JP7222711B2 - タンパク質及びｋｌｅｂｓｉｅｌｌａタンパク質を含有する免疫化組成物ならびにその使用方法 - Google Patents

タンパク質及びｋｌｅｂｓｉｅｌｌａタンパク質を含有する免疫化組成物ならびにその使用方法 Download PDF

Info

Publication number
JP7222711B2
JP7222711B2 JP2018521193A JP2018521193A JP7222711B2 JP 7222711 B2 JP7222711 B2 JP 7222711B2 JP 2018521193 A JP2018521193 A JP 2018521193A JP 2018521193 A JP2018521193 A JP 2018521193A JP 7222711 B2 JP7222711 B2 JP 7222711B2
Authority
JP
Japan
Prior art keywords
seq
identity
amino acid
composition
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2018521193A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018527405A (ja
JP2018527405A5 (enExample
Inventor
ダグラス ティー． ブルクハルト，
ダリル エメリー，
ダレン ストラウブ，
Original Assignee
エピトピックス， エルエルシー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by エピトピックス， エルエルシー filed Critical エピトピックス， エルエルシー
Publication of JP2018527405A publication Critical patent/JP2018527405A/ja
Publication of JP2018527405A5 publication Critical patent/JP2018527405A5/ja
Application granted granted Critical
Publication of JP7222711B2 publication Critical patent/JP7222711B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0266—Klebsiella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/116—Polyvalent bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/26—Klebsiella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2018521193A 2015-07-10 2016-07-08 タンパク質及びｋｌｅｂｓｉｅｌｌａタンパク質を含有する免疫化組成物ならびにその使用方法 Active JP7222711B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562190947P 2015-07-10 2015-07-10
US62/190,947 2015-07-10
PCT/US2016/041614 WO2017011340A2 (en) 2015-07-10 2016-07-08 Proteins and immunizing compositions containing klebsiella proteins and methods of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020206603A Division JP2021063084A (ja) 2015-07-10 2020-12-14 タンパク質及びｋｌｅｂｓｉｅｌｌａタンパク質を含有する免疫化組成物ならびにその使用方法

Publications (3)

Publication Number Publication Date
JP2018527405A JP2018527405A (ja) 2018-09-20
JP2018527405A5 JP2018527405A5 (enExample) 2019-08-15
JP7222711B2 true JP7222711B2 (ja) 2023-02-15

Family

ID=56555778

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018521193A Active JP7222711B2 (ja) 2015-07-10 2016-07-08 タンパク質及びｋｌｅｂｓｉｅｌｌａタンパク質を含有する免疫化組成物ならびにその使用方法
JP2020206603A Withdrawn JP2021063084A (ja) 2015-07-10 2020-12-14 タンパク質及びｋｌｅｂｓｉｅｌｌａタンパク質を含有する免疫化組成物ならびにその使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2020206603A Withdrawn JP2021063084A (ja) 2015-07-10 2020-12-14 タンパク質及びｋｌｅｂｓｉｅｌｌａタンパク質を含有する免疫化組成物ならびにその使用方法

Country Status (7)

Country Link
US (3) US11000582B2 (enExample)
EP (1) EP3319628A2 (enExample)
JP (2) JP7222711B2 (enExample)
CN (1) CN107921114A (enExample)
CA (1) CA2991907A1 (enExample)
MX (1) MX2018000395A (enExample)
WO (1) WO2017011340A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002053180A2 (en) * 2001-01-03 2002-07-11 Willmar Poultry Company, Inc. Immunizing compositions and methods of use
CA2991907A1 (en) * 2015-07-10 2017-01-19 Douglas T. Burkhardt Proteins and immunizing compositions containing klebsiella proteins and methods of use
US10166280B2 (en) 2016-06-08 2019-01-01 Epitopix, Llc Polypeptides and immunizing compositions containing Bacillus polypeptides and methods of use
ES2945137T3 (es) 2017-02-10 2023-06-28 Epitopix Llc Proteínas y composiciones inmunitarias que contienen proteínas de Pasteurella y métodos de uso
CA3138237A1 (en) * 2019-04-26 2020-10-29 Cornell University Klebsiella vaccine and methods of use
CN111647057B (zh) * 2020-05-07 2022-09-13 西南医科大学附属中医医院 一种伤寒沙门菌疫苗重组蛋白及其编码基因和它们的应用
EP4422677A1 (en) * 2021-10-29 2024-09-04 Vaxxinova US, Inc. Methods and compositions for preventing infection
CN115975890A (zh) * 2023-02-02 2023-04-18 深圳元健生命科技有限公司 一种产气克雷伯氏菌及其应用
CN115798574B (zh) * 2023-02-06 2023-06-02 中国医学科学院北京协和医院 一种预测克雷伯氏菌属对美罗培南敏感性的系统及方法
CN119679930B (zh) * 2025-02-24 2025-07-25 吉林大学第一医院 一种肺炎克雷伯菌表面膜蛋白的应用和疫苗
CN120330106B (zh) * 2025-06-05 2025-08-26 云南省农业科学院茶叶研究所 一种产酸克雷伯氏菌株及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2644346B1 (fr) * 1989-03-20 1994-05-13 Rhone Merieux Vaccins contre les bacteries septicemiques, preparations d'antigenes de bacteries septicemiques, nouvelles bacteries et vecteurs pour la preparation de ces antigenes ou vaccins
CA2182976C (en) 1994-02-09 2011-07-12 Daryll A. Emery Active immunization using a siderophore receptor protein
US5538733A (en) 1994-07-07 1996-07-23 Willmar Poultry Company, Inc. Method of priming an immune response in a one-day old animal
US6610836B1 (en) 1999-01-29 2003-08-26 Genome Therapeutics Corporation Nucleic acid amino acid sequences relating to Klebsiella pneumoniae for diagnostics and therapeutics
US6682754B2 (en) 1999-11-24 2004-01-27 Willmar Poultry Company, Inc. Ovo delivery of an immunogen containing implant
WO2002053180A2 (en) 2001-01-03 2002-07-11 Willmar Poultry Company, Inc. Immunizing compositions and methods of use
BRPI0414267A (pt) 2003-09-19 2006-11-21 Epitopix Llc polipeptìdeos de campilobacter e métodos de uso
BRPI0607323B8 (pt) 2005-02-14 2021-05-25 Epitopix Llc composições, usos de polipeptídeos e de anticorpos, bem como kits para a detecção de anticorpo que se liga especificamente a um polipeptídeo
EP2152731A2 (en) * 2007-05-02 2010-02-17 Intercell AG Klebsiella antigens
BRPI1011856A2 (pt) * 2009-03-23 2020-11-03 Epitopix, Llc polipeptídeos e composições de imunização contendo polipeptídeos gram-positivos e métodos de uso
US9073990B2 (en) * 2010-04-05 2015-07-07 Bar-Llan University Protease-activatable pore-forming polypeptides
CA2991907A1 (en) * 2015-07-10 2017-01-19 Douglas T. Burkhardt Proteins and immunizing compositions containing klebsiella proteins and methods of use

