JP7170331B2 - 固形及び血液癌の治療のための併用療法 - Google Patents

固形及び血液癌の治療のための併用療法 Download PDF

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JP7170331B2
JP7170331B2 JP2019551449A JP2019551449A JP7170331B2 JP 7170331 B2 JP7170331 B2 JP 7170331B2 JP 2019551449 A JP2019551449 A JP 2019551449A JP 2019551449 A JP2019551449 A JP 2019551449A JP 7170331 B2 JP7170331 B2 JP 7170331B2
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cells
human
cancer
seq
amino acid
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JP2020511481A (ja
JP2020511481A5 (enExample
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マニング，パメラ，ティー．
プロ，ロビン
アルマグロ，ジュアン，シー．
カー，ロバート，ダブリュ．
カポッチャ，ベンジャミン，ジェイ．
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Arch Oncology Inc
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Arch Oncology Inc
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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JP2019551449A 2017-03-22 2018-03-22 固形及び血液癌の治療のための併用療法 Expired - Fee Related JP7170331B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762475032P 2017-03-22 2017-03-22
US201762475036P 2017-03-22 2017-03-22
US62/475,036 2017-03-22
US62/475,032 2017-03-22
US15/871,802 US20180142019A1 (en) 2016-10-21 2018-01-15 Therapeutic cd47 antibodies
US15/871,802 2018-01-15
PCT/US2018/023860 WO2018175790A1 (en) 2017-03-22 2018-03-22 Combination therapy for the treatment of solid and hematological cancers

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JP2020511481A JP2020511481A (ja) 2020-04-16
JP2020511481A5 JP2020511481A5 (enExample) 2021-05-06
JP7170331B2 true JP7170331B2 (ja) 2022-11-14

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EP (1) EP3600393A4 (enExample)
JP (1) JP7170331B2 (enExample)
CN (1) CN111148535A (enExample)
AU (1) AU2018240377A1 (enExample)
CA (1) CA3057139A1 (enExample)
SG (1) SG11201908602UA (enExample)
WO (1) WO2018175790A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9221908B2 (en) 2012-12-12 2015-12-29 Vasculox, Inc. Therapeutic CD47 antibodies
MX2015007446A (es) 2012-12-12 2015-12-07 Vasculox Inc Anticuerpos terapeuticos para cd47.
CN116425875A (zh) 2015-09-18 2023-07-14 安驰肿瘤公司 治疗性cd47抗体
EP3529276A4 (en) 2016-10-21 2020-06-17 Arch Oncology, Inc. CD47 THERAPEUTIC ANTIBODIES
CN113166257B (zh) * 2018-12-03 2023-05-30 上海开拓者生物医药有限公司 Cd47抗体及其制备方法和应用
JP2022532249A (ja) * 2019-05-16 2022-07-13 アーチ オンコロジー，インコーポレイテッド インターロイキンタンパク質の類似体と組み合わせて癌を処置するための治療用組成物及び方法
EP3980747A1 (en) 2019-06-07 2022-04-13 ALX Oncology Inc. Methods and reagents for reducing the interference of drugs that bind cd47 in serological assays
WO2021080920A2 (en) * 2019-10-23 2021-04-29 Arch Oncology, Inc. Combination therapy for the treatment of solid and hematological cancers
JP7369297B2 (ja) 2019-12-17 2023-10-25 ファイザー・インク Ｃｄ４７、ｐｄ－ｌ１に特異的な抗体、およびその使用
CN120040592A (zh) * 2020-07-31 2025-05-27 百奥泰生物制药股份有限公司 Cd47抗体及其应用
WO2022120286A1 (en) 2020-12-06 2022-06-09 ALX Oncology Inc. Multimers for reducing the interference of drugs that bind cd47 in serological assays

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JP2015508072A (ja) 2012-02-06 2015-03-16 インヒブルクス エルエルシーＩｎｈｉｂｒｘ Ｌｌｃ Ｃｄ４７抗体及びその使用方法
JP2016507555A (ja) 2013-02-06 2016-03-10 インヒブルクス エルピー 血小板非減少性かつ赤血球非減少性ｃｄ４７抗体及びその使用方法

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JP4637749B2 (ja) * 2003-11-11 2011-02-23 中外製薬株式会社 ヒト化抗ｃｄ４７抗体
PT2242773T (pt) * 2008-02-11 2017-09-15 Cure Tech Ltd Anticorpos monoclonais para o tratamento de tumores
MX2012008383A (es) * 2010-01-21 2012-11-23 Immunogen Inc Composiciones y metodos para el tratamiento de cancer de ovario.
EP2744830A4 (en) * 2012-06-21 2015-06-17 Compugen Ltd LSR ANTIBODIES AND USES THEREOF FOR THE TREATMENT OF CANCER
US9221908B2 (en) * 2012-12-12 2015-12-29 Vasculox, Inc. Therapeutic CD47 antibodies
CN116425875A (zh) * 2015-09-18 2023-07-14 安驰肿瘤公司 治疗性cd47抗体

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JP2015508072A (ja) 2012-02-06 2015-03-16 インヒブルクス エルエルシーＩｎｈｉｂｒｘ Ｌｌｃ Ｃｄ４７抗体及びその使用方法
JP2016507555A (ja) 2013-02-06 2016-03-10 インヒブルクス エルピー 血小板非減少性かつ赤血球非減少性ｃｄ４７抗体及びその使用方法

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Cancer Res. (2016) vol.76, issue 14, suppl., Abstract 4001,<https://aacrjournals.org/cancerres/article/76/14_Supplement/4001/611236/Abstract-4001-The-anti-CD47-antibody-Hu5F9-G4>
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Nat. Med. (2015) vol.21, no.10, p.1209-1215, Supplementary Information
PLoS One (2015) vol.10, issue 9, e0137345, p.1-23

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CN111148535A (zh) 2020-05-12
EP3600393A4 (en) 2020-12-23
EP3600393A1 (en) 2020-02-05
SG11201908602UA (en) 2019-10-30
JP2020511481A (ja) 2020-04-16
CA3057139A1 (en) 2018-09-27
AU2018240377A1 (en) 2019-10-31
WO2018175790A1 (en) 2018-09-27

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