JP7198218B2 - 薬剤付与器具および薬剤層の形成方法 - Google Patents
薬剤付与器具および薬剤層の形成方法 Download PDFInfo
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Description
本発明の第1実施形態に係る薬剤付与器具10は、図1、2に示すように、血管等の生体管腔の狭窄部に挿入して押し広げるためのバルーン30(図3を参照)の表面に、薬剤の層を配置し、薬剤溶出型のバルーンとするためのデバイスである。なお、薬剤付与器具10により薬剤の層を配置する医療器具は、バルーン30に限定されず、例えば、ガイドワイヤ、ガイディングシース、ガイディングカテーテル、ステント等であってもよい。以下では、薬剤付与器具10によりバルーン30に薬剤の層を配置する場合を例示する。
本発明の第2実施形態に係る薬剤付与器具60は、図8、9に示すように、筒状である点で、第1実施形態と異なる。なお、第1実施形態と同様の機能を有する部位には、同一の符号を付し、説明を省略する。
本発明の第3実施形態に係る薬剤付与器具70は、図14に示すように、帯状の長尺なテープ状である点で、第1実施形態と異なる。なお、第1実施形態と同様の機能を有する部位には、同一の符号を付し、説明を省略する。薬剤付与器具70は、形状以外の構造(シート11、薬剤層12、接着層13)は、第1実施形態と同様である。
11 シート
12 薬剤層
13 接着層
14 貫通孔
30 バルーン(医療器具)
61 熱収縮チューブ(シート)
Claims (12)
- 生体内に挿入して使用される医療器具に張り付け可能な薬剤付与器具であって、
柔軟なシートと、
前記シートの一方面に設けられる薬剤層と、を有し、
前記薬剤層は、前記薬剤付与器具が前記医療器具に張り付けられる前に事前に前記シートの一方面に設けられ、
前記シートは、熱収縮チューブである薬剤付与器具。 - 前記シートの前記薬剤層が設けられる側と反対側の面に設けられる接着層をさらに有する請求項1に記載の薬剤付与器具。
- 前記接着層は、加熱により接着力を発揮する請求項2に記載の薬剤付与器具。
- 前記シートは、筒状であり、前記薬剤層は、前記シートの外周面に設けられる請求項1~3のいずれか1項に記載の薬剤付与器具。
- 前記医療器具は、拡張および収縮が可能なバルーンである請求項1~4のいずれか1項に記載の薬剤付与器具。
- 前記薬剤層の薬剤は、水不溶性薬剤、水溶性薬剤、親水性ポリマーからなる群から選択される少なくとも1つを含有する請求項1~5のいずれか1項に記載の薬剤付与器具。
- 生体内に挿入して使用される医療器具の表面に薬剤を配置するための薬剤層の形成方法であって、
柔軟なシートの一方面に薬剤層が設けられた薬剤付与器具の前記薬剤層が設けられる側の反対面を、前記医療器具の表面に張り付けるステップを有し、
前記薬剤層は、前記薬剤付与器具が前記医療器具に張り付けられる前に事前に前記シートの一方面に設けられ、
前記シートは、熱収縮チューブである薬剤層の形成方法。 - 前記張り付けるステップにおいて、前記シートの前記薬剤層が設けられる側の反対面に設けられる接着層を前記医療器具の表面に接着させる請求項7に記載の薬剤層の形成方法。
- 前記張り付けるステップにおいて、前記接着層を加熱して前記接着層に接着力を発揮させる請求項8に記載の薬剤層の形成方法。
- 前記シートは、筒状であり、前記薬剤層は、前記シートの外周面に設けられる請求項7~9のいずれか1項に記載の薬剤層の形成方法。
- 前記張り付けるステップにおいて、生体内から抜去した医療器具に前記薬剤付与器具を張り付ける請求項7~10のいずれか1項に記載の薬剤層の形成方法。
- 前記医療器具は、拡張および収縮が可能なバルーン、ガイドワイヤ、ガイディングシース、ガイディングカテーテルまたはステントである請求項7~11のいずれか1項に記載の薬剤層の形成方法。
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CN114949551A (zh) * | 2021-06-01 | 2022-08-30 | 深圳市本尚医疗科技有限公司 | 多孔球囊导管系统及其使用方法 |
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