JP7063567B2 - Composition containing ellagic acid compound - Google Patents

Description

The present invention relates to a composition, in particular a cosmetic composition comprising at least one ellagic acid compound for keratinous substances such as skin.

Compositions such as cosmetics or dermatological products containing one or more ellagic acid compounds have problems in terms of color change over time. Until now, in order to solve this problem, a method of encapsulating an ellagic acid compound has been proposed (see Japanese Patent Laid-Open No. 2005-2012).

However, encapsulation of ellagic acid and / or a salt thereof is not easy.

JP 2005-2012 UK Published Patent No. 2,206,339 US Pat. No. 5,364,633 US Pat. No. 5411744

Cosmetics & Toiletries, February 1990, Vol. 105, pp. 53-64 "Handbook of Surfactants", M.R.Porter, Blackie & Son Publishing (Glasgow and London), 1991, pp. 116-178

It is an object of the present invention to provide a composition containing one or more ellagic acid compounds whose stability has been enhanced so that the color of the composition does not substantially change over time.

The above purpose is
(a) At least one ellagic acid compound and
(b) At least one phosphate compound and
(c) At least one metal oxide and
(d) A composition containing water.
Achieved by a composition, preferably a cosmetic composition, more preferably a skin cosmetic composition, wherein the amount of (a) ellagic acid compound in the composition is 0.1% by mass or more based on the total mass of the composition. can do.

The amount of the (a) ellagic acid compound in the composition may be 0.1 to 5% by mass, preferably 0.2 to 1% by mass, and more preferably 0.3 to 0.8% by mass with respect to the total mass of the composition.

(b) Phosphoric acid compound
Compound (1) of formula (XIV):

[In the formula, R ₁ , R ₂ and R ₃ may be the same or different, with the group OM (M stands for alkali metal) and the group OR ₄ (R ₄ is linear or branched. , Cyclic or aromatic C ₅ to C ₄₀ Represents an alkyl group), OH group, and oxyethylene group (OCH ₂ CH ₂ ) _n (OCH ₂ CHCH ₃ ) _m OR (R is a hydrogen atom or linear or branched Represents a C ₁ to C ₂₀ alkyl group, where n and m are integers, n is in the range 1 to 50, and m is in the range 0 to 50)],
(2) Glycerophospholipids and
(3) You can choose from the group consisting of their mixtures.

(b) The phosphate compound shall be selected from the group consisting of trioleyl phosphate, tri-C _12-15 palace-10 phosphate, potassium cetyl phosphate, setes-10 phosphate, dipotassium phosphate, and mixtures thereof. Can be done.

(b) Phosphoric acid compounds are phosphoric acid monoesters of alkoxylated fatty alcohols containing 12-20 carbon atoms and 1-50 mol of alkylene oxides selected from ethylene oxide and propylene oxide, 12-22. It can be selected from the group consisting of dialkyl phosphates of non-alkoxylated alcohols containing carbon atoms, as well as mixtures thereof.

(b) Phosphoric acid compounds consist of a combination of ceteth-10 phosphate and disetyl phosphate, a combination of ceteth-20 phosphate and disetyl phosphate, and a combination of oleth-5 phosphate and dioleyl phosphate. You can choose.

(b) The phosphoric acid compound can be selected from glycerophospholipids represented by the general formula (XV):

[During the ceremony,
R ₁ and R ₂ contain 4 to 24 carbon atoms independently of each other, saturated or unsaturated, optionally branched, and optionally with one or more hydroxyl and / or amine functional groups. Represents a substituted, fatty acid,
X represents the substituent of the general formula R ₃ R ₄ R ₅ N ⁺ -CH (R ₆ ) -CH _2- , and R ₃ , R ₄ , R ₅ and R ₆ are independent of each other, hydrogen atom, 1 Represents an alkyl group containing up to 6 carbon atoms and / or a carboxyl functional group].

The amount of the (b) phosphoric acid compound in the composition may be 0.01 to 20% by mass, preferably 0.05 to 10% by mass, and more preferably 0.1 to 5% by mass with respect to the total mass of the composition.

(c) The metal oxide can be selected from titanium oxide, iron oxide, zirconium oxide, zinc oxide, cerium oxide and mixtures thereof.

(c) The metal oxide may be uncoated.

(c) The metal oxide may be present in the underlying coating, preferably in the form of particles.

