JP7090551B2 - 眼状態の治療方法 - Google Patents

眼状態の治療方法 Download PDF

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Publication number
JP7090551B2
JP7090551B2 JP2018553080A JP2018553080A JP7090551B2 JP 7090551 B2 JP7090551 B2 JP 7090551B2 JP 2018553080 A JP2018553080 A JP 2018553080A JP 2018553080 A JP2018553080 A JP 2018553080A JP 7090551 B2 JP7090551 B2 JP 7090551B2
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compound
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administered
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JP2019513759A (ja
JP2019513759A5 (cg-RX-API-DMAC10.html
Inventor
ダグラス マイケル ジュニア アッカーマン
ジェームズ ルーディン
ケネス ジェイ． マンデル
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オイスター ポイント ファーマ インコーポレイテッド
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Priority to JP2022095460A priority Critical patent/JP2022120125A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP2018553080A 2016-04-07 2017-04-06 眼状態の治療方法 Active JP7090551B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022095460A JP2022120125A (ja) 2016-04-07 2022-06-14 眼状態の治療方法
JP2024086805A JP2024103594A (ja) 2016-04-07 2024-05-29 眼状態の治療方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662319648P 2016-04-07 2016-04-07
US62/319,648 2016-04-07
PCT/US2017/026385 WO2017177024A1 (en) 2016-04-07 2017-04-06 Methods of treating ocular conditions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022095460A Division JP2022120125A (ja) 2016-04-07 2022-06-14 眼状態の治療方法

Publications (3)

Publication Number Publication Date
JP2019513759A JP2019513759A (ja) 2019-05-30
JP2019513759A5 JP2019513759A5 (cg-RX-API-DMAC10.html) 2020-05-14
JP7090551B2 true JP7090551B2 (ja) 2022-06-24

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Family Applications (3)

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JP2018553080A Active JP7090551B2 (ja) 2016-04-07 2017-04-06 眼状態の治療方法
JP2022095460A Pending JP2022120125A (ja) 2016-04-07 2022-06-14 眼状態の治療方法
JP2024086805A Pending JP2024103594A (ja) 2016-04-07 2024-05-29 眼状態の治療方法

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JP2022095460A Pending JP2022120125A (ja) 2016-04-07 2022-06-14 眼状態の治療方法
JP2024086805A Pending JP2024103594A (ja) 2016-04-07 2024-05-29 眼状態の治療方法

Country Status (19)

Country Link
US (3) US10709707B2 (cg-RX-API-DMAC10.html)
EP (2) EP3970724A1 (cg-RX-API-DMAC10.html)
JP (3) JP7090551B2 (cg-RX-API-DMAC10.html)
KR (2) KR102512777B1 (cg-RX-API-DMAC10.html)
CN (3) CN114533737B (cg-RX-API-DMAC10.html)
AU (1) AU2017248276B2 (cg-RX-API-DMAC10.html)
DK (1) DK3439661T3 (cg-RX-API-DMAC10.html)
EA (1) EA201892265A1 (cg-RX-API-DMAC10.html)
ES (1) ES2893126T3 (cg-RX-API-DMAC10.html)
IL (3) IL299204A (cg-RX-API-DMAC10.html)
MX (2) MX385698B (cg-RX-API-DMAC10.html)
MY (1) MY199237A (cg-RX-API-DMAC10.html)
NZ (1) NZ746468A (cg-RX-API-DMAC10.html)
PH (1) PH12018502154A1 (cg-RX-API-DMAC10.html)
PT (1) PT3439661T (cg-RX-API-DMAC10.html)
SG (1) SG11201808650QA (cg-RX-API-DMAC10.html)
TW (2) TWI876258B (cg-RX-API-DMAC10.html)
WO (1) WO2017177024A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201807438B (cg-RX-API-DMAC10.html)

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US9145396B2 (en) 2008-12-01 2015-09-29 Targacept, Inc. Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3ylvinyl)pyrimidine
CN107106542B (zh) 2014-10-20 2020-05-08 奥伊斯特普安生物制药公司 治疗眼部病状的方法
NZ746468A (en) * 2016-04-07 2023-06-30 Oyster Point Pharma Inc Methods of treating ocular conditions
WO2020014217A1 (en) 2018-07-10 2020-01-16 Oyster Point Pharma, Inc. Methods of treating ocular conditions
EP3820443A1 (en) 2018-07-10 2021-05-19 Oyster Point Pharma, Inc. Combinations of positive allosteric modulators and nicotinic acetylcholine receptor agonists for treating ocular conditions
EP4142734B1 (en) * 2020-04-28 2025-08-20 Oyster Point Pharma, Inc. Local administration of nicotinic acetylcholine receptor agonists for the inhibition of coronavirus infections
JP2024517459A (ja) * 2021-05-07 2024-04-22 オイスター ポイント ファーマ インコーポレイテッド ベクター及びニコチン作動薬の併用療法
WO2026080563A1 (en) 2024-10-09 2026-04-16 Oyster Point Pharma, Inc. Simpinicline oral formations and use thereof

