JP7078620B2 - アレルギーの治療のための核酸 - Google Patents
アレルギーの治療のための核酸 Download PDFInfo
- Publication number
- JP7078620B2 JP7078620B2 JP2019524956A JP2019524956A JP7078620B2 JP 7078620 B2 JP7078620 B2 JP 7078620B2 JP 2019524956 A JP2019524956 A JP 2019524956A JP 2019524956 A JP2019524956 A JP 2019524956A JP 7078620 B2 JP7078620 B2 JP 7078620B2
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nucleic acid
- allergen
- cell
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/06—Fusion polypeptide containing a localisation/targetting motif containing a lysosomal/endosomal localisation signal
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Botany (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022082014A JP2022119861A (ja) | 2016-11-16 | 2022-05-19 | アレルギーの治療のための核酸 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662423111P | 2016-11-16 | 2016-11-16 | |
| US62/423,111 | 2016-11-16 | ||
| US201762536088P | 2017-07-24 | 2017-07-24 | |
| US62/536,088 | 2017-07-24 | ||
| PCT/US2017/061847 WO2018093932A2 (en) | 2016-11-16 | 2017-11-15 | Nucleic acids for treatment of allergies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022082014A Division JP2022119861A (ja) | 2016-11-16 | 2022-05-19 | アレルギーの治療のための核酸 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019537447A JP2019537447A (ja) | 2019-12-26 |
| JP7078620B2 true JP7078620B2 (ja) | 2022-05-31 |
Family
ID=60582661
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019524956A Active JP7078620B2 (ja) | 2016-11-16 | 2017-11-15 | アレルギーの治療のための核酸 |
| JP2022082014A Pending JP2022119861A (ja) | 2016-11-16 | 2022-05-19 | アレルギーの治療のための核酸 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022082014A Pending JP2022119861A (ja) | 2016-11-16 | 2022-05-19 | アレルギーの治療のための核酸 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11826423B2 (https=) |
| EP (1) | EP3541420A2 (https=) |
| JP (2) | JP7078620B2 (https=) |
| CN (1) | CN110418650A (https=) |
| CA (1) | CA3044074A1 (https=) |
| WO (1) | WO2018093932A2 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3808361A1 (en) * | 2012-06-15 | 2021-04-21 | Immunomic Therapeutics, Inc. | Nucleic acids for treatment of allergies |
| US10149904B2 (en) | 2015-02-20 | 2018-12-11 | The Board Of Trusteees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| US10166286B2 (en) | 2015-02-20 | 2019-01-01 | The Board Of Trustees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| US11452774B2 (en) | 2015-02-20 | 2022-09-27 | The Board Of Trustees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| NZ760884A (en) | 2017-07-18 | 2023-05-26 | Nestle Sa | Methods for making mixed allergen compositions |
| US20210163957A1 (en) * | 2018-05-11 | 2021-06-03 | Astellas Pharma Inc. | Nucleic acid for treating mite allergy |
| CA3099505A1 (en) * | 2018-05-11 | 2019-11-14 | Astellas Pharma Inc. | Nucleic acid for treating crustacean allergy |
| US12398195B2 (en) * | 2018-05-15 | 2025-08-26 | Immunomic Therapeutics, Inc. | Lamp constructs comprising allergens |
| WO2019242662A1 (zh) * | 2018-06-22 | 2019-12-26 | 江苏众红生物工程创药研究院有限公司 | 重组尘螨变应原蛋白药物合剂及其应用 |
| CN113507844A (zh) | 2019-01-23 | 2021-10-15 | 前品牌股份有限公司 | 制备混合型过敏原组合物的方法 |
| CN111138514B (zh) * | 2020-01-08 | 2023-09-22 | 海南大学 | 一种腰果多肽及其提取方法和应用 |
| CN117003848A (zh) * | 2022-11-10 | 2023-11-07 | 浙江鼎持生物制品有限公司 | 猫主要过敏原蛋白表达、纯化和组合应用 |
| WO2024153710A2 (en) * | 2023-01-17 | 2024-07-25 | Société des Produits Nestlé S.A. | Mixed nut allergen formulations and methods of making and using the same |
| WO2025139524A1 (zh) * | 2023-12-28 | 2025-07-03 | 江苏众红生物工程创药研究院有限公司 | 猫重组变应原及其药用组合物、制备方法和应用 |
| WO2025247235A1 (en) * | 2024-05-29 | 2025-12-04 | Therorna Shanghai Co., Ltd. | Methods of inducing tumor specific t cells with a circular rna cancer vaccine |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015200357A2 (en) | 2014-06-23 | 2015-12-30 | Immunomic Therapeutics, Inc. | Nucleic acids for treatment of peanut allergies |