The amount of the (c) metal oxide in the composition may be 0.1 to 30% by mass, preferably 0.5 to 20% by mass, and more preferably 1 to 10% by mass with respect to the total mass of the composition.

The amount of (d) water in the composition may be 50-90% by mass, preferably 60-85% by mass, more preferably 70-80% by mass, based on the total mass of the composition.

The present invention is also a method for preventing or reducing a color change of a composition containing (a) at least one ellagic acid compound, (c) at least one metal oxide, and (d) water. , (B) also relates to a method comprising the step of adding at least one phosphate compound to the composition.

The present invention also comprises (a) at least one ellagic acid compound, (c) at least one metal oxide, and (d) water to prevent or reduce color changes in the composition. b) Also involved in the use of at least one phosphate compound.

As a result of diligent studies, the present inventors have been able to produce a composition containing one or more ellagic acid compounds whose stability has been enhanced so that the color of the composition does not substantially change over time. I found that there was.

Therefore, the composition according to the present invention is
(a) At least one ellagic acid compound and
(b) At least one phosphate compound and
(c) At least one metal oxide and
(d) Including water
The amount of (a) ellagic acid compound in the composition is 0.1% by mass or more with respect to the total mass of the composition.

The composition according to the invention is stable so that its color does not change substantially, preferably from the point of view of yellow or brown in particular. Therefore, the composition according to the present invention does not give a negative impression to the consumer.

In addition, the fact that the color of the composition does not change indicates that the ellagic acid compound can maintain its original form and does not react with any substance, so that the composition according to the present invention exhibits the activity of the ellagic acid compound. Can be maintained.

Since the ellagic acid compound can act as a whitening agent, the composition according to the present invention can be preferably used for whitening a keratin substance such as skin.

Hereinafter, the composition, method, use and the like according to the present invention will be described in detail.

[Composition]
The composition according to the invention comprises (a) at least one ellagic acid compound, (b) at least one phosphoric acid compound, (c) at least one metal oxide, and (d) water. , The amount of (a) ellagic acid compound in the composition is 0.1% by mass or more with respect to the total mass of the composition.

The composition according to the present invention is preferably a composition for cosmetics or dermatology, more preferably a cosmetic composition, and even more preferably a cosmetic care composition for a keratin substance such as skin. In particular, the composition according to the present invention can be used as a cosmetic or dermatological product for whitening keratin substances such as skin.

The above components (a) to (d) and other features of the composition according to the invention will be described below.

(Ellagic acid compound)
The composition according to the invention comprises (a) at least one ellagic acid compound. Two or more kinds of ellagic acid compounds may be used in combination. Therefore, a single type of ellagic acid compound or a combination of different types of ellagic acid compounds can be used.

(a) Elagic acid compounds include ellagic acid and salts thereof, metal complexes thereof, monoethers or polyethers thereof, monoacylated or polyacylated derivatives thereof, and carbonates or carbamate derivatives thereof derived from hydroxyl groups.

(a) It may be preferable that the ellagic acid compound can form a chelate ring having an ion such as a metal ion or a different ellagic acid compound.

Ellagic acid is represented by the following chemical formula. Ellagic acid can be obtained from, for example, Minasolve (product name: Minacare Elage).

Salts of ellagic acid are particularly metal salts, especially alkali metal or alkaline earth metal salts such as sodium, potassium, magnesium and calcium salts; such as methylglutamine, diethanolamine, triethanolamine, choline or bis (triethylamine) salts. Amine salts; may include salts of amino acids, in particular salts of basic amino acids such as arginine, lysine and ornithine.

The metal complex of ellagic acid may include, in particular, a metal complex having zinc and copper.

Monoethers or polyether derivatives of ellagic acid may include, in particular, an alkoxy derivative having 1 to 4 carbon atoms or a condensed derivative of one or more hydroxyl groups of ellagic acid having a sugar or a chain of sugars. In particular, it is a monoether or a polyether derivative having sugars such as 3-methoxyellagic acid or glucose, arabinose, rhamnose and galactose.

The monoacylated or polyacylated derivative of ellagic acid may include, in particular, a saturated or unsaturated acyl group having 2 to 22 carbon atoms. Preferably, these acyl groups are acetic acid, palmitic acid, oleic acid, linoleic acid, linolenic acid, arachidonic acid, stearic acid, brushzic acid, erucic acid, behenic acid and (all Z) -5,8,11,14. , 17-corresponds to eicosapentaenoic acid.

