JP7197915B2 - エンザスタウリンの活性を予測するための方法および組成物 - Google Patents

エンザスタウリンの活性を予測するための方法および組成物 Download PDF

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JP7197915B2
JP7197915B2 JP2019512609A JP2019512609A JP7197915B2 JP 7197915 B2 JP7197915 B2 JP 7197915B2 JP 2019512609 A JP2019512609 A JP 2019512609A JP 2019512609 A JP2019512609 A JP 2019512609A JP 7197915 B2 JP7197915 B2 JP 7197915B2
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ウェン ルオ,
ホン スン,
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デノボ バイオファーマ エルエルシー
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    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00Oligonucleotides characterized by their use
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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JP2019512609A 2016-09-01 2017-08-31 エンザスタウリンの活性を予測するための方法および組成物 Active JP7197915B2 (ja)

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JP2022148064A JP2022173308A (ja) 2016-09-01 2022-09-16 エンザスタウリンの活性を予測するための方法および組成物

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US201662382734P 2016-09-01 2016-09-01
US62/382,734 2016-09-01
US201662414601P 2016-10-28 2016-10-28
US62/414,601 2016-10-28
PCT/US2017/049747 WO2018045240A1 (en) 2016-09-01 2017-08-31 Methods and composition for the prediction of the activity of enzastaurin

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JP2020142358A Division JP2020188816A (ja) 2016-09-01 2020-08-26 エンザスタウリンの活性を予測するための方法および組成物
JP2022148064A Division JP2022173308A (ja) 2016-09-01 2022-09-16 エンザスタウリンの活性を予測するための方法および組成物

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JP2019528705A JP2019528705A (ja) 2019-10-17
JP2019528705A5 JP2019528705A5 (enExample) 2020-10-08
JP7197915B2 true JP7197915B2 (ja) 2022-12-28

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JP2019512609A Active JP7197915B2 (ja) 2016-09-01 2017-08-31 エンザスタウリンの活性を予測するための方法および組成物
JP2020142358A Pending JP2020188816A (ja) 2016-09-01 2020-08-26 エンザスタウリンの活性を予測するための方法および組成物
JP2022148064A Withdrawn JP2022173308A (ja) 2016-09-01 2022-09-16 エンザスタウリンの活性を予測するための方法および組成物

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JP2022148064A Withdrawn JP2022173308A (ja) 2016-09-01 2022-09-16 エンザスタウリンの活性を予測するための方法および組成物

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US (2) US11421280B2 (enExample)
EP (1) EP3507384B1 (enExample)
JP (3) JP7197915B2 (enExample)
KR (1) KR20190046935A (enExample)
CN (1) CN109952383B (enExample)
AU (1) AU2017318669B2 (enExample)
BR (1) BR112019003951A2 (enExample)
CA (1) CA3035386A1 (enExample)
JO (1) JOP20190025A1 (enExample)
MX (1) MX2019002377A (enExample)
PH (1) PH12019500422A1 (enExample)
RU (1) RU2019109011A (enExample)
SG (2) SG11201901762WA (enExample)
TW (2) TW202313973A (enExample)
WO (1) WO2018045240A1 (enExample)

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JOP20190025A1 (ar) 2016-09-01 2019-02-19 Denovo Biopharma Llc طرق وتركيبة لتوقع نشاط إنزاستورين
CN110496223B (zh) * 2018-05-17 2021-09-10 复旦大学附属肿瘤医院 一种治疗非霍奇金氏淋巴瘤的药物组合物
US20220193062A1 (en) * 2018-09-12 2022-06-23 Denovo Biopharma Llc Combination of enzastaurin and inhibitors of btk and uses thereof
CN111549033B (zh) * 2020-06-11 2021-02-12 南京市江宁医院 慢病毒感染人表皮角质细胞株及其构建方法和应用
US11227690B1 (en) * 2020-09-14 2022-01-18 Opendna Ltd. Machine learning prediction of therapy response
TWI808838B (zh) * 2021-07-23 2023-07-11 高雄醫學大學 二代荷爾蒙藥物於治療攝護腺癌療效評估之臨床治療藥物預測暨推薦系統及方法
US20230131677A1 (en) * 2021-10-21 2023-04-27 Toyota Research Institute, Inc. Systems and methods for predicting the effect of an intervention via machine learning
CN118339312A (zh) * 2021-11-23 2024-07-12 索元生物医药(美国)有限公司 用于评估多核苷酸递送和癌疗法之功效的组合物和方法
US12474842B2 (en) * 2021-12-13 2025-11-18 Google Llc Optimizing data placement based on data temperature and lifetime prediction

Citations (1)

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JP2014506459A (ja) 2011-01-31 2014-03-17 デノボ バイオマーカーズ インコーポレイテッド 薬理ゲノミクスバイオマーカーを発見するための方法

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US20040072217A1 (en) 2002-06-17 2004-04-15 Affymetrix, Inc. Methods of analysis of linkage disequilibrium
CA2393720C (en) 2002-07-12 2010-09-14 Eli Lilly And Company Crystalline 2,5-dione-3-(1-methyl-1h-indol-3-yl)-4-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1h-indol-3-yl]-1h-pyrrole mono-hydrochloride
WO2007145992A2 (en) 2006-06-05 2007-12-21 Perlegen Sciences, Inc. Genetic basis of treatment response in depression patients
EP2718486A4 (en) * 2011-06-08 2014-12-31 Denovo Biopharma Hangzhou Ltd Co METHODS AND COMPOSITIONS FOR PREDICTING THE ACTIVITY OF A RETINOID RECEPTOR X MODULATOR
JOP20190025A1 (ar) 2016-09-01 2019-02-19 Denovo Biopharma Llc طرق وتركيبة لتوقع نشاط إنزاستورين

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JP2014506459A (ja) 2011-01-31 2014-03-17 デノボ バイオマーカーズ インコーポレイテッド 薬理ゲノミクスバイオマーカーを発見するための方法

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Denovo Biopharma acquires late-stage oncology drug from Lilly for development as a personalized medicine,DENOVO BIOMARKERS HOMEPAGE [ONLINE],2014年09月16日,http://www.denovobiopharma.com/Denovo_Lilly_News.html,[検索日令和3年5月26日]
MOLECULAR CANCER THERAPEUTICS,2010年,Vol.9, No.10,p.2814-2824
NEURO-ONCOLOGY,2011年,Vol.13, No.12,p.1331-1338

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PH12019500422A1 (en) 2019-05-27
RU2019109011A3 (enExample) 2021-01-22
AU2017318669A1 (en) 2019-03-07
MX2019002377A (es) 2019-09-05
CN109952383B (zh) 2024-01-05
CN109952383A (zh) 2019-06-28
BR112019003951A2 (pt) 2019-06-25
US11421280B2 (en) 2022-08-23
TW202313973A (zh) 2023-04-01
SG11201901762WA (en) 2019-03-28
US20230074781A1 (en) 2023-03-09
TWI771317B (zh) 2022-07-21
US20190233902A1 (en) 2019-08-01
TW201812125A (zh) 2018-04-01
JP2022173308A (ja) 2022-11-18
EP3507384B1 (en) 2023-08-30
JP2019528705A (ja) 2019-10-17
RU2019109011A (ru) 2020-10-05
SG10201912134TA (en) 2020-02-27
KR20190046935A (ko) 2019-05-07
AU2017318669B2 (en) 2023-04-20
CA3035386A1 (en) 2018-03-08
WO2018045240A1 (en) 2018-03-08
EP3507384A1 (en) 2019-07-10
JP2020188816A (ja) 2020-11-26
JOP20190025A1 (ar) 2019-02-19

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