Family Cites Families (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4237115A (en) | 1977-11-23 | 1980-12-02 | Bactex, Inc. | Method of immunization against enterotoxogenic infection by Escherichia coli |
| US4397844A (en) | 1978-02-24 | 1983-08-09 | Ciba-Geigy Corporation | Antigen derivatives and processes for their preparation |
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| GB2026340B (en) | 1978-07-03 | 1982-12-22 | Ash P | Stabilising microvesicles |
| US4681762A (en) | 1979-05-23 | 1987-07-21 | Research Corporation | Genetically attenuated bacterial vaccines with multiple mutations of the same phenotype |
| US4603112A (en) | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
| US4769330A (en) | 1981-12-24 | 1988-09-06 | Health Research, Incorporated | Modified vaccinia virus and methods for making and using the same |
| US4593002A (en) | 1982-01-11 | 1986-06-03 | Salk Institute Biotechnology/Industrial Associates, Inc. | Viruses with recombinant surface proteins |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US4592002A (en) | 1983-12-13 | 1986-05-27 | Honeywell Inc. | Method of digital temperature compensation and a digital data handling system utilizing the same |
| ZA858044B (en) | 1984-11-01 | 1987-05-27 | American Home Prod | Oral vaccines |
| FR2583429B1 (fr) | 1985-06-18 | 1989-11-03 | Transgene Sa | Vecteur d'expression de l'interferon u dans les cellules de mammifere, procede pour sa mise en oeuvre et produit obtenu et composition pharmaceutique contenant l'interferon u |
| US4737323A (en) | 1986-02-13 | 1988-04-12 | Liposome Technology, Inc. | Liposome extrusion method |
| DE3642912A1 (de) | 1986-12-16 | 1988-06-30 | Leybold Ag | Messeinrichtung fuer paramagnetische messgeraete mit einer messkammer |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5744166A (en) | 1989-02-25 | 1998-04-28 | Danbiosyst Uk Limited | Drug delivery compositions |
| US5100587A (en) | 1989-11-13 | 1992-03-31 | The United States Of America As Represented By The Department Of Energy | Solid-state radioluminescent zeolite-containing composition and light sources |
| US5179993A (en) | 1991-03-26 | 1993-01-19 | Hughes Aircraft Company | Method of fabricating anisometric metal needles and birefringent suspension thereof in dielectric fluid |
| ATE444360T1 (de) * | 1991-10-16 | 2009-10-15 | Merck Patent Gmbh | T-zell epitopen von den wichtigsten allergene von dermatophagoides (hausmilbe) |
| SE503225C2 (sv) | 1991-10-30 | 1996-04-22 | Leif Lindholm Konsult Ab | Virus-antikroppskomplex för införing av virus i mammalieceller |
| US5747323A (en) | 1992-12-31 | 1998-05-05 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Retroviral vectors comprising a VL30-derived psi region |
| US5633234A (en) | 1993-01-22 | 1997-05-27 | The Johns Hopkins University | Lysosomal targeting of immunogens |
| FR2705686B1 (fr) | 1993-05-28 | 1995-08-18 | Transgene Sa | Nouveaux adénovirus défectifs et lignées de complémentation correspondantes. |
| FR2707091B1 (fr) | 1993-06-30 | 1997-04-04 | Cohen Haguenauer Odile | Vecteur rétroviral pour le transfert et l'expression de gènes dans des cellules eucaryotes. |
| US5928944A (en) | 1994-02-04 | 1999-07-27 | The United States Of America As Represented By The Department Of Health And Human Services | Method of adenoviral-medicated cell transfection |
| FI955320A7 (fi) | 1994-03-07 | 1995-11-24 | Univ Michigan | Bioaktiivisia ja/tai kohdennettuja dendriimikonjugaatteja |
| WO1995028494A1 (en) | 1994-04-15 | 1995-10-26 | Targeted Genetics Corporation | Gene delivery fusion proteins |
| FR2719316B1 (fr) | 1994-04-28 | 1996-05-31 | Idm | Nouveaux complexes d'acide nucléique et de polymère, leur procédé de préparation et leur utilisation pour la transfection de cellules. |
| AU2946295A (en) | 1994-06-27 | 1996-01-19 | Johns Hopkins University, The | Targeted gene delivery system |
| FR2722506B1 (fr) | 1994-07-13 | 1996-08-14 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucleiques, preparation et utilisations |
