JP7175761B2 - 細胞培養装置、システム及びその使用方法 - Google Patents
細胞培養装置、システム及びその使用方法 Download PDFInfo
- Publication number
- JP7175761B2 JP7175761B2 JP2018512502A JP2018512502A JP7175761B2 JP 7175761 B2 JP7175761 B2 JP 7175761B2 JP 2018512502 A JP2018512502 A JP 2018512502A JP 2018512502 A JP2018512502 A JP 2018512502A JP 7175761 B2 JP7175761 B2 JP 7175761B2
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- Prior art keywords
- container
- cells
- lumen
- culturing cells
- cell
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/148—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/281—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
- A61M5/282—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by compression of deformable ampoule or carpule wall
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/24—Gas permeable parts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/26—Constructional details, e.g. recesses, hinges flexible
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/32—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Analytical Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021049742A JP7280907B2 (ja) | 2015-05-21 | 2021-03-24 | 細胞培養装置、システム及びその使用方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1508752.1 | 2015-05-21 | ||
| GBGB1508752.1A GB201508752D0 (en) | 2015-05-21 | 2015-05-21 | Cell culture device, system and methods of use thereof |
| PCT/GB2016/051451 WO2016185221A1 (en) | 2015-05-21 | 2016-05-20 | Cell culture device, system and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021049742A Division JP7280907B2 (ja) | 2015-05-21 | 2021-03-24 | 細胞培養装置、システム及びその使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018515144A JP2018515144A (ja) | 2018-06-14 |
| JPWO2016185221A5 JPWO2016185221A5 (enExample) | 2022-09-13 |
| JP7175761B2 true JP7175761B2 (ja) | 2022-11-21 |
Family
ID=53506153
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018512502A Active JP7175761B2 (ja) | 2015-05-21 | 2016-05-20 | 細胞培養装置、システム及びその使用方法 |
| JP2021049742A Active JP7280907B2 (ja) | 2015-05-21 | 2021-03-24 | 細胞培養装置、システム及びその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021049742A Active JP7280907B2 (ja) | 2015-05-21 | 2021-03-24 | 細胞培養装置、システム及びその使用方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US11208626B2 (enExample) |
| EP (1) | EP3298122A1 (enExample) |
| JP (2) | JP7175761B2 (enExample) |
| KR (2) | KR102587068B1 (enExample) |
| GB (1) | GB201508752D0 (enExample) |
| HK (1) | HK1253095A1 (enExample) |
| IL (1) | IL255790B2 (enExample) |
| WO (1) | WO2016185221A1 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201508752D0 (en) * | 2015-05-21 | 2015-07-01 | Mason Christopher And Veraitch Farlan S | Cell culture device, system and methods of use thereof |
| JP6965874B2 (ja) * | 2016-03-28 | 2021-11-10 | ソニーグループ株式会社 | 細胞培養方法 |
| JP6987080B2 (ja) | 2016-05-05 | 2021-12-22 | サウスウェスト リサーチ インスティテュート | 細胞増殖のための三次元バイオリアクター及び関連用途 |
| AU2017357650B2 (en) * | 2016-11-11 | 2023-07-13 | Oribiotech Ltd | Cell culture device system and methods of use thereof |
