressing cells |
| WO2019201995A1 (en) * | 2018-04-20 | 2019-10-24 | Medizinische Hochschule Hannover | Chimeric antigen receptor and car-t cells that bind a herpes virus antigen |
| JPWO2020004337A1 (ja) * | 2018-06-27 | 2021-08-02 | 国立大学法人東海国立大学機構 | Ｃｄ３７特異的キメラ抗原レセプター |
| US20220177573A1 (en) | 2018-07-09 | 2022-06-09 | Oslo Universitetssykehus Hf | Two chimeric antigen receptors specifically binding cd19 and igkappa |
| CN110832071A (zh) * | 2018-09-14 | 2020-02-21 | 上海原能细胞医学技术有限公司 | 表面包含免疫调节剂的细胞及其用途 |
| EP3890780A4 (en) * | 2018-12-03 | 2022-08-17 | HaemaLogiX Pty Ltd. | METHOD OF TREATMENT |
| US20220175833A1 (en) * | 2019-03-07 | 2022-06-09 | Children's Medical Center Corporation | Targeted delivery of immune-modulating vhh and vhh-fusion protein |
| KR20220012328A (ko) * | 2019-05-24 | 2022-02-03 | 포티 세븐, 인코포레이티드 | c-kit 및 CD47에 대한 면역요법제의 병용 투여를 위한 요법 |
| CN110305906B (zh) * | 2019-07-18 | 2021-11-12 | 山东大学第二医院 | 一种靶向pdl1的car嵌合受体的慢病毒载体及pdl1-car-t细胞 |
| KR20220137882A (ko) * | 2019-12-05 | 2022-10-12 | 바이셀릭스, 인크. | 보편적 세포 요법을 위한 면역 회피 기작의 조절제 |
| CA3176109A1 (en) * | 2020-03-27 | 2021-09-30 | Haemalogix Pty Ltd | Composition and method |
| IL297851A (en) | 2020-05-04 | 2023-01-01 | Saliogen Therapeutics Inc | Transposition-based treatments |
| WO2021232200A1 (en) * | 2020-05-18 | 2021-11-25 | Guangdong Tcrcure Biopharma Technology Co., Ltd. | Il-12 armored immune cell therapy and uses thereof |
| EP4263600A1 (en) | 2020-12-18 | 2023-10-25 | Century Therapeutics, Inc. | Chimeric antigen receptor systems with adaptable receptor specificity |
| WO2022268196A1 (zh) * | 2021-06-25 | 2022-12-29 | 天辰生物医药(苏州)有限公司 | 靶向gpc3的抗原结合蛋白 |
| WO2023010118A1 (en) * | 2021-07-29 | 2023-02-02 | Vor Biopharma Inc. | Nfat-responsive reporter systems for assessing chimeric antigen receptor activation and methods of making and using the same |
| KR102789265B1 (ko) * | 2022-04-14 | 2025-04-02 | 주식회사 셀랩메드 | 키메릭 항원 수용체 및 hgf 결합 억제 물질의 조합 요법 |
| WO2024196796A1 (en) * | 2023-03-17 | 2024-09-26 | Cartesian Therapeutics, Inc. | Intracellular signaling and costimulatory domains adapted for prolonged expression of chimeric antigen receptors |
| WO2025136986A2 (en) | 2023-12-18 | 2025-06-26 | Genzyme Corporation | Il-12 loss of potency muteins |
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| CA2507080C (en) * | 2002-11-27 | 2015-01-06 | Biogen Idec Ma Inc. | Humanized antibodies against monocyte chemotactic proteins |
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| US9212229B2 (en) | 2010-09-08 | 2015-12-15 | Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus | Chimeric antigen receptors with an optimized hinge region |
| US20140322216A1 (en) * | 2011-11-08 | 2014-10-30 | The Trustees Of The University Of Pennsylvania | Glypican-3-specific antibody and uses thereof |
| WO2014100689A1 (en) * | 2012-12-21 | 2014-06-26 | Aveo Pharmaceuticals, Inc. | Anti-gdf15 antibodies |
| WO2014190273A1 (en) | 2013-05-24 | 2014-11-27 | Board Of Regents, The University Of Texas System | Chimeric antigen receptor-targeting monoclonal antibodies |
| CN104177499B (zh) * | 2013-05-27 | 2019-01-08 | 上海雅科生物科技有限公司 | 一种嵌合抗原受体、编码基因、表达载体及其应用 |
| US10208125B2 (en) * | 2013-07-15 | 2019-02-19 | University of Pittsburgh—of the Commonwealth System of Higher Education | Anti-mucin 1 binding agents and uses thereof |
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