JP7219220B2 - 改善された血清アルブミン結合剤 - Google Patents
改善された血清アルブミン結合剤 Download PDFInfo
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- JP7219220B2 JP7219220B2 JP2019538382A JP2019538382A JP7219220B2 JP 7219220 B2 JP7219220 B2 JP 7219220B2 JP 2019538382 A JP2019538382 A JP 2019538382A JP 2019538382 A JP2019538382 A JP 2019538382A JP 7219220 B2 JP7219220 B2 JP 7219220B2
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- serum albumin
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Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022196232A JP7628996B2 (ja) | 2017-01-17 | 2022-12-08 | 改善された血清アルブミン結合剤 |
| JP2024204085A JP2025026992A (ja) | 2017-01-17 | 2024-11-22 | 改善された血清アルブミン結合剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762446988P | 2017-01-17 | 2017-01-17 | |
| US62/446,988 | 2017-01-17 | ||
| PCT/EP2018/051083 WO2018134235A1 (en) | 2017-01-17 | 2018-01-17 | Improved serum albumin binders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022196232A Division JP7628996B2 (ja) | 2017-01-17 | 2022-12-08 | 改善された血清アルブミン結合剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020515518A JP2020515518A (ja) | 2020-05-28 |
| JP2020515518A5 JP2020515518A5 (enExample) | 2021-01-07 |
| JP7219220B2 true JP7219220B2 (ja) | 2023-02-07 |
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| JP2019538382A Active JP7219220B2 (ja) | 2017-01-17 | 2018-01-17 | 改善された血清アルブミン結合剤 |
| JP2022196232A Active JP7628996B2 (ja) | 2017-01-17 | 2022-12-08 | 改善された血清アルブミン結合剤 |
| JP2024204085A Pending JP2025026992A (ja) | 2017-01-17 | 2024-11-22 | 改善された血清アルブミン結合剤 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022196232A Active JP7628996B2 (ja) | 2017-01-17 | 2022-12-08 | 改善された血清アルブミン結合剤 |
| JP2024204085A Pending JP2025026992A (ja) | 2017-01-17 | 2024-11-22 | 改善された血清アルブミン結合剤 |
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| Country | Link |
|---|---|
| US (2) | US11414481B2 (enExample) |
| EP (3) | EP3571225B1 (enExample) |
| JP (3) | JP7219220B2 (enExample) |
| KR (2) | KR20240013861A (enExample) |
| CN (2) | CN110191896B (enExample) |
| AU (2) | AU2018209151B2 (enExample) |
| BR (1) | BR112019014599A2 (enExample) |
| CA (1) | CA3050575A1 (enExample) |
| DK (1) | DK3571225T3 (enExample) |
| ES (1) | ES2991459T3 (enExample) |
| FI (1) | FI3571225T3 (enExample) |
| HR (1) | HRP20241469T1 (enExample) |
| HU (1) | HUE068790T2 (enExample) |
| IL (2) | IL267894B2 (enExample) |
| LT (1) | LT3571225T (enExample) |
| MX (2) | MX2019008496A (enExample) |
| PT (1) | PT3571225T (enExample) |
| RS (1) | RS66117B1 (enExample) |
| SG (2) | SG10202108972RA (enExample) |
| SI (1) | SI3571225T1 (enExample) |
| WO (1) | WO2018134235A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023025232A (ja) * | 2017-01-17 | 2023-02-21 | アブリンクス エン．ヴェー． | 改善された血清アルブミン結合剤 |
Families Citing this family (39)
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| US11644471B2 (en) | 2010-09-30 | 2023-05-09 | Ablynx N.V. | Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains |
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