| JP2020528284A (ja) | 2017-09-01 | 2020-09-24 | ロンザ ウォーカーズヴィル,インコーポレーテッド | エンドツーエンド細胞療法の自動化 |
| US10696961B2 (en) | 2017-12-01 | 2020-06-30 | Global Life Sciences Solutions Usa Llc | Magnetic cell isolation techniques |
| JP6870629B2 (ja) * | 2018-02-09 | 2021-05-12 | Jfeエンジニアリング株式会社 | バイオリアクターバッグのスケールアップ方法 |
| US12331276B2 (en) | 2018-02-09 | 2025-06-17 | Global Life Sciences Solutions USA | Apparatus for fluid line management in a bioprocessing system |
| US10889792B2 (en) * | 2018-02-09 | 2021-01-12 | Global Life Sciences Solutions Usa Llc | Cell expansion vessel systems and methods |
| US11414639B2 (en) | 2018-02-09 | 2022-08-16 | Global Life Sciences Solutions Usa Llc | Bioprocessing vessel |
| US12077743B2 (en) | 2018-02-09 | 2024-09-03 | Global Life Sciences Solutions Usa Llc | Apparatus for fluid line management in a bioprocessing system |
| US11920119B2 (en) | 2018-02-09 | 2024-03-05 | Global Life Sciences Solutions Usa Llc | Systems and methods for bioprocessing |
| US11932842B2 (en) | 2018-02-09 | 2024-03-19 | Global Life Sciences Solutions Usa Llc | Bioprocessing apparatus |
| US11371007B2 (en) | 2018-02-09 | 2022-06-28 | Global Life Sciences Solutions Usa Llc | System and method for fluid flow management in a bioprocessing system |
| US12252682B2 (en) | 2018-02-09 | 2025-03-18 | Global Life Sciences Solutions Usa Llc | System and method for fluid flow management in a bioprocessing system |
| AU2019219291B2 (en) * | 2018-02-09 | 2024-11-14 | Global Life Sciences Solutions Usa Llc | Disposable kit for bioprocessing |
| US11149244B2 (en) | 2018-04-04 | 2021-10-19 | Southwest Research Institute | Three-dimensional bioreactor for T-cell activation and expansion for immunotherapy |
| US12203126B2 (en) | 2018-05-11 | 2025-01-21 | Exothera S.A. | System and method for clarifying a cell culture harvest solution |
| US11447731B2 (en) | 2018-09-24 | 2022-09-20 | Southwest Research Institute | Three-dimensional bioreactors |
| CN112752847B (zh) | 2018-09-28 | 2025-03-28 | 奥克泰生物科技股份有限公司 | 磁性分离 |
| CA3123314A1 (en) | 2018-12-21 | 2020-06-25 | Octane Biotech Inc. | Carousel for modular biologic production units |
| EP3898994A4 (en) | 2018-12-21 | 2022-12-14 | Lonza Walkersville, Inc. | AUTOMATED VIRAL VECTOR PRODUCTION |
| CN119685160A (zh) | 2018-12-28 | 2025-03-25 | 奥克泰生物科技股份有限公司 | 具有受控环境区的细胞培养和组织工程系统 |
| CA3125250A1 (en) * | 2019-01-04 | 2020-07-09 | Oribiotech Ltd | Cell processing unit, cell processing system and methods of use thereof |
| US12024699B2 (en) * | 2019-01-04 | 2024-07-02 | Oribiotech Ltd. | Systems, devices, and methods for cell processing |
| CN113498432A (zh) | 2019-02-08 | 2021-10-12 | 隆萨沃克斯维尔股份有限公司 | 用于自动化生物反应器的细胞浓缩方法和装置 |
| CA3288039A1 (en) * | 2019-02-25 | 2025-11-29 | University Of Maryland, Baltimore County | Adjustable fermentation and cell culture flasks |
| CN113874488B (zh) * | 2019-06-10 | 2024-11-05 | 爱平世股份有限公司 | 红细胞除去装置、单核细胞回收器、细胞培养装置、细胞培养系统 |
| JP7343881B2 (ja) * | 2019-06-10 | 2023-09-13 | アイ ピース,インコーポレイテッド | 赤血球除去装置、単核球回収器、細胞培養装置、細胞培養システム、細胞培養方法、及び単核球の回収方法 |