The ether or acylated derivative can be obtained by a polyphenol etherification or acylation method well known to those skilled in the art. Some can also be obtained by extracting from plants.

(a) The ellagic acid compound can be represented by the following chemical formula:

[During the ceremony,
Each of R ₁ to R ₄ is independently a hydrogen atom, an alkyl group, an alkoxy group, a polyoxyalkylene group, or a sugar represented by the following formula:

Show,
R ₅ indicates a hydrogen atom or an alkoxy group].

The above alkyl groups include C _{1 to 20} alkyl groups, preferably C _{1 to 10} alkyl groups, such as methyl group, ethyl group, propyl group, isopropyl group, butyl group, isobutyl group, tert-butyl group, pentyl group and neopentyl. Examples include a group, a hexyl group, a cyclohexyl group, an octyl group, a nonyl group and a decyl group. The alkyl group may be substituted with a halogen group such as a fluorine atom or a hydroxyl group.

Examples of the above-mentioned alkoxy group include a C _{1 to 20} alkoxy group, preferably a C _{1 to 6} alkoxy group, for example, a methoxy group, an ethoxy group, a propoxy group and a butoxy group. The alkoxy group may be substituted with a halogen group such as a fluorine atom or a hydroxyl group.

The composition according to the present invention does not need to contain any capsule or the like in order to encapsulate the ellagic acid compound.

The amount of the (a) ellagic acid compound in the composition according to the present invention is 0.1% by mass or more with respect to the total mass of the above composition.

The amount of the (a) ellagic acid compound in the composition may be 0.2% by mass or more, preferably 0.3% by mass or more, and more preferably 0.4% by mass or more with respect to the total mass of the composition. It is even more preferable that the amount of the (a) ellagic acid compound in the composition according to the present invention is 0.5% by mass or more with respect to the total mass of the composition.

On the other hand, the amount of the (a) ellagic acid compound in the composition according to the present invention is 5% by mass or less, preferably 1% by mass or less, more preferably 0.8% by mass or less, based on the total mass of the composition. It may be there. It is even more preferable that the amount of the (a) ellagic acid compound in the composition according to the present invention is 0.7% by mass or less with respect to the total mass of the composition.

The amount of the (a) ellagic acid compound in the composition according to the present invention is in the range of 0.1 to 5% by mass, preferably 0.2 to 1% by mass, and more preferably 0.3 to 0.8% by mass with respect to the total mass of the composition. It may be there. It is even more preferable that the amount of the (a) ellagic acid compound in the composition according to the present invention is 0.4% by mass to 0.7% by mass with respect to the total mass of the composition.

(Phosphoric acid compound)
The composition according to the invention comprises (b) at least one phosphoric acid compound. Two or more kinds of phosphoric acid compounds may be used in combination. Therefore, a single type of phosphate compound or a combination of different types of phosphate compounds may be used.

The term "phosphoric acid compound" as used herein means a compound having at least one phosphoric acid group.

The "phosphoric acid compound" may have at least one phosphoric acid group, particularly one phosphoric acid group.

The phosphoric acid compound can be selected from organic phosphates, inorganic phosphates and mixtures thereof.

The inorganic phosphate may be preferably selected from a metal salt of phosphoric acid or an inorganic salt of phosphoric acid such as an ammonium salt.

The inorganic phosphate may be more preferably in the form of a metal salt. The metal salt may be an alkali metal salt. The alkali metal salt can be selected from phosphoric acid mono, di or trisodium, and phosphoric acid alkali metal salts such as phosphoric acid mono, di or tripotassium. Dipotassium phosphate may be even more preferred.

It may also be preferable that the organic phosphate be selected from phosphoric acid esters such as mono, di or tri-organic phosphate.

According to one embodiment, (b) the phosphoric acid compound is
Compound (1) of formula (XIV):

[In the formula, R ₁ , R ₂ and R ₃ may be the same or different.
Group OM (M stands for alkali metal such as Na, Li or K, preferably Na or K),
Group OR ₄ (R ₄ represents a linear, branched, cyclic or aromatic C ₅ to C ₄₀ alkyl group, preferably a C ₁₂ to C ₂₀ alkyl group, more preferably a C ₁₆ or C ₁₈ alkyl group. ),
OH group and oxyethylene group (OCH ₂ CH ₂ ) _n (OCH ₂ CHCH ₃ ) _m OR (R is a hydrogen atom or a linear or branched C ₁ to C ₂₀ alkyl group, for example C ₅ to C ₁₈ And C ₁₂ to C ₁₅ alkyl groups, n and m are integers, n is in the range 1 to 50, or equal to 10, m is in the range 0 to 50, or equal to 0). Selected].
(2) Glycerophospholipids and
(3) You can choose from the group consisting of their mixtures.

