JP7108036B2 - 細胞選択方法及び細胞代謝改変方法 - Google Patents

細胞選択方法及び細胞代謝改変方法 Download PDF

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JP7108036B2
JP7108036B2 JP2020536104A JP2020536104A JP7108036B2 JP 7108036 B2 JP7108036 B2 JP 7108036B2 JP 2020536104 A JP2020536104 A JP 2020536104A JP 2020536104 A JP2020536104 A JP 2020536104A JP 7108036 B2 JP7108036 B2 JP 7108036B2
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cells
cell
nucleic acid
p5cs
proline
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JP2021511781A (ja
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ロバート ヤン，
クリストファー， マーク スメールズ，
コリン， マーク ジェイクス，
アンドリュー， ジェイ． ラチャー，
ガーディープ シン，
ジェームズ バッジ，
ジョアン ロブール，
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Lonza AG
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    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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    • C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
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    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
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    • C12N9/0028—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5) with NAD or NADP as acceptor (1.5.1)
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    • C12Y105/01—Oxidoreductases acting on the CH-NH group of donors (1.5) with NAD+ or NADP+ as acceptor (1.5.1)
    • C12Y105/01012—1-Pyrroline-5-carboxylate dehydrogenase (1.5.1.12)
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JP2020536104A 2018-02-02 2019-02-01 細胞選択方法及び細胞代謝改変方法 Active JP7108036B2 (ja)

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JP2022112973A JP7404453B2 (ja) 2018-02-02 2022-07-14 細胞選択方法及び細胞代謝改変方法
JP2023210793A JP2024037889A (ja) 2018-02-02 2023-12-14 細胞選択方法及び細胞代謝改変方法
JP2025196708A JP2026048662A (ja) 2018-02-02 2025-11-17 細胞選択方法及び細胞代謝改変方法

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US201862625773P 2018-02-02 2018-02-02
US62/625,773 2018-02-02
PCT/US2019/016403 WO2019152876A2 (en) 2018-02-02 2019-02-01 Methods of cell selection and modifying cell metabolism

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JP2022112973A Active JP7404453B2 (ja) 2018-02-02 2022-07-14 細胞選択方法及び細胞代謝改変方法
JP2023210793A Pending JP2024037889A (ja) 2018-02-02 2023-12-14 細胞選択方法及び細胞代謝改変方法
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JP2023210793A Pending JP2024037889A (ja) 2018-02-02 2023-12-14 細胞選択方法及び細胞代謝改変方法
JP2025196708A Pending JP2026048662A (ja) 2018-02-02 2025-11-17 細胞選択方法及び細胞代謝改変方法

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US (2) US12077786B2 (https=)
EP (2) EP3741853B1 (https=)
JP (4) JP7108036B2 (https=)
CN (2) CN116218782A (https=)
ES (2) ES2871818T3 (https=)
GB (1) GB2577236A (https=)
WO (1) WO2019152876A2 (https=)

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EP3741853B1 (en) 2018-02-02 2023-11-22 Lonza Ltd. Methods of cell selection and modifying cell metabolism
US20220403398A1 (en) 2019-11-14 2022-12-22 Lonza Ltd Methods of cell selection
CN114681386A (zh) * 2022-03-16 2022-07-01 和携科技有限公司 一种动物来源外泌体组合物及其在制备皮肤抗衰老和抗过敏制剂中的应用
CN115029307A (zh) * 2022-07-28 2022-09-09 吉林大学 一种延缓MSCs衰老的方法
CN120283058A (zh) * 2022-09-30 2025-07-08 西格马-奥尔德里奇有限责任公司 经由甘氨酸-甲酸盐生物合成途径的代谢选择
EP4594506A1 (en) * 2022-09-30 2025-08-06 Sigma-Aldrich Co., LLC Metabolic selection via the serine biosynthesis pathway
CN116970559B (zh) * 2023-09-21 2023-11-28 派能生物科技（深圳）有限公司 一种制备脂肪间充质干细胞因子的诱导培养基及其应用
WO2026062080A1 (en) * 2024-09-17 2026-03-26 Ares Trading S.A. Cell having increased secretion capabilities and method of use

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JP7404453B2 (ja) 2023-12-25
GB2577236A (en) 2020-03-18
JP2022160453A (ja) 2022-10-19
CN116218782A (zh) 2023-06-06
WO2019152876A3 (en) 2019-11-07
JP2024037889A (ja) 2024-03-19
US12077786B2 (en) 2024-09-03
EP3645720A2 (en) 2020-05-06
EP3645720B1 (en) 2021-03-10
GB202001194D0 (en) 2020-03-11
ES2972544T3 (es) 2024-06-13
ES2871818T3 (es) 2021-11-02
US20230174971A1 (en) 2023-06-08
EP3741853A1 (en) 2020-11-25
WO2019152876A2 (en) 2019-08-08
JP2021511781A (ja) 2021-05-13
CN111971388A (zh) 2020-11-20
JP2026048662A (ja) 2026-03-17
US20240401003A1 (en) 2024-12-05
CN111971388B (zh) 2023-01-31
EP3741853B1 (en) 2023-11-22

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