| WO2020262354A1 (ja) * | 2019-06-28 | 2020-12-30 | アイ ピース, インコーポレイテッド | 細胞培養器及び細胞培養装置 |
| EP3770600B1 (en) * | 2019-07-25 | 2023-05-10 | CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Développement | Purification process for cells |
| CN114787331A (zh) * | 2019-09-10 | 2022-07-22 | Emd密理博公司 | 铰接式生物容器 |
| WO2021081170A1 (en) | 2019-10-24 | 2021-04-29 | Octane Biotech Inc. | Cell culture chamber with improved cell-contacting surfaces |
| KR20220097457A (ko) | 2019-11-11 | 2022-07-07 | 론자 워커스빌 아이엔씨. | 자동화된 세포 처리를 위한 품질 관리 방법 |
| GB2592566B8 (en) | 2020-01-13 | 2025-08-13 | Oribiotech Ltd | An apparatus for, and a method of, processing cells |
| CA3172354A1 (en) * | 2020-03-09 | 2021-09-16 | Oribiotech Ltd | Cell culture container |
| CN111440720A (zh) * | 2020-04-17 | 2020-07-24 | 海口健康岛生物科技有限公司 | 一种免疫细胞培养装置 |
| CN116867886A (zh) * | 2020-09-01 | 2023-10-10 | 斯多怡科生物股份有限公司 | 细胞培养溶液容器和分配器 |
| US20240110152A1 (en) * | 2020-12-31 | 2024-04-04 | Iovance Biotherapeutics, Inc. | Devices and processes for automated production of tumor infiltrating lymphocytes |
| GB2609648B (en) * | 2021-08-12 | 2023-11-01 | Oribiotech Ltd | A culture device |
| GB2623112A (en) * | 2022-10-07 | 2024-04-10 | Oribiotech Ltd | A device |
| US12405283B1 (en) | 2024-08-16 | 2025-09-02 | Hyperius Biotech Inc | HLAB automation and related systems and methods |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005037984A1 (ja) | 2003-10-20 | 2005-04-28 | Jms Co., Ltd. | 細胞取扱装置、組織再生用組成物及び組織再生方法 |
| JP2007511205A (ja) | 2003-10-08 | 2007-05-10 | ウィルソン ウォルフ マニュファクチャリング コーポレイション | 気体透過性物質を利用する細胞を培養する方法及び装置 |
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| GB1232407A (enExample) * | 1968-08-30 | 1971-05-19 | ||
| US3712295A (en) | 1970-08-03 | 1973-01-23 | W Kline | Centrifuge tube |
| JPS5287290A (en) * | 1976-01-08 | 1977-07-20 | Kiyouko Takeuchi | Fermentation tank |
| US4867172A (en) | 1988-02-23 | 1989-09-19 | Habley Medical Technology Corporation | Collapsible blood collector |
| US5399493A (en) * | 1989-06-15 | 1995-03-21 | The Regents Of The University Of Michigan | Methods and compositions for the optimization of human hematopoietic progenitor cell cultures |
| US5209372A (en) * | 1992-04-08 | 1993-05-11 | Norwood Peter M | Collapsible spiral container |
| JPH0870847A (ja) * | 1994-09-02 | 1996-03-19 | Sumitomo Bakelite Co Ltd | 細胞浮遊培養用容器 |
| AU2002367057B2 (en) * | 2001-12-21 | 2007-01-11 | Organogenesis Inc. | Chamber with adjustable volume for cell culture and organ assist |
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| WO2008088371A2 (en) | 2006-06-16 | 2008-07-24 | Xcellerex, Inc. | Gas delivery configurations, foam control systems, and bag molding methods and articles for collapsible bag vessels and bioreactors |
| US8025173B2 (en) | 2006-09-07 | 2011-09-27 | Allegiance Corporation | Collapsible canister liner for medical fluid collection |
| WO2009139703A1 (en) * | 2008-05-15 | 2009-11-19 | Ge Healthcare Bio-Sciences Ab | Method for cell expansion |
