JP7074673B2 - エンドソーマルｇタンパク質共役受容体のトリパータイト・モジュレーター - Google Patents

エンドソーマルｇタンパク質共役受容体のトリパータイト・モジュレーター Download PDF

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JP7074673B2
JP7074673B2 JP2018532435A JP2018532435A JP7074673B2 JP 7074673 B2 JP7074673 B2 JP 7074673B2 JP 2018532435 A JP2018532435 A JP 2018532435A JP 2018532435 A JP2018532435 A JP 2018532435A JP 7074673 B2 JP7074673 B2 JP 7074673B2
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group
endosomal
compound
formula
optionally
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JP2019503356A (ja
JP2019503356A5 (enExample
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ダブリュー． バネット、ナイジェル
ジェイ．エイチ． ポーター、クリストファー
コール、デレク
ヒックス、ギャレス
淳也 白井
ハースト、ギャヴィン
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Takeda Pharmaceutical Co Ltd
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Takeda Pharmaceutical Co Ltd
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Publication of JP2019503356A5 publication Critical patent/JP2019503356A5/ja
Priority to JP2022078995A priority Critical patent/JP7458681B2/ja
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Priority to JP2024041282A priority patent/JP2024073581A/ja
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    • A—HUMAN NECESSITIES
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/554—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being a steroid plant sterol, glycyrrhetic acid, enoxolone or bile acid
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
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  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
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  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nutrition Science (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
JP2018532435A 2015-12-22 2016-12-21 エンドソーマルｇタンパク質共役受容体のトリパータイト・モジュレーター Active JP7074673B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022078995A JP7458681B2 (ja) 2015-12-22 2022-05-12 エンドソーマルｇタンパク質共役受容体のトリパータイト・モジュレーター
JP2024041282A JP2024073581A (ja) 2015-12-22 2024-03-15 エンドソーマルｇタンパク質共役受容体のトリパータイト・モジュレーター

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2015905333 2015-12-22
AU2015905333A AU2015905333A0 (en) 2015-12-22 Modulators of Endosomal G Protein-Coupled Receptors
US201662291161P 2016-02-04 2016-02-04
US62/291,161 2016-02-04
PCT/US2016/068075 WO2017112792A1 (en) 2015-12-22 2016-12-21 Tripartite modulators of endosomal g protein-coupled receptors

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JP2022078995A Division JP7458681B2 (ja) 2015-12-22 2022-05-12 エンドソーマルｇタンパク質共役受容体のトリパータイト・モジュレーター

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JP2019503356A JP2019503356A (ja) 2019-02-07
JP2019503356A5 JP2019503356A5 (enExample) 2020-02-06
JP7074673B2 true JP7074673B2 (ja) 2022-05-24

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JP2018532435A Active JP7074673B2 (ja) 2015-12-22 2016-12-21 エンドソーマルｇタンパク質共役受容体のトリパータイト・モジュレーター
JP2022078995A Active JP7458681B2 (ja) 2015-12-22 2022-05-12 エンドソーマルｇタンパク質共役受容体のトリパータイト・モジュレーター
JP2024041282A Pending JP2024073581A (ja) 2015-12-22 2024-03-15 エンドソーマルｇタンパク質共役受容体のトリパータイト・モジュレーター

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JP2022078995A Active JP7458681B2 (ja) 2015-12-22 2022-05-12 エンドソーマルｇタンパク質共役受容体のトリパータイト・モジュレーター
JP2024041282A Pending JP2024073581A (ja) 2015-12-22 2024-03-15 エンドソーマルｇタンパク質共役受容体のトリパータイト・モジュレーター

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US (3) US11324832B2 (enExample)
EP (1) EP3393519A1 (enExample)
JP (3) JP7074673B2 (enExample)
CN (2) CN115531553A (enExample)
AU (3) AU2016377658B2 (enExample)
CA (1) CA3009325A1 (enExample)
EA (1) EA201891472A1 (enExample)
WO (1) WO2017112792A1 (enExample)

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RU2770050C2 (ru) 2015-03-04 2022-04-14 Ванда Фармасьютиклз Инк. Способ лечения с применением традипитанта
EA201891472A1 (ru) * 2015-12-22 2018-12-28 Такеда Фармасьютикал Компани Лимитед Тройные модуляторы эндосомальных рецепторов, сопряженных с g-белком
WO2017197463A1 (en) * 2016-05-20 2017-11-23 Monash University Treatment of pain
DK3710000T3 (da) * 2017-11-17 2025-06-16 Vanda Pharmaceuticals Inc Tradipitant til anvendelse til behandling af gastroparese
IT202200018768A1 (it) * 2022-09-14 2024-03-14 Alberto Chiarugi Trattamento della nausea e vomito da chemioterapia
IT202200018780A1 (it) * 2022-09-14 2024-03-14 Alberto Chiarugi Modulatori degli effetti della chemioterapia

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JP2000247957A (ja) 1999-02-24 2000-09-12 F Hoffmann La Roche Ag ４−フェニル−ピリジン誘導体
JP2002537382A (ja) 1999-02-24 2002-11-05 エフ．ホフマン−ラ ロシュ アーゲー ３−フェニルピリジン誘導体、およびそのｎｋ−１受容体拮抗薬としての用途
JP2004504400A (ja) 2000-07-24 2004-02-12 エフ．ホフマン−ラ　ロシュ　アーゲー ニューロキニン１受容体アンタゴニストとしての４−フェニル−ピリジン誘導体
JP2004506718A (ja) 2000-08-08 2004-03-04 エフ．ホフマン−ラ　ロシュ　アーゲー ４−フェニル−ピリジン誘導体

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EA201891472A1 (ru) * 2015-12-22 2018-12-28 Такеда Фармасьютикал Компани Лимитед Тройные модуляторы эндосомальных рецепторов, сопряженных с g-белком

Patent Citations (4)

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JP2000247957A (ja) 1999-02-24 2000-09-12 F Hoffmann La Roche Ag ４−フェニル−ピリジン誘導体
JP2002537382A (ja) 1999-02-24 2002-11-05 エフ．ホフマン−ラ ロシュ アーゲー ３−フェニルピリジン誘導体、およびそのｎｋ−１受容体拮抗薬としての用途
JP2004504400A (ja) 2000-07-24 2004-02-12 エフ．ホフマン−ラ　ロシュ　アーゲー ニューロキニン１受容体アンタゴニストとしての４−フェニル−ピリジン誘導体
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