JP7094029B2 - ミセル触媒作用によってdnaコンジュゲートを合成する方法 - Google Patents
ミセル触媒作用によってdnaコンジュゲートを合成する方法 Download PDFInfo
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- JP7094029B2 JP7094029B2 JP2019565061A JP2019565061A JP7094029B2 JP 7094029 B2 JP7094029 B2 JP 7094029B2 JP 2019565061 A JP2019565061 A JP 2019565061A JP 2019565061 A JP2019565061 A JP 2019565061A JP 7094029 B2 JP7094029 B2 JP 7094029B2
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- Prior art keywords
- small organic
- dna
- molecule
- reaction
- organic molecule
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17156047.7 | 2017-02-14 | ||
| EP17156047.7A EP3360962A1 (en) | 2017-02-14 | 2017-02-14 | Synthesis of dna-encoded libraries by micellar catalysis |
| PCT/EP2018/053650 WO2018149863A1 (en) | 2017-02-14 | 2018-02-14 | Method for the synthesis of dna conjugates by micellar catalysis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020507346A JP2020507346A (ja) | 2020-03-12 |
| JP2020507346A5 JP2020507346A5 (enExample) | 2021-02-12 |
| JP7094029B2 true JP7094029B2 (ja) | 2022-07-01 |
Family
ID=58056978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019565061A Expired - Fee Related JP7094029B2 (ja) | 2017-02-14 | 2018-02-14 | ミセル触媒作用によってdnaコンジュゲートを合成する方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11407993B2 (enExample) |
| EP (2) | EP3360962A1 (enExample) |
| JP (1) | JP7094029B2 (enExample) |
| CN (1) | CN110300804B (enExample) |
| WO (1) | WO2018149863A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7691417B2 (ja) * | 2019-10-03 | 2025-06-11 | アトムワイズ,インコーポレイテッド | インシリコで化合物をスクリーニングするためのシステムおよび方法 |
| CN112831843A (zh) * | 2019-11-22 | 2021-05-25 | 成都先导药物开发股份有限公司 | 一种一锅法On-DNA铃木反应方法 |
| GB202103343D0 (en) | 2021-03-11 | 2021-04-28 | Univ Newcastle | Micellar catalysis |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002345460A (ja) | 2001-03-23 | 2002-12-03 | Fuji Photo Film Co Ltd | 修飾触媒及びそれを用いた反応器並びに防汚樹脂組成物 |
| JP2008530246A (ja) | 2005-02-18 | 2008-08-07 | サーフェイス ロジックス,インコーポレイティド | 機能性残基又は官能基を含む薬物動態学的に改善された化合物、及び上述の化合物を含む医薬組成物の製造方法 |
| JP2015533296A (ja) | 2012-11-05 | 2015-11-24 | ルビコン ゲノミクス インコーポレイテッド | バーコード化する核酸 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5529525A (en) * | 1978-08-21 | 1980-03-01 | Hidetoshi Tsuchida | Metal complex of hydrophilic and hydrophobic block copolymer |
| JPS55144048A (en) * | 1979-04-27 | 1980-11-10 | Hidetoshi Tsuchida | Coordination high polymeric metal complex composition for adsorption-desorption of oxygen |
| GB0307428D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
| WO2007048423A1 (en) * | 2005-10-26 | 2007-05-03 | Stichting Dutch Polymer Institute | Unimolecular micelles containing metal nanoparticles and their use as catalyst for synthesis of carbon-carbon-bonds |
| EP1972349A1 (en) * | 2007-03-21 | 2008-09-24 | Biocompatibles UK Limited | GLP-1 fusion peptides conjugated to polymer(s), their production and use |
| WO2010053597A2 (en) * | 2008-11-06 | 2010-05-14 | University Of Washington/////////////////////-+ | Micelles of hydrophilically shielded membrane-destabilizing copolymers |
| WO2010091144A1 (en) * | 2009-02-04 | 2010-08-12 | Wake Forest University Health Sciences | Compositions, methods, and kits for identifying candidate molecules from encoded chemical libraries |
| WO2010118471A1 (en) * | 2009-04-17 | 2010-10-21 | The University Of Queensland | Reactor and method for performing a chemical reaction |
| DK2748357T3 (en) * | 2011-09-07 | 2018-07-16 | X Chem Inc | Methods for labeling DNA-encoded libraries |
| EP3184674A1 (en) | 2015-12-23 | 2017-06-28 | Technische Universität Dortmund | Dna-encoded chemical library, use thereof and method to synthesize the library |
-
2017
- 2017-02-14 EP EP17156047.7A patent/EP3360962A1/en not_active Withdrawn
-
2018
- 2018-02-14 US US16/485,458 patent/US11407993B2/en active Active
- 2018-02-14 JP JP2019565061A patent/JP7094029B2/ja not_active Expired - Fee Related
- 2018-02-14 EP EP18703801.3A patent/EP3583211B1/en active Active
- 2018-02-14 WO PCT/EP2018/053650 patent/WO2018149863A1/en not_active Ceased
- 2018-02-14 CN CN201880012015.6A patent/CN110300804B/zh not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002345460A (ja) | 2001-03-23 | 2002-12-03 | Fuji Photo Film Co Ltd | 修飾触媒及びそれを用いた反応器並びに防汚樹脂組成物 |
| JP2008530246A (ja) | 2005-02-18 | 2008-08-07 | サーフェイス ロジックス,インコーポレイティド | 機能性残基又は官能基を含む薬物動態学的に改善された化合物、及び上述の化合物を含む医薬組成物の製造方法 |
| JP2015533296A (ja) | 2012-11-05 | 2015-11-24 | ルビコン ゲノミクス インコーポレイテッド | バーコード化する核酸 |
Non-Patent Citations (3)
| Title |
|---|
| Bioconjugate Chem.,2015年,Vol. 26,pp. 1687-1691 |
| Macromolecules,2012年,Vol. 45,pp. 2377-2384 |
| Polymer Preprints,2007年,Vol. 48, No. 2,pp. 539-540 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3583211B1 (en) | 2024-04-10 |
| CN110300804A (zh) | 2019-10-01 |
| EP3583211A1 (en) | 2019-12-25 |
| US20220002712A1 (en) | 2022-01-06 |
| US11407993B2 (en) | 2022-08-09 |
| CN110300804B (zh) | 2024-02-02 |
| WO2018149863A1 (en) | 2018-08-23 |
| JP2020507346A (ja) | 2020-03-12 |
| EP3360962A1 (en) | 2018-08-15 |
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