| US8956860B2 (en) * | 2009-12-08 | 2015-02-17 | Juan F. Vera | Methods of cell culture for adoptive cell therapy |
| US8641641B2 (en) * | 2010-05-11 | 2014-02-04 | Ethicon Endo-Surgery, Inc. | Instrument for applying therapeutic cells, with proximal portion for processing therapeutic cells |
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| US9469671B2 (en) * | 2011-09-03 | 2016-10-18 | Therapeutic Proteins International, LLC | Closed bioreactor |
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| GB2581749B (en) * | 2013-12-20 | 2021-03-03 | Harvard College | Organomimetic devices and methods of use and manufacturing thereof |
| US10266940B2 (en) * | 2015-02-23 | 2019-04-23 | Applied Materials, Inc. | Auto capacitance tuner current compensation to control one or more film properties through target life |
| GB201508752D0 (en) * | 2015-05-21 | 2015-07-01 | Mason Christopher And Veraitch Farlan S | Cell culture device, system and methods of use thereof |
-
2015
- 2015-05-21 GB GBGB1508752.1A patent/GB201508752D0/en not_active Ceased
-
2016
- 2016-05-20 HK HK18112482.0A patent/HK1253095A1/zh unknown
- 2016-05-20 JP JP2018512502A patent/JP7175761B2/ja active Active
- 2016-05-20 EP EP16725209.7A patent/EP3298122A1/en active Pending
- 2016-05-20 IL IL255790A patent/IL255790B2/en unknown
- 2016-05-20 US US15/575,105 patent/US11208626B2/en active Active
- 2016-05-20 WO PCT/GB2016/051451 patent/WO2016185221A1/en not_active Ceased
- 2016-05-20 KR KR1020177036831A patent/KR102587068B1/ko active Active
- 2016-05-20 KR KR1020237020698A patent/KR102658422B1/ko active Active
-
2020
- 2020-12-18 US US17/127,255 patent/US11884911B2/en active Active
-
2021
- 2021-03-24 JP JP2021049742A patent/JP7280907B2/ja active Active
-
2023
- 2023-12-19 US US18/545,965 patent/US12344832B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007511205A (ja) | 2003-10-08 | 2007-05-10 | ウィルソン ウォルフ マニュファクチャリング コーポレイション | 気体透過性物質を利用する細胞を培養する方法及び装置 |
| WO2005037984A1 (ja) | 2003-10-20 | 2005-04-28 | Jms Co., Ltd. | 細胞取扱装置、組織再生用組成物及び組織再生方法 |
Non-Patent Citations (1)
| Title |
|---|
| 2013 Catalogue, Adhesive Dispensing Ltd, 2013年,[検索日 2021.07.06],インターネット<URL:http://pdfs.findtheneedle.co.uk/24913.pdf> |
Also Published As
| Publication number | Publication date |
|---|---|
| US20180142200A1 (en) | 2018-05-24 |
| IL255790A (en) | 2018-01-31 |
| WO2016185221A1 (en) | 2016-11-24 |
| KR102587068B1 (ko) | 2023-10-10 |
| IL255790B1 (en) | 2023-09-01 |
| US11208626B2 (en) | 2021-12-28 |
| US11884911B2 (en) | 2024-01-30 |
| KR20230104742A (ko) | 2023-07-10 |
| US20210130765A1 (en) | 2021-05-06 |
| JP7280907B2 (ja) | 2023-05-24 |
| JP2018515144A (ja) | 2018-06-14 |
| US12344832B2 (en) | 2025-07-01 |
| EP3298122A1 (en) | 2018-03-28 |
| JP2021106591A (ja) | 2021-07-29 |
| KR20180011216A (ko) | 2018-01-31 |
| US20240182844A1 (en) | 2024-06-06 |
| HK1253095A1 (zh) | 2019-06-06 |
| GB201508752D0 (en) | 2015-07-01 |
| IL255790B2 (en) | 2024-01-01 |
| KR102658422B1 (ko) | 2024-04-16 |
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