JP7117845B2 - タンパク質カプセル - Google Patents
タンパク質カプセル Download PDFInfo
- Publication number
- JP7117845B2 JP7117845B2 JP2017512974A JP2017512974A JP7117845B2 JP 7117845 B2 JP7117845 B2 JP 7117845B2 JP 2017512974 A JP2017512974 A JP 2017512974A JP 2017512974 A JP2017512974 A JP 2017512974A JP 7117845 B2 JP7117845 B2 JP 7117845B2
- Authority
- JP
- Japan
- Prior art keywords
- capsule
- proteins
- protein
- phase
- shell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4833—Encapsulating processes; Filling of capsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
- B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Biomedical Technology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1415681.4 | 2014-09-04 | ||
| GBGB1415681.4A GB201415681D0 (en) | 2014-09-04 | 2014-09-04 | Protien Capsules |
| PCT/EP2015/070300 WO2016034728A1 (en) | 2014-09-04 | 2015-09-04 | Protein capsules |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017527566A JP2017527566A (ja) | 2017-09-21 |
| JP2017527566A5 JP2017527566A5 (cg-RX-API-DMAC10.html) | 2018-09-27 |
| JP7117845B2 true JP7117845B2 (ja) | 2022-08-15 |
Family
ID=51796212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017512974A Active JP7117845B2 (ja) | 2014-09-04 | 2015-09-04 | タンパク質カプセル |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11878080B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP3188719B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP7117845B2 (cg-RX-API-DMAC10.html) |
| GB (1) | GB201415681D0 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2016034728A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201415681D0 (en) | 2014-09-04 | 2014-10-22 | Cambridge Entpr Ltd And President And Fellows Of Harvard College | Protien Capsules |
| SE541260C2 (en) * | 2016-05-17 | 2019-05-21 | Benjamin Schmuck | Antibody binding nanofibrils |
| US20210154359A1 (en) * | 2017-07-14 | 2021-05-27 | Hi-Aspect Limited | Fibrillar-protein based compositions and uses thereof |
| CN109044987A (zh) * | 2018-09-17 | 2018-12-21 | 青海清华博众生物技术有限公司 | 一种羟丙基淀粉空心胶囊及其制备方法 |
| CN111939312B (zh) * | 2020-07-03 | 2022-04-12 | 中国科学院大学温州研究院(温州生物材料与工程研究所) | 一种双重交联的多功能水凝胶敷料及其制备和用途 |
| CN115193496B (zh) * | 2022-07-18 | 2024-02-27 | 南昌大学 | 一种微流道装置和该装置制备的高载油微胶囊及其方法 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008535644A (ja) | 2005-03-04 | 2008-09-04 | プレジデント・アンド・フエローズ・オブ・ハーバード・カレツジ | 多重エマルジョンの形成のための方法および装置 |
| JP2009502492A (ja) | 2005-08-01 | 2009-01-29 | テッヒニシェ・ウニヴェルジテート・ミュンヘン | スパイダーシルクタンパク質からなるナノおよびマイクロカプセルの製造方法 |
| JP2010536381A (ja) | 2007-08-21 | 2010-12-02 | アフォミックス コーポレイション | 相互作用スクリーニングの方法、システムおよび装置 |
| US20110280944A1 (en) | 2010-05-17 | 2011-11-17 | Samuel Stupp | Fibrous microcapsules and methods of assembly and use thereof |
| WO2014118553A1 (en) | 2013-01-30 | 2014-08-07 | Cambridge Enterprise Limited | Nested supramolecular capsules |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5196183A (en) * | 1991-12-04 | 1993-03-23 | Sterling Winthrop Inc. | Contrast agents for ultrasound imaging |
