JP7079551B2 - ヒドロキシチロソールおよびボスウェリン酸を有する組成物 - Google Patents

ヒドロキシチロソールおよびボスウェリン酸を有する組成物 Download PDF

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JP7079551B2
JP7079551B2 JP2019516976A JP2019516976A JP7079551B2 JP 7079551 B2 JP7079551 B2 JP 7079551B2 JP 2019516976 A JP2019516976 A JP 2019516976A JP 2019516976 A JP2019516976 A JP 2019516976A JP 7079551 B2 JP7079551 B2 JP 7079551B2
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hydroxytyrosol
composition
keto
acetyl
boswellic acid
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Japanese (ja)
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JP2019529482A5 (https=
JP2019529482A (ja
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ヘンダーソン，トッド
グリフィン，デイヴィッド
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ニュートラマックス ラボラトリーズ，インコーポレイテッド
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Priority to JP2022082301A priority Critical patent/JP7341596B2/ja
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Priority to JP2023137408A priority patent/JP7562225B2/ja
Priority to JP2024163552A priority patent/JP2024166415A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
JP2019516976A 2016-10-04 2017-04-21 ヒドロキシチロソールおよびボスウェリン酸を有する組成物 Active JP7079551B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2022082301A JP7341596B2 (ja) 2016-10-04 2022-05-19 炎症メディエーターのレベルを低減するための組成物及び方法
JP2023137408A JP7562225B2 (ja) 2016-10-04 2023-08-25 炎症メディエーターのレベルを低減するための組成物及び方法
JP2024163552A JP2024166415A (ja) 2016-10-04 2024-09-20 炎症メディエーターのレベルを低減するための組成物及び方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662403807P 2016-10-04 2016-10-04
US62/403,807 2016-10-04
PCT/US2017/028857 WO2018067200A1 (en) 2016-10-04 2017-04-21 Compositions comprising hydroxytyrosol and boswellic acid

Related Child Applications (1)

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JP2022082301A Division JP7341596B2 (ja) 2016-10-04 2022-05-19 炎症メディエーターのレベルを低減するための組成物及び方法

Publications (3)

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JP2019529482A JP2019529482A (ja) 2019-10-17
JP2019529482A5 JP2019529482A5 (https=) 2020-05-28
JP7079551B2 true JP7079551B2 (ja) 2022-06-02

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ID=58664857

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2019516976A Active JP7079551B2 (ja) 2016-10-04 2017-04-21 ヒドロキシチロソールおよびボスウェリン酸を有する組成物
JP2022082301A Active JP7341596B2 (ja) 2016-10-04 2022-05-19 炎症メディエーターのレベルを低減するための組成物及び方法
JP2023137408A Active JP7562225B2 (ja) 2016-10-04 2023-08-25 炎症メディエーターのレベルを低減するための組成物及び方法
JP2024163552A Pending JP2024166415A (ja) 2016-10-04 2024-09-20 炎症メディエーターのレベルを低減するための組成物及び方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2022082301A Active JP7341596B2 (ja) 2016-10-04 2022-05-19 炎症メディエーターのレベルを低減するための組成物及び方法
JP2023137408A Active JP7562225B2 (ja) 2016-10-04 2023-08-25 炎症メディエーターのレベルを低減するための組成物及び方法
JP2024163552A Pending JP2024166415A (ja) 2016-10-04 2024-09-20 炎症メディエーターのレベルを低減するための組成物及び方法

Country Status (9)

Country Link
US (3) US11241444B2 (https=)
EP (2) EP4623994A3 (https=)
JP (4) JP7079551B2 (https=)
CN (2) CN109789110A (https=)
AU (3) AU2017340126B2 (https=)
CA (1) CA3039233A1 (https=)
ES (1) ES3040765T3 (https=)
PL (1) PL3522874T3 (https=)
WO (1) WO2018067200A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7079551B2 (ja) 2016-10-04 2022-06-02 ニュートラマックス ラボラトリーズ，インコーポレイテッド ヒドロキシチロソールおよびボスウェリン酸を有する組成物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102451428A (zh) 2010-10-14 2012-05-16 中国中医科学院广安门医院 可用于治疗类风湿关节炎的中药组合物

Family Cites Families (15)