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Ｉｎｆｅｃｔ． Ｉｍｍｕｎ． （１９８５） ｖｏｌ．４８， ｎｏ．１， ｐ．３５－３９
Ｊ． Ｂａｃｔｅｒｉｏｌ． （１９８６） ｖｏｌ．１６５， ｎｏ．２， ｐ．３５３－３５６

Also Published As

Publication number Publication date
WO2017011340A2 (en) 2017-01-19
CN107921114A (zh) 2018-04-17
US20210330776A1 (en) 2021-10-28
US20240216494A1 (en) 2024-07-04
EP3319628A2 (en) 2018-05-16
US20190070281A1 (en) 2019-03-07
WO2017011340A3 (en) 2017-04-13
CA2991907A1 (en) 2017-01-19
US11872273B2 (en) 2024-01-16
US11000582B2 (en) 2021-05-11
JP2021063084A (ja) 2021-04-22
JP2018527405A (ja) 2018-09-20
MX2018000395A (es) 2018-05-23

Similar Documents

Publication Publication Date Title
US20240216494A1 (en) Proteins and immunizing compositions containing klebsiella proteins and methods of use
JP6100826B2 (ja) 黄色ブドウ球菌由来のポリペプチド及び使用方法
US8329192B2 (en) Campylobacter polypeptides and methods of use
JP6092933B2 (ja) ポリペプチド及びグラム陽性ポリペプチドを含有する免疫化組成物並びにこれらの使用方法
US20250255950A1 (en) Proteins and immunizing compositions containing pasteurella proteins and methods of use
US12178866B2 (en) Polypeptides of fusobacterium and methods of use
BR122025008885A2 (pt) Composições, usos das mesmas, e kits
AU2010229498B2 (en) Polypeptides and immunizing compositions containing gram positive polypeptides and methods of use

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190705

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20190705

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20200615

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20200909

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20201214

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20210423

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210823

C60 Trial request (containing other claim documents, opposition documents)

Free format text: JAPANESE INTERMEDIATE CODE: C60

Effective date: 20210823

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20210831

C21 Notice of transfer of a case for reconsideration by examiners before appeal proceedings

Free format text: JAPANESE INTERMEDIATE CODE: C21

Effective date: 20210901

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20210924

C211 Notice of termination of reconsideration by examiners before appeal proceedings

Free format text: JAPANESE INTERMEDIATE CODE: C211

Effective date: 20210928

C22 Notice of designation (change) of administrative judge

Free format text: JAPANESE INTERMEDIATE CODE: C22

Effective date: 20220711

C13 Notice of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: C13

Effective date: 20220829

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20221129

C23 Notice of termination of proceedings

Free format text: JAPANESE INTERMEDIATE CODE: C23

Effective date: 20221219

C03 Trial/appeal decision taken

Free format text: JAPANESE INTERMEDIATE CODE: C03

Effective date: 20230118

C30A Notification sent

Free format text: JAPANESE INTERMEDIATE CODE: C3012

Effective date: 20230118

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20230203

R150 Certificate of patent or registration of utility model

Ref document number: 7222711

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150