IL255790B2 - Cell culture device, system and methods of use thereof - Google Patents

Cell culture device, system and methods of use thereof

Info

Publication number
IL255790B2
IL255790B2 IL255790A IL25579017A IL255790B2 IL 255790 B2 IL255790 B2 IL 255790B2 IL 255790 A IL255790 A IL 255790A IL 25579017 A IL25579017 A IL 25579017A IL 255790 B2 IL255790 B2 IL 255790B2
Authority
IL
Israel
Prior art keywords
container
cells
culturing cells
lumen
section
Prior art date
Application number
IL255790A
Other languages
English (en)
Hebrew (he)
Other versions
IL255790A (en
IL255790B1 (en
Original Assignee
Oribiotech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oribiotech Ltd filed Critical Oribiotech Ltd
Publication of IL255790A publication Critical patent/IL255790A/en
Publication of IL255790B1 publication Critical patent/IL255790B1/en
Publication of IL255790B2 publication Critical patent/IL255790B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/26—Constructional details, e.g. recesses, hinges flexible
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/148—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/281—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
    • A61M5/282—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by compression of deformable ampoule or carpule wall
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/24—Gas permeable parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/32—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL255790A 2015-05-21 2016-05-20 Cell culture device, system and methods of use thereof IL255790B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1508752.1A GB201508752D0 (en) 2015-05-21 2015-05-21 Cell culture device, system and methods of use thereof
PCT/GB2016/051451 WO2016185221A1 (en) 2015-05-21 2016-05-20 Cell culture device, system and methods of use thereof

Publications (3)

Publication Number Publication Date
IL255790A IL255790A (en) 2018-01-31
IL255790B1 IL255790B1 (en) 2023-09-01
IL255790B2 true IL255790B2 (en) 2024-01-01

Family

ID=53506153

Family Applications (1)

Application Number Title Priority Date Filing Date
IL255790A IL255790B2 (en) 2015-05-21 2016-05-20 Cell culture device, system and methods of use thereof

Country Status (8)

Country Link
US (3) US11208626B2 (enExample)
EP (1) EP3298122A1 (enExample)
JP (2) JP7175761B2 (enExample)
KR (2) KR102587068B1 (enExample)
GB (1) GB201508752D0 (enExample)
HK (1) HK1253095A1 (enExample)
IL (1) IL255790B2 (enExample)
WO (1) WO2016185221A1 (enExample)