| FR2727689A1 (fr) | 1994-12-01 | 1996-06-07 | Transgene Sa | Nouveau procede de preparation d'un vecteur viral |
| US5837520A (en) | 1995-03-07 | 1998-11-17 | Canji, Inc. | Method of purification of viral vectors |
| FR2737222B1 (fr) | 1995-07-24 | 1997-10-17 | Transgene Sa | Nouveaux vecteurs viraux et lignee pour la therapie genique |
| WO1997035996A1 (en) | 1996-03-25 | 1997-10-02 | Transgene S.A. | Packaging cell line based on human 293 cells |
| EP0944717A1 (fr) | 1996-07-01 | 1999-09-29 | Aventis Pharma S.A. | Procede de production d'adenovirus recombinants |
| EP0920339A2 (en) | 1996-07-09 | 1999-06-09 | The Johns Hopkins University | Gene delivery system |
| ATE477320T1 (de) | 1996-12-13 | 2010-08-15 | Schering Corp | Methoden zur virus-reinigung |
| FR2759382A1 (fr) | 1997-02-10 | 1998-08-14 | Transgene Sa | Nouveaux composes et compositions les contenant utilisables pour le transfert d'au moins une substance therapeutiquement active, notamment un polynucleotide, dans une cellule cible et utilisation en therapie genique |
| FR2760193B1 (fr) | 1997-02-28 | 1999-05-28 | Transgene Sa | Lipides et complexes de lipides cationiques et de substances actives, notamment pour la transfection de cellules |
| FR2763958A1 (fr) | 1997-05-29 | 1998-12-04 | Transgene Sa | Produit de combinaison associant un acide nucleique a une substance desorganisant la matrice extracellulaire pour la therapie genique |
| AU749032B2 (en) | 1997-06-13 | 2002-06-20 | Johns Hopkins University, The | Therapeutic nanospheres |
| CA2242035C (en) | 1997-07-01 | 2004-11-23 | Transgene S.A. | Compositions useful for transferring therapeutically active substances into a target cell, and their use in gene therapy |
| ES2210081T3 (es) | 1998-07-07 | 2004-07-01 | Transgene S.A. | Utilizacion de los marcos de lectura de la region e4 para la mejora de la expresion de genes. |
| EP1155120B1 (fr) | 1999-02-22 | 2006-07-05 | Transgene S.A. | Procede d'obtention d'une preparation virale purifiee |
| DK1385538T3 (da) | 2001-04-05 | 2013-04-29 | Univ Johns Hopkins | Kimære vacciner omfattende det lumenale domæne fra LAMP-1 eller LAMP-2 |
| US20060251667A1 (en) | 2002-08-29 | 2006-11-09 | Chua Kaw Y | Recombinant nucleic acid useful for inducing protective immune response against allergens |
| WO2004109291A2 (en) | 2003-06-02 | 2004-12-16 | Mount Sinai School Of Medecine Of New York University | Method for diagnosis and therapy of hazelnut-induced systemic reaction |
| EP2028188A1 (en) | 2007-08-21 | 2009-02-25 | Biomay AG | Hypoallergenic molecules |
| WO2013113326A1 (en) | 2012-01-31 | 2013-08-08 | Curevac Gmbh | Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen |
| EP3808361A1 (en) * | 2012-06-15 | 2021-04-21 | Immunomic Therapeutics, Inc. | Nucleic acids for treatment of allergies |
-
2017
- 2017-11-15 CN CN201780077275.7A patent/CN110418650A/zh active Pending
- 2017-11-15 US US16/461,185 patent/US11826423B2/en active Active
- 2017-11-15 WO PCT/US2017/061847 patent/WO2018093932A2/en not_active Ceased
- 2017-11-15 EP EP17809419.9A patent/EP3541420A2/en active Pending
- 2017-11-15 JP JP2019524956A patent/JP7078620B2/ja active Active
- 2017-11-15 CA CA3044074A patent/CA3044074A1/en active Pending
-
2022
- 2022-05-19 JP JP2022082014A patent/JP2022119861A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015200357A2 (en) | 2014-06-23 | 2015-12-30 | Immunomic Therapeutics, Inc. | Nucleic acids for treatment of peanut allergies |
Non-Patent Citations (2)
| Title |
|---|
| J ALLERGY CLIN IMMUNOL,vol.131, no.5,p.1384-1392 |
| Journal of Immunology Research,2016年04月30日,vol.2016, Article ID 4857869,p.1-15 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20190351050A1 (en) | 2019-11-21 |
| WO2018093932A3 (en) | 2018-06-28 |
| JP2022119861A (ja) | 2022-08-17 |
| CA3044074A1 (en) | 2018-05-24 |
| JP2019537447A (ja) | 2019-12-26 |
| US11826423B2 (en) | 2023-11-28 |
| EP3541420A2 (en) | 2019-09-25 |
| WO2018093932A2 (en) | 2018-05-24 |
| CN110418650A (zh) | 2019-11-05 |
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