| GB0028710D0 (en) * | 2000-11-24 | 2001-01-10 | Isis Innovation | Mixed fibrils |
| CN101018816A (zh) | 2004-04-23 | 2007-08-15 | 尤金妮亚·库马切瓦 | 生产具有选定尺寸、形状、形态和组成的聚合物颗粒的方法 |
| ATE503465T1 (de) * | 2004-10-25 | 2011-04-15 | Celonova Biosciences Germany Gmbh | Beladbare polyphosphazenhaltige teilchen für therapeutische und/oder diagnostische anwendungen sowie herstellungs- und verwendungsverfahren dafür |
| US20090273105A1 (en) * | 2005-05-23 | 2009-11-05 | Cornell Research Foundation | Method and system for performing an interfacial reaction in a microfluidic device |
| FR2893501B1 (fr) | 2005-11-21 | 2014-03-14 | Oreal | Compositions topiques pour favoriser l'homeostasie de la peau |
| US20070259382A1 (en) | 2005-11-22 | 2007-11-08 | The University Of Iowa Research Foundation | Rapid localized cell trapping on biodegradable polymers |
| WO2007082923A2 (de) * | 2006-01-20 | 2007-07-26 | Basf Se | Verwendung von protein-microbeads in der kosmetik |
| WO2007141131A1 (en) * | 2006-06-08 | 2007-12-13 | Technische Universitaet Muenchen | Microfluidic device for controlled aggregation of spider silk |
| US20100028451A1 (en) * | 2006-09-26 | 2010-02-04 | Trustees Of Tufts College | Silk microspheres for encapsulation and controlled release |
| WO2008108838A2 (en) | 2006-11-21 | 2008-09-12 | Charles Stark Draper Laboratory, Inc. | Microfluidic devices and methods for fabricating the same |
| WO2008106485A2 (en) | 2007-02-27 | 2008-09-04 | Trustees Of Tufts College | Tissue-engineered silk organs |
| CA2689427C (en) | 2007-06-05 | 2015-12-29 | Eugenia Kumacheva | Multiple continuous microfluidic reactors for the scaled up synthesis of gel or polymer particles |
| WO2009039458A2 (en) | 2007-09-19 | 2009-03-26 | Massachusetts Institute Of Technology | Virus/nanowire encapsulation within polymer microgels for 2d and 3d devices for energy and electronics |
| EP2307054A4 (en) | 2008-06-18 | 2013-02-06 | Tufts College | EDIBLE HOLOGRAPHIC SILK PRODUCTS |
| JP2011530491A (ja) * | 2008-08-08 | 2011-12-22 | ビーエーエスエフ ソシエタス・ヨーロピア | バイオポリマーに基づいた活性物質含有連続繊維層、その使用、およびその生産のための方法 |
| WO2010036992A2 (en) | 2008-09-26 | 2010-04-01 | Trustees Of Tufts College | Active silk muco-adhesives, silk electrogelation process, and devices |
| US8501172B2 (en) | 2008-09-26 | 2013-08-06 | Trustees Of Tufts College | pH-induced silk gels and uses thereof |
| US9603243B2 (en) | 2010-04-12 | 2017-03-21 | Tufts University | Silk electronic components |
| CA2839719A1 (en) | 2010-06-17 | 2011-12-22 | Tufts University / Trustees Of Tufts College | Silk optical particles and uses thereof |
| KR20140048067A (ko) * | 2010-08-26 | 2014-04-23 | 바스프 에스이 | 자기-조립형 단백질의 고 농축 용액의 제조 방법 |
| JP5937092B2 (ja) | 2010-10-19 | 2016-06-22 | トラスティーズ オブ タフツ カレッジ | シルクフィブロインベースのマイクロニードルおよびその製造方法 |
| US8546338B2 (en) * | 2010-12-08 | 2013-10-01 | Johnson & Johnson Consumer Companies, Inc. | Self-assembling hydrogels based on dicephalic peptide amphiphiles |
| WO2012145652A1 (en) | 2011-04-20 | 2012-10-26 | Trustees Of Tufts College | Dynamic silk coatings for implantable devices |
