AU2018240377A1 - Combination therapy for the treatment of solid and hematological cancers - Google Patents
Combination therapy for the treatment of solid and hematological cancers Download PDFInfo
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- AU2018240377A1 AU2018240377A1 AU2018240377A AU2018240377A AU2018240377A1 AU 2018240377 A1 AU2018240377 A1 AU 2018240377A1 AU 2018240377 A AU2018240377 A AU 2018240377A AU 2018240377 A AU2018240377 A AU 2018240377A AU 2018240377 A1 AU2018240377 A1 AU 2018240377A1
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- C07—ORGANIC CHEMISTRY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C07—ORGANIC CHEMISTRY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07—ORGANIC CHEMISTRY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C—CHEMISTRY; METALLURGY
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
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| US201762475036P | 2017-03-22 | 2017-03-22 | |
| US201762475032P | 2017-03-22 | 2017-03-22 | |
| US62/475,036 | 2017-03-22 | ||
| US62/475,032 | 2017-03-22 | ||
| US15/871,802 | 2018-01-15 | ||
| US15/871,802 US20180142019A1 (en) | 2016-10-21 | 2018-01-15 | Therapeutic cd47 antibodies |
| PCT/US2018/023860 WO2018175790A1 (en) | 2017-03-22 | 2018-03-22 | Combination therapy for the treatment of solid and hematological cancers |
Publications (1)
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| AU2018240377A1 true AU2018240377A1 (en) | 2019-10-31 |
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| AU2018240377A Abandoned AU2018240377A1 (en) | 2017-03-22 | 2018-03-22 | Combination therapy for the treatment of solid and hematological cancers |
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| JP (1) | JP7170331B2 (enExample) |
| CN (1) | CN111148535A (enExample) |
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| CA (1) | CA3057139A1 (enExample) |
| SG (1) | SG11201908602UA (enExample) |
| WO (1) | WO2018175790A1 (enExample) |
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| MX2015007446A (es) | 2012-12-12 | 2015-12-07 | Vasculox Inc | Anticuerpos terapeuticos para cd47. |
| US9221908B2 (en) | 2012-12-12 | 2015-12-29 | Vasculox, Inc. | Therapeutic CD47 antibodies |
| MX2018003374A (es) | 2015-09-18 | 2018-11-09 | Arch Oncology Inc | Anticuerpos terapeuticos cd47. |
| WO2018075960A1 (en) | 2016-10-21 | 2018-04-26 | Tioma Therapeutics, Inc. | Therapeutic cd47 antibodies |
| CN113166257B (zh) * | 2018-12-03 | 2023-05-30 | 上海开拓者生物医药有限公司 | Cd47抗体及其制备方法和应用 |
| JP2022532249A (ja) * | 2019-05-16 | 2022-07-13 | アーチ オンコロジー，インコーポレイテッド | インターロイキンタンパク質の類似体と組み合わせて癌を処置するための治療用組成物及び方法 |
| JP7561775B2 (ja) | 2019-06-07 | 2024-10-04 | エーエルエックス オンコロジー インコーポレイテッド | 血清学的アッセイにおいてｃｄ４７に結合する薬物の干渉を低減するための方法及び試薬 |
| AU2020372327A1 (en) * | 2019-10-23 | 2022-06-02 | Arch Oncology, Inc. | Combination therapy for the treatment of solid and hematological cancers |
| KR20220114049A (ko) | 2019-12-17 | 2022-08-17 | 화이자 인코포레이티드 | Cd47, pd-l1에 특이적인 항체, 및 그의 용도 |
| US20230303711A1 (en) * | 2020-07-31 | 2023-09-28 | Bio-Thera Solutions, Ltd. | Anti-cd47 antibody and use thereof |
| JP2023552375A (ja) | 2020-12-06 | 2023-12-15 | エーエルエックス オンコロジー インコーポレイテッド | 血清学的アッセイにおいてｃｄ４７に結合する薬物の干渉を低減するための多量体 |
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| US7696325B2 (en) * | 1999-03-10 | 2010-04-13 | Chugai Seiyaku Kabushiki Kaisha | Polypeptide inducing apoptosis |
| CN101133083A (zh) * | 2003-11-11 | 2008-02-27 | 中外制药株式会社 | 人源化的抗cd47抗体 |
| CA2715166C (en) * | 2008-02-11 | 2017-05-16 | Curetech Ltd. | Monoclonal antibodies for tumor treatment |
| BR112012017642A2 (pt) * | 2010-01-21 | 2016-04-12 | Immunogen Inc | composições e métodos para tratamento de câncer de ovário |
| US9045541B2 (en) * | 2012-02-06 | 2015-06-02 | Inhibrx Llc | CD47 antibodies and methods of use thereof |
| AU2013278843A1 (en) * | 2012-06-21 | 2014-03-27 | Compugen Ltd. | LSR antibodies, and uses thereof for treatment of cancer |
| US9221908B2 (en) * | 2012-12-12 | 2015-12-29 | Vasculox, Inc. | Therapeutic CD47 antibodies |
| NZ710695A (en) | 2013-02-06 | 2020-05-29 | Inhibrx Inc | Non-platelet depleting and non-red blood cell depleting cd47 antibodies and methods of use thereof |
| MX2018003374A (es) * | 2015-09-18 | 2018-11-09 | Arch Oncology Inc | Anticuerpos terapeuticos cd47. |
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| SG11201908602UA (en) | 2019-10-30 |
| EP3600393A1 (en) | 2020-02-05 |
| CA3057139A1 (en) | 2018-09-27 |
| CN111148535A (zh) | 2020-05-12 |
| JP7170331B2 (ja) | 2022-11-14 |
| WO2018175790A1 (en) | 2018-09-27 |
| JP2020511481A (ja) | 2020-04-16 |
| EP3600393A4 (en) | 2020-12-23 |
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