In equation (XIV), at least one of R ₁ , R ₂ and R ₃ is the group -OM, and at least one of R ₁ , R ₂ and R ₃ is the group -OR ₄ or-( It may be preferable that OCH ₂ CH ₂ ) _n (OCH ₂ CH (CH ₃ )) _m OR (n and m are as described above).

Further, in the above equation (XIV), at least one of R ₁ , R ₂ and R ₃ is a group-OM, and at least one of R ₁ , R ₂ and R ₃ is a group -OH. , R ₁ , R ₂ and R ₃ are based on -OR ₄ or-(OCH ₂ CH ₂ ) _n (OCH ₂ CH (CH ₃ )) _m OR (n and m are as described above). ) May be preferable.

Also, in the above equation (XIV), one of R ₁ , R ₂ and R ₃ is the group -OM, and one of R ₁ , R ₂ and R ₃ is the group -OH. , R ₁ , R ₂ and R ₃ are based on -OR ₄ or-(OCH ₂ CH ₂ ) _n (OCH ₂ CH (CH ₃ )) _m OR (n and m are as described above). ) May be preferable.

Further, in the above formula (XIV), at least one or two of the groups R ₁ , R ₂ and R ₃ , or all of them contain the group -OR ₄ , and R ₄ is linear or linear or It may preferably represent branched C ₁₀ to C ₃₀ , particularly C ₁₅ to C ₂₀ or even C ₁₆ or C ₁₈ alkyl groups. In this case, R ₁ , R ₂ and R ₃ may be the same or different.

Non-limiting examples of these compounds of formula (XIV) include, for example, trioleyl phosphate such as Nikkol TDP sold by Nikko Chemicals, phosphorus such as Nikkol TDP-10 sold by Nikko Chemicals. A mixture of acid and ethylene glycol ether and a triester of C ₁₂ to C ₁₅ fatty alcohol (about 10 EOs) (INCI name: Palace-10 Phosphate Tri-C _{12 to 15} ), sold by DSM Nutritional Products. Examples thereof include potassium cetyl phosphate such as Amphisol K or Arlatone MAP 160K manufactured by Uniqema, and setes-10 phosphate such as Protaphos CET-10 manufactured by Protameen Chemicals.

(b) The phosphoric acid compound may preferably have the function of a surfactant. Therefore, (b) the phosphoric acid compound may be a phosphoric acid surfactant.

(b) Phosphoric acid compounds are phosphoric acid monoesters of alkoxylated fatty alcohols containing 12-20 carbon atoms and 1-50 mol of alkylene oxides selected from ethylene oxide and propylene oxide, 12-22. It can be selected from the group consisting of dialkyl phosphates of non-alkoxylated alcohols containing carbon atoms, as well as mixtures thereof. The alkyl moiety of the fatty alcohol or the non-alkoxylated alcohol may be a linear or branched saturated or unsaturated alkyl group.

(b) Phosphoric acid compounds consist of a combination of ceteth-10 phosphate and disetyl phosphate, a combination of ceteth-20 phosphate and disetyl phosphate, and a combination of oleth-5 phosphate and dioleyl phosphate. You can choose.

As a product containing a combination of Ceteth-10 phosphoric acid and disetyl phosphate, CRODAFOS CES commercially available by Croda Inc. (USA) can be mentioned. As a product containing a combination of Ceteth-20 phosphoric acid and disetyl phosphate, CRODAFOS CS-20 ACID commercially available by Croda Inc. (US) can be mentioned. CRODAFOS HCE, which is commercially available from Croda Inc. (US), can be mentioned as a product containing a combination of oleth-5 phosphate and dioleyl phosphate.

For the purposes of the present invention, the term "glycerophospholipid" refers to an ester obtained by reacting glycerol with at least one saturated or unsaturated fatty acid and phosphoric acid, which phosphoric acid has an amine functional group. Substituted with compounds selected from alcohols, especially β-aminoalcohols. The β-aminoalcohol can be selected from, for example, choline, ethanolamine and / or serine.

