JP7197369B2 - コンパクトなガス分析装置及び方法 - Google Patents

コンパクトなガス分析装置及び方法 Download PDF

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JP7197369B2
JP7197369B2 JP2018564249A JP2018564249A JP7197369B2 JP 7197369 B2 JP7197369 B2 JP 7197369B2 JP 2018564249 A JP2018564249 A JP 2018564249A JP 2018564249 A JP2018564249 A JP 2018564249A JP 7197369 B2 JP7197369 B2 JP 7197369B2
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gas
separators
flow path
analyzer
detector
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JP2019520567A (ja
JP2019520567A5 (enExample
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タマラ マセア エリザベス ナイセン
ヨハネス ウェダ
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Koninklijke Philips NV
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6034—Construction of the column joining multiple columns
    • G01N30/6039—Construction of the column joining multiple columns in series
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • G01N30/463—Flow patterns using more than one column with serial coupling of separation columns for multidimensional chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • G01N30/465—Flow patterns using more than one column with serial coupling of separation columns with specially adapted interfaces between the columns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/466—Flow patterns using more than one column with separation columns in parallel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/468—Flow patterns using more than one column involving switching between different column configurations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/0004—Gaseous mixtures, e.g. polluted air
    • G01N33/0009—General constructional details of gas analysers, e.g. portable test equipment
    • G01N33/0027—General constructional details of gas analysers, e.g. portable test equipment concerning the detector
    • G01N33/0036—General constructional details of gas analysers, e.g. portable test equipment concerning the detector specially adapted to detect a particular component
    • G01N33/0047—Organic compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • G01N33/4975—Physical analysis of biological material of gaseous biological material, e.g. breath other than oxygen, carbon dioxide or alcohol, e.g. organic vapours
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N2030/0095—Separation specially adapted for use outside laboratory, e.g. field sampling, portable equipments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/025—Gas chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N2030/628—Multiplexing, i.e. several columns sharing a single detector
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/884—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample organic compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6034—Construction of the column joining multiple columns
    • G01N30/6043—Construction of the column joining multiple columns in parallel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/78—Detectors specially adapted therefor using more than one detector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Combustion & Propulsion (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
JP2018564249A 2016-06-17 2017-06-12 コンパクトなガス分析装置及び方法 Active JP7197369B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662351342P 2016-06-17 2016-06-17
US62/351,342 2016-06-17
PCT/EP2017/064210 WO2017216079A1 (en) 2016-06-17 2017-06-12 Compact gas analysis device and method

Publications (3)

Publication Number Publication Date
JP2019520567A JP2019520567A (ja) 2019-07-18
JP2019520567A5 JP2019520567A5 (enExample) 2020-07-02
JP7197369B2 true JP7197369B2 (ja) 2022-12-27

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US (1) US11016066B2 (enExample)
EP (1) EP3472610B1 (enExample)
JP (1) JP7197369B2 (enExample)
CN (1) CN109313173B (enExample)
ES (1) ES2970505T3 (enExample)
PL (1) PL3472610T3 (enExample)
WO (1) WO2017216079A1 (enExample)

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CN113167769B (zh) * 2018-11-28 2024-01-30 皇家飞利浦有限公司 具有过载检测的气体分析采样
US11020042B2 (en) * 2019-05-15 2021-06-01 Know Biological, Inc. Seizure detection device
TWI772776B (zh) * 2020-04-09 2022-08-01 美商艾諾斯股份有限公司 肺炎偵測裝置
US12320787B2 (en) * 2020-06-22 2025-06-03 Waters Technologies Corporation Insulated serial column chromatography arrangements and systems
CN113504231B (zh) * 2021-02-10 2024-07-19 北京朗观视觉科技有限公司 一种手持式尾气检测装置
US12360101B2 (en) * 2021-10-01 2025-07-15 Nicholas Grant Electronic systems and methods for health analysis from breath

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JP2002181799A (ja) 2000-10-18 2002-06-26 Agilent Technol Inc 多層ガスクロマトグラフ
US20050063865A1 (en) 2002-09-27 2005-03-24 Ulrich Bonne Phased VII micro fluid analyzer having a modular structure
JP2005221341A (ja) 2004-02-04 2005-08-18 Horiba Ltd 揮発性有機化合物測定装置
JP2009008402A (ja) 2007-06-26 2009-01-15 Shimadzu Corp マルチディメンジョナルガスクロマトグラフ装置
JP2009036739A (ja) 2007-08-06 2009-02-19 Hitachi Ltd 質量分析装置及び質量分析方法
JP2010271241A (ja) 2009-05-22 2010-12-02 Shimadzu Corp マルチディメンジョナルガスクロマトグラフ装置
US20110005300A1 (en) 2009-07-07 2011-01-13 Tricorntech Corporation CASCADED GAS CHROMATOGRAPHS (CGCs) WITH INDIVIDUAL TEMPERATURE CONTROL AND GAS ANALYSIS SYSTEMS USING SAME
JP2011112603A (ja) 2009-11-30 2011-06-09 Shimadzu Corp マルチディメンジョナルガスクロマトグラフ装置
JP2014153075A (ja) 2013-02-05 2014-08-25 Shimadzu Corp ガス流路切替装置、ガス流路切替方法及びガス流路切替プログラム
US20140298990A1 (en) 2011-11-09 2014-10-09 The Regents Of The University Of Michigan Devices and methods for adaptive micro-gas chromatography

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JP2002181799A (ja) 2000-10-18 2002-06-26 Agilent Technol Inc 多層ガスクロマトグラフ
US20050063865A1 (en) 2002-09-27 2005-03-24 Ulrich Bonne Phased VII micro fluid analyzer having a modular structure
JP2005221341A (ja) 2004-02-04 2005-08-18 Horiba Ltd 揮発性有機化合物測定装置
JP2009008402A (ja) 2007-06-26 2009-01-15 Shimadzu Corp マルチディメンジョナルガスクロマトグラフ装置
JP2009036739A (ja) 2007-08-06 2009-02-19 Hitachi Ltd 質量分析装置及び質量分析方法
JP2010271241A (ja) 2009-05-22 2010-12-02 Shimadzu Corp マルチディメンジョナルガスクロマトグラフ装置
US20110005300A1 (en) 2009-07-07 2011-01-13 Tricorntech Corporation CASCADED GAS CHROMATOGRAPHS (CGCs) WITH INDIVIDUAL TEMPERATURE CONTROL AND GAS ANALYSIS SYSTEMS USING SAME
JP2011112603A (ja) 2009-11-30 2011-06-09 Shimadzu Corp マルチディメンジョナルガスクロマトグラフ装置
US20140298990A1 (en) 2011-11-09 2014-10-09 The Regents Of The University Of Michigan Devices and methods for adaptive micro-gas chromatography
JP2014153075A (ja) 2013-02-05 2014-08-25 Shimadzu Corp ガス流路切替装置、ガス流路切替方法及びガス流路切替プログラム

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Publication number Publication date
US11016066B2 (en) 2021-05-25
EP3472610A1 (en) 2019-04-24
JP2019520567A (ja) 2019-07-18
ES2970505T3 (es) 2024-05-29
CN109313173A (zh) 2019-02-05
CN109313173B (zh) 2022-03-15
US20190331660A1 (en) 2019-10-31
EP3472610B1 (en) 2023-12-20
WO2017216079A1 (en) 2017-12-21
PL3472610T3 (pl) 2024-05-20

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