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GB201508752D0 (en) * 2015-05-21 2015-07-01 Mason Christopher And Veraitch Farlan S Cell culture device, system and methods of use thereof
WO2017169259A1 (ja) * 2016-03-28 2017-10-05 ソニー株式会社 細胞培養容器、細胞培養システム、細胞培養キット及び細胞培養方法
US10988724B2 (en) 2016-05-05 2021-04-27 Southwest Research Institute Three-dimensional bioreactor for cell expansion and related applications
US11993765B2 (en) 2016-11-11 2024-05-28 Silicon Valley Bank Uk Limited Cell culture device system and methods of use thereof
US11447745B2 (en) 2017-09-01 2022-09-20 Lonza Walkersville, Inc. End-to-end cell therapy automation
US10696961B2 (en) 2017-12-01 2020-06-30 Global Life Sciences Solutions Usa Llc Magnetic cell isolation techniques
US11371007B2 (en) 2018-02-09 2022-06-28 Global Life Sciences Solutions Usa Llc System and method for fluid flow management in a bioprocessing system
US12077743B2 (en) 2018-02-09 2024-09-03 Global Life Sciences Solutions Usa Llc Apparatus for fluid line management in a bioprocessing system
WO2019155026A1 (en) * 2018-02-09 2019-08-15 General Electric Company Systems and methods for bioprocessing
US11920119B2 (en) 2018-02-09 2024-03-05 Global Life Sciences Solutions Usa Llc Systems and methods for bioprocessing
US11414639B2 (en) 2018-02-09 2022-08-16 Global Life Sciences Solutions Usa Llc Bioprocessing vessel
US11932842B2 (en) 2018-02-09 2024-03-19 Global Life Sciences Solutions Usa Llc Bioprocessing apparatus
US12252682B2 (en) 2018-02-09 2025-03-18 Global Life Sciences Solutions Usa Llc System and method for fluid flow management in a bioprocessing system
JP6870629B2 (ja) * 2018-02-09 2021-05-12 Ｊｆｅエンジニアリング株式会社 バイオリアクターバッグのスケールアップ方法
US10889792B2 (en) * 2018-02-09 2021-01-12 Global Life Sciences Solutions Usa Llc Cell expansion vessel systems and methods
US12331276B2 (en) 2018-02-09 2025-06-17 Global Life Sciences Solutions USA Apparatus for fluid line management in a bioprocessing system
US11149244B2 (en) 2018-04-04 2021-10-19 Southwest Research Institute Three-dimensional bioreactor for T-cell activation and expansion for immunotherapy
WO2019215344A2 (en) * 2018-05-11 2019-11-14 Univercells Nv System and method for clarifying a cell culture harvest solution
SG11202102986XA (en) 2018-09-24 2021-04-29 Southwest Res Inst Three-dimensional bioreactors
CN112752847B (zh) 2018-09-28 2025-03-28 奥克泰生物科技股份有限公司 磁性分离
SG11202106384YA (en) 2018-12-21 2021-07-29 Octane Biotech Inc Carousel for modular biologic production units
KR20210108406A (ko) 2018-12-21 2021-09-02 론자 워커스빌 아이엔씨. 바이러스 벡터의 자동화된 생산
CN119685160A (zh) 2018-12-28 2025-03-25 奥克泰生物科技股份有限公司 具有受控环境区的细胞培养和组织工程系统
AU2020204795A1 (en) * 2019-01-04 2021-08-12 Oribiotech Ltd Cell processing platform cell processing system and methods of use thereof
US12024699B2 (en) * 2019-01-04 2024-07-02 Oribiotech Ltd. Systems, devices, and methods for cell processing
KR20210125510A (ko) 2019-02-08 2021-10-18 론자 워커스빌 아이엔씨. 자동화 생물반응기에서 사용하기 위한 세포 농축 방법 및 장치
CA3288039A1 (en) * 2019-02-25 2025-11-29 University Of Maryland, Baltimore County Adjustable fermentation and cell culture flasks
CN113785049B (zh) 2019-06-10 2025-11-25 爱平世股份有限公司 细胞培养方法及单核细胞的回收方法
EP3981446A4 (en) * 2019-06-10 2023-07-12 I Peace, Inc. DEVICE FOR REMOVING RED BLOOD CELLS, MONONUCLEAR CELL COLLECTOR, CELL CULTURE DEVICE, CELL CULTURE SYSTEM, CELL CULTURE PROCEDURE AND COLLECTION PROCEDURE FOR MONONUCLEAR CELLS
WO2020262354A1 (ja) * 2019-06-28 2020-12-30 アイ ピース， インコーポレイテッド 細胞培養器及び細胞培養装置
EP3770600B1 (en) * 2019-07-25 2023-05-10 CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Développement Purification process for cells
JP7566914B2 (ja) * 2019-09-10 2024-10-15 イー・エム・デイー・ミリポア・コーポレイシヨン 関節式バイオコンテナ
CN114729292A (zh) 2019-10-24 2022-07-08 奥克泰生物科技股份有限公司 具有经改进的细胞接触表面的细胞培养室
WO2021096850A1 (en) 2019-11-11 2021-05-20 Lonza Walkersville, Inc. Quality control methods for automated cell processing
GB2592566B8 (en) 2020-01-13 2025-08-13 Oribiotech Ltd An apparatus for, and a method of, processing cells
WO2021181080A1 (en) * 2020-03-09 2021-09-16 Oribiotech Ltd Cell culture container
CN111440720A (zh) * 2020-04-17 2020-07-24 海口健康岛生物科技有限公司 一种免疫细胞培养装置
CN116867886A (zh) * 2020-09-01 2023-10-10 斯多怡科生物股份有限公司 细胞培养溶液容器和分配器
US20240110152A1 (en) * 2020-12-31 2024-04-04 Iovance Biotherapeutics, Inc. Devices and processes for automated production of tumor infiltrating lymphocytes
GB2609648B (en) * 2021-08-12 2023-11-01 Oribiotech Ltd A culture device
GB2623112A (en) * 2022-10-07 2024-04-10 Oribiotech Ltd A device
US12405283B1 (en) 2024-08-16 2025-09-02 Hyperius Biotech Inc HLAB automation and related systems and methods

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GB1232407A (enExample) * 1968-08-30 1971-05-19
US3712295A (en) * 1970-08-03 1973-01-23 W Kline Centrifuge tube
US20070254356A1 (en) * 2003-10-08 2007-11-01 Wilson Wolf Manufacturing Corporation Cell culture methods and devices utilizing gas permeable materials
EP1679365A1 (en) * 2003-10-20 2006-07-12 JMS Co., Ltd. Cell handling device, human tissue regeneration composition, and human tissue regeneration method
US20070224676A1 (en) * 2006-03-21 2007-09-27 Becton, Dickinson And Company Expandable culture roller bottle
WO2013021079A1 (es) * 2011-08-08 2013-02-14 Beltran Gil Mario Jeringuilla hipodérmica con sistema de fuelle
US20130281940A1 (en) * 2012-04-20 2013-10-24 Medrad, Inc. Bellows Syringe Fluid Delivery System

Also Published As

Publication number Publication date
US20240182844A1 (en) 2024-06-06
IL255790A (en) 2018-01-31
HK1253095A1 (zh) 2019-06-06
KR20230104742A (ko) 2023-07-10
JP7175761B2 (ja) 2022-11-21
KR102658422B1 (ko) 2024-04-16
US12344832B2 (en) 2025-07-01
JP7280907B2 (ja) 2023-05-24
EP3298122A1 (en) 2018-03-28
IL255790B1 (en) 2023-09-01
WO2016185221A1 (en) 2016-11-24
US20180142200A1 (en) 2018-05-24
KR20180011216A (ko) 2018-01-31
US20210130765A1 (en) 2021-05-06
GB201508752D0 (en) 2015-07-01
JP2018515144A (ja) 2018-06-14
US11884911B2 (en) 2024-01-30
KR102587068B1 (ko) 2023-10-10
US11208626B2 (en) 2021-12-28
JP2021106591A (ja) 2021-07-29

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