Citations (3)

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JP2003531168A (ja) 2000-04-21 2003-10-21 インスパイアー ファーマシューティカルズ，インコーポレイティド ニコチン・アセチルコリン受容体アゴニストによるドライ・アイ疾患の治療方法
JP2012510471A (ja) 2008-12-01 2012-05-10 ターガセプト，インコーポレイテッド （ｒ）−５−（（ｅ）−２−（ピロリジン−３−イルビニル）ピリミジンの合成および新規の塩形態
JP2017531044A (ja) 2014-10-20 2017-10-19 オイスター ポイント ファーマ インコーポレイテッド 眼の病状の治療方法

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AU2003269413A1 (en) 2002-11-01 2004-05-25 Pharmacia & Upjohn Company Llc Nicotinic acetylcholine agonists in the treatment of glaucoma and retinal neuropathy
US7098331B2 (en) 2003-03-05 2006-08-29 Targacept, Inc. Arylvinylazacycloalkane compounds and methods of preparation and use thereof
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TWI405763B (zh) 2006-11-02 2013-08-21 Targacept Inc 菸鹼乙醯膽鹼受體亞型選擇性之二氮雜雙環烷類醯胺
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JP2003531168A (ja) 2000-04-21 2003-10-21 インスパイアー ファーマシューティカルズ，インコーポレイティド ニコチン・アセチルコリン受容体アゴニストによるドライ・アイ疾患の治療方法
JP2012510471A (ja) 2008-12-01 2012-05-10 ターガセプト，インコーポレイテッド （ｒ）−５−（（ｅ）−２−（ピロリジン−３−イルビニル）ピリミジンの合成および新規の塩形態
JP2017531044A (ja) 2014-10-20 2017-10-19 オイスター ポイント ファーマ インコーポレイテッド 眼の病状の治療方法

Also Published As

Publication number Publication date
JP2024103594A (ja) 2024-08-01
KR20190005859A (ko) 2019-01-16
US20190201397A1 (en) 2019-07-04
CN114533737B (zh) 2024-05-31
PH12018502154A1 (en) 2019-07-08
US10709707B2 (en) 2020-07-14
WO2017177024A8 (en) 2018-11-08
DK3439661T3 (da) 2021-10-18
TWI790997B (zh) 2023-02-01
MX2018012230A (es) 2019-03-28
CN109310692A (zh) 2019-02-05
TW201737917A (zh) 2017-11-01
ES2893126T3 (es) 2022-02-08
ZA201807438B (en) 2024-09-25
KR102512777B1 (ko) 2023-03-23
EP3439661A1 (en) 2019-02-13
IL290069B1 (en) 2023-01-01
AU2017248276A1 (en) 2018-11-22
US20250000861A1 (en) 2025-01-02
JP2019513759A (ja) 2019-05-30
WO2017177024A1 (en) 2017-10-12
EP3970724A1 (en) 2022-03-23
ES2893126T8 (es) 2022-05-23
MX385698B (es) 2025-03-18
TWI876258B (zh) 2025-03-11
CN114432313A (zh) 2022-05-06
EP3439661B1 (en) 2021-08-04
IL299204A (en) 2023-02-01
IL290069A (en) 2022-03-01
EA201892265A1 (ru) 2019-04-30
PT3439661T (pt) 2021-09-30
IL290069B2 (en) 2023-05-01
CN114533737A (zh) 2022-05-27
BR112018070497A2 (pt) 2019-01-29
NZ785093A (en) 2024-07-05
TW202320785A (zh) 2023-06-01
MX2021010399A (es) 2022-01-18
IL262102B (en) 2022-03-01
SG11201808650QA (en) 2018-10-30
MY199237A (en) 2023-10-22
CN109310692B (zh) 2022-01-25
JP2022120125A (ja) 2022-08-17
US20200345734A1 (en) 2020-11-05
IL262102A (en) 2018-11-29
NZ746468A (en) 2023-06-30
AU2017248276B2 (en) 2023-07-13
CA3020170A1 (en) 2017-10-12
KR20230010813A (ko) 2023-01-19
KR102485299B1 (ko) 2023-01-06

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