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Publication number Priority date Publication date Assignee Title
US6358542B2 (en) 1999-12-20 2002-03-19 Usana, Inc. Antioxidant compositions extracted from olives and olive by-products
US7713569B2 (en) 2000-09-01 2010-05-11 Creagri, Inc. Hydroxytyrosol-rich composition from olive vegetation water and method of use thereof
JP3820218B2 (ja) 2000-09-01 2006-09-13 クレアグリ， インコーポレイテッド 植物水からヒドロキシチロソール富化組成物を得る方法
CA2474798C (en) 2002-02-13 2012-12-04 Creagri, Inc. Method and composition for treatment of inflammation and aids-associated neurological disorders
US20030199581A1 (en) 2002-03-13 2003-10-23 Seligson Allen L. Boswellin compositions enhanced with 3-beta-acetyl-11-keto-beta-boswellic acid ("AKBA") industrial manufacture and uses
EP1582512A1 (en) 2004-03-31 2005-10-05 Cognis IP Management GmbH Process for obtaining hydroxytyrosol from olive leaves extracts
US7625947B2 (en) 2004-06-18 2009-12-01 Laila Nutraceuticals Analogs of 3-O-acetyl-11-keto-β-boswellic acid
WO2006020588A1 (en) * 2004-08-09 2006-02-23 Creagri, Inc. Olive compositions and methods for treating inflammatory conditions
EP2040696B1 (en) * 2006-07-14 2017-01-25 DSM IP Assets B.V. Compositions and use thereof for the treatment, co-treatment or prevention of inflammatory disorders
WO2008006582A1 (en) 2006-07-14 2008-01-17 Dsm Ip Assets B.V. Compositions comprising magnolol or honokiol and other active agents for the treatment of inflammatory diseases
JP2008120716A (ja) 2006-11-10 2008-05-29 Eisai Food Chemical Kk 抗炎症剤
KR101682512B1 (ko) * 2008-09-15 2016-12-05 라일라 뉴트라슈티칼스 보스웰리아 세라타 추출물을 포함하는 상승적인 항-염증 조성물
WO2014085613A1 (en) * 2012-11-30 2014-06-05 Mccord Darlene E Hydroxytyrosol and oleuropein compositions for induction of dna damage, cell death and lsd1 inhibition
US10342802B2 (en) 2016-10-04 2019-07-09 Nutramax Laboratories, Inc. Compositions comprising hydroxytyrosol and boswellic acid
JP7079551B2 (ja) 2016-10-04 2022-06-02 ニュートラマックス ラボラトリーズ，インコーポレイテッド ヒドロキシチロソールおよびボスウェリン酸を有する組成物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102451428A (zh) 2010-10-14 2012-05-16 中国中医科学院广安门医院 可用于治疗类风湿关节炎的中药组合物

Non-Patent Citations (4)

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Title
Cancer Res.，2009年，Vol.69,No.14，pp.5893-5900
Current Cancer Drug Targets，Vol.13，2013年，pp.625-639
Journal of Nutritional Biochemistry，Vol.26，2015年，pp.360-368
Molecules，2013年，Vol.18，pp.5265-5287

Also Published As

Publication number Publication date
CA3039233A1 (en) 2018-04-12
EP3522874B1 (en) 2025-07-02
JP2024166415A (ja) 2024-11-28
JP2023159387A (ja) 2023-10-31
JP7562225B2 (ja) 2024-10-07
JP7341596B2 (ja) 2023-09-11
AU2023203427B2 (en) 2025-02-06
ES3040765T3 (en) 2025-11-04
US20220110946A1 (en) 2022-04-14
AU2017340126A1 (en) 2019-04-11
WO2018067200A1 (en) 2018-04-12
US11241444B2 (en) 2022-02-08
CN109789110A (zh) 2019-05-21
US11980624B2 (en) 2024-05-14
JP2022110125A (ja) 2022-07-28
AU2017340126B2 (en) 2023-03-02
JP2019529482A (ja) 2019-10-17
US20200222424A1 (en) 2020-07-16
CN120241745A (zh) 2025-07-04
AU2023203427A1 (en) 2023-06-29
EP4623994A3 (en) 2025-11-19
AU2025202875A1 (en) 2025-05-15
US20240285648A1 (en) 2024-08-29
EP3522874A1 (en) 2019-08-14
PL3522874T3 (pl) 2025-10-06
EP4623994A2 (en) 2025-10-01

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