| BR112014001868B1 (pt) * | 2011-07-26 | 2022-01-11 | Cambridge Enterprise Limited | Cápsulas supramoleculares, método para preparação das referidas cápsulas e método não-terapêutico de distribuir um componente a um local |
| WO2013103424A2 (en) | 2011-10-11 | 2013-07-11 | Tufts University | Silk-based multifunctional biomedical platform |
| US20140370094A1 (en) | 2011-11-08 | 2014-12-18 | Tufts University | Silk-based scaffold platform for engineering tissue constructs |
| ES2953309T3 (es) | 2011-11-09 | 2023-11-10 | Tufts College | Partículas de fibroína de seda inyectables y usos de las mismas |
| WO2013071123A1 (en) | 2011-11-09 | 2013-05-16 | Trustees Of Tufts College | Injectable silk fibroin foams and uses thereof |
| CA2865796A1 (en) | 2011-12-29 | 2013-07-04 | Trustees Of Tufts College | Functionalization of biomaterials to control regeneration and inflammation responses |
| EP2625966A1 (en) * | 2012-02-13 | 2013-08-14 | Bionanoplus, S.L. | Nanoparticles comprising a vegetable hydrophobic protein and a water miscible non-volatile organic solvent and uses thereof |
| WO2013142119A1 (en) * | 2012-03-20 | 2013-09-26 | Trustees Of Tufts College | Silk reservoirs for drug delivery |
| WO2014012105A1 (en) * | 2012-07-13 | 2014-01-16 | Tufts University | Encapsulation of immiscible phases in silk fibroin biomaterials |
| US20140023688A1 (en) | 2012-07-13 | 2014-01-23 | Firmenich Sa | Encapsulated oils |
| CN105979938A (zh) * | 2013-12-09 | 2016-09-28 | 香港大学 | 用于包封粒子、胶体和细胞的芯-壳胶囊 |
| GB201415681D0 (en) | 2014-09-04 | 2014-10-22 | Cambridge Entpr Ltd And President And Fellows Of Harvard College | Protien Capsules |
-
2014
- 2014-09-04 GB GBGB1415681.4A patent/GB201415681D0/en not_active Ceased
-
2015
- 2015-09-04 EP EP15775633.9A patent/EP3188719B1/en active Active
- 2015-09-04 JP JP2017512974A patent/JP7117845B2/ja active Active
- 2015-09-04 US US15/508,876 patent/US11878080B2/en active Active
- 2015-09-04 WO PCT/EP2015/070300 patent/WO2016034728A1/en not_active Ceased
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008535644A (ja) | 2005-03-04 | 2008-09-04 | プレジデント・アンド・フエローズ・オブ・ハーバード・カレツジ | 多重エマルジョンの形成のための方法および装置 |
| JP2009502492A (ja) | 2005-08-01 | 2009-01-29 | テッヒニシェ・ウニヴェルジテート・ミュンヘン | スパイダーシルクタンパク質からなるナノおよびマイクロカプセルの製造方法 |
| JP2010536381A (ja) | 2007-08-21 | 2010-12-02 | アフォミックス コーポレイション | 相互作用スクリーニングの方法、システムおよび装置 |
| US20110280944A1 (en) | 2010-05-17 | 2011-11-17 | Samuel Stupp | Fibrous microcapsules and methods of assembly and use thereof |
| WO2014118553A1 (en) | 2013-01-30 | 2014-08-07 | Cambridge Enterprise Limited | Nested supramolecular capsules |
Also Published As
| Publication number | Publication date |
|---|---|
| GB201415681D0 (en) | 2014-10-22 |
| EP3188719B1 (en) | 2022-10-05 |
| US20170202779A1 (en) | 2017-07-20 |
| US11878080B2 (en) | 2024-01-23 |
| WO2016034728A1 (en) | 2016-03-10 |
| JP2017527566A (ja) | 2017-09-21 |
| EP3188719A1 (en) | 2017-07-12 |
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