CN111148535A - 治疗实体癌和血液癌的组合疗法 - Google Patents

治疗实体癌和血液癌的组合疗法 Download PDF

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Publication number
CN111148535A
CN111148535A CN201880028490.2A CN201880028490A CN111148535A CN 111148535 A CN111148535 A CN 111148535A CN 201880028490 A CN201880028490 A CN 201880028490A CN 111148535 A CN111148535 A CN 111148535A
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seq
amino acid
acid sequence
cells
light chain
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P·T·曼宁
R·普罗
J·C·阿尔马格罗
R·W·卡尔
B·J·卡波恰
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Anchi Oncology
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Anchi Oncology
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Priority claimed from US15/871,802 external-priority patent/US20180142019A1/en
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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CN201880028490.2A 2017-03-22 2018-03-22 治疗实体癌和血液癌的组合疗法 Pending CN111148535A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762475032P 2017-03-22 2017-03-22
US201762475036P 2017-03-22 2017-03-22
US62/475,036 2017-03-22
US62/475,032 2017-03-22
US15/871,802 US20180142019A1 (en) 2016-10-21 2018-01-15 Therapeutic cd47 antibodies
US15/871,802 2018-01-15
PCT/US2018/023860 WO2018175790A1 (en) 2017-03-22 2018-03-22 Combination therapy for the treatment of solid and hematological cancers

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Publication Number Publication Date
CN111148535A true CN111148535A (zh) 2020-05-12

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EP (1) EP3600393A4 (enExample)
JP (1) JP7170331B2 (enExample)
CN (1) CN111148535A (enExample)
AU (1) AU2018240377A1 (enExample)
CA (1) CA3057139A1 (enExample)
SG (1) SG11201908602UA (enExample)
WO (1) WO2018175790A1 (enExample)

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US9221908B2 (en) 2012-12-12 2015-12-29 Vasculox, Inc. Therapeutic CD47 antibodies
MX2015007446A (es) 2012-12-12 2015-12-07 Vasculox Inc Anticuerpos terapeuticos para cd47.
BR112018005322A2 (pt) 2015-09-18 2018-12-11 Arch Oncology, Inc. anticorpo monoclonal ou seu fragmento de ligação a antígenos, composição farmacêutica, anticorpo monoclonal ou seu fragmento de ligação a antígenos para uso, método de tratamento de lesão de isquemia-reperfusão, método de tratamento de câncer em um paciente humano, método de avaliação da expressão de cd47 em células tumorais e/ou imunes usando um anticorpo monoclonal ou seu fragmento de ligação a antígenos
EP3529276A4 (en) 2016-10-21 2020-06-17 Arch Oncology, Inc. CD47 THERAPEUTIC ANTIBODIES
CN113166257B (zh) * 2018-12-03 2023-05-30 上海开拓者生物医药有限公司 Cd47抗体及其制备方法和应用
JP2022532249A (ja) * 2019-05-16 2022-07-13 アーチ オンコロジー,インコーポレイテッド インターロイキンタンパク質の類似体と組み合わせて癌を処置するための治療用組成物及び方法
JP7561775B2 (ja) 2019-06-07 2024-10-04 エーエルエックス オンコロジー インコーポレイテッド 血清学的アッセイにおいてcd47に結合する薬物の干渉を低減するための方法及び試薬
AU2020372327A1 (en) * 2019-10-23 2022-06-02 Arch Oncology, Inc. Combination therapy for the treatment of solid and hematological cancers
PE20230160A1 (es) 2019-12-17 2023-02-01 Pfizer Anticuerpos especificos para cd47, pd-l1 y sus usos
CN114057876B (zh) * 2020-07-31 2025-03-21 百奥泰生物制药股份有限公司 Cd47抗体及其应用
US20220196651A1 (en) 2020-12-06 2022-06-23 ALX Oncology Inc. Multimers for reducing the interference of drugs that bind cd47 in serological assays

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CN104271757A (zh) * 2012-02-06 2015-01-07 印希彼有限责任公司 Cd47抗体及其使用方法
US20160137733A1 (en) * 2012-12-12 2016-05-19 Vasculox Inc. Therapeutic cd47 antibodies
WO2017049251A2 (en) * 2015-09-18 2017-03-23 Tioma Therapeutics, Inc. Therapeutic cd47 antibodies

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CN104271757A (zh) * 2012-02-06 2015-01-07 印希彼有限责任公司 Cd47抗体及其使用方法
US20160137733A1 (en) * 2012-12-12 2016-05-19 Vasculox Inc. Therapeutic cd47 antibodies
WO2017049251A2 (en) * 2015-09-18 2017-03-23 Tioma Therapeutics, Inc. Therapeutic cd47 antibodies

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JP7170331B2 (ja) 2022-11-14
JP2020511481A (ja) 2020-04-16
AU2018240377A1 (en) 2019-10-31
EP3600393A1 (en) 2020-02-05
EP3600393A4 (en) 2020-12-23
SG11201908602UA (en) 2019-10-30
WO2018175790A1 (en) 2018-09-27
CA3057139A1 (en) 2018-09-27

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