Glycerophospholipids can be defined according to the following general formula (XV):

[During the ceremony,
R ₁ and R ₂ contain 4 to 24 carbon atoms independently of each other, saturated or unsaturated, optionally branched, and optionally with one or more hydroxyl and / or amine functional groups. Represents a substituted, fatty acid,
X represents the substituent of the general formula R ₃ R ₄ R ₅ N ⁺ -CH (R ₆ ) -CH _2- , and R ₃ , R ₄ , R ₅ and R ₆ are independent of each other, hydrogen atom, 1 Represents an alkyl group containing up to 6 carbon atoms and / or a carboxyl functional group]. X can be selected from choline, serine and ethanolamine in particular.

According to one embodiment, R ₁ and R ₂ are independent of each other, advantageously butyric acid, caproic acid, caprylic acid, caproic acid, caproic acid, lauric acid, lauroreic acid, myristoleic acid, myristoleic acid, palmitic acid. , Palmitoleic acid, stearic acid, oleic acid, linoleic acid, linolenic acid, arachidonic acid, isostearic acid, dihydroxystearic acid and ricinoleic acid.

The glycerophospholipid may also be a mixture of compounds of the general formula (XV).

Glycerophospholipids suitable for use in the present invention may include, for example, phosphatidylcholine, phosphatidylethanolamine and / or phosphatidylserine.

According to one embodiment, the glycerophospholipid may contain esters of glycerol, unsaturated fatty acids, phosphoric acid and choline, also known as phosphatidylcholine (PC).

Glycerophospholipids suitable for use in the present invention can be derived from lecithin. Lecithin may predominantly contain phosphatidylcholine as a glycerophospholipid.

Phosphatidylcholine (PC) suitable for use in the compositions according to the invention may be of "natural" or "synthetic" origin.

"Natural" PCs can be obtained by extraction from animal or plant sources such as soybeans, sunflowers or eggs. For example, non-hydrogenated phosphatidylcholine naturally obtained from soybeans generally contains palmitic acid, stearic acid, palmitoleic acid, oleic acid, linoleic acid, linolenic acid, and optionally C _20-22 fatty acids as glycerol esterified fatty acids. do.

For the purposes of the present invention, the term "synthetic phosphatidylcholine" is intended to mean phosphatidylcholine containing at least one fatty acid that is different from that that may be present in natural PC.

The term "synthetic PC" is also intended to mean a natural PC that has been modified, such as partially hydrogenated, that is, that a small portion of the double bonds present in the unsaturated fatty acid are maintained.

Among the sources of some purified phosphatidylcholine suitable for use in the cosmetic compositions according to the invention is the Emulmetik 930 sold by Lucas Meyer.

Glycerophospholipids suitable for use in the present invention can be introduced into the composition in the form of lecithin. This lecithin is generally obtained from vegetable or animal fats by lipid extraction using a non-polar solvent. This lipid fraction usually contains predominantly glycerophospholipids, including phosphatidylcholine or phosphatidylethanolamine.

Lecithin suitable for use in the present invention may be lecithin derived from soybean, sunflower or egg and / or a mixture thereof.

Lecithin is usually supplied in the form dissolved in fatty acids, triglycerides or other solvents, or in the form of powder or cake.

These are usually mixtures of lecithin sold in products with glycerophospholipid content generally in the range of at least about 15% to at least about 95%.

In an exemplary embodiment, lecithin used as a starting material for the preparation of the compositions according to the invention is at least 45% by weight, eg at least 65% by weight, eg at least 75% by weight, based on the total mass of lecithin. It contains, for example, at least 85% by weight, or, for example, at least 95% by weight, glycerophospholipid.

Among the lecithins that may be suitable for use in the cosmetic compositions according to the invention, they are sold by American Lecithin Company under the reference names Nattermann Phospholipid®, Phospholipon 80® and Phosale 75®. Examples include lecithin, as well as Epikuron 145V, Topcithin 300, Emulmetik 930 and Ovothin 200 sold by Lucas Meyer.

The glycerophospholipid may be a non-hydrogenated glycerophospholipid, that is, an ester obtained by reacting glycerol with at least one unsaturated fatty acid and phosphoric acid, and the phosphoric acid is an alcohol having an amine functional group, particularly. Substituted with a compound selected from β-aminoalcohols.

The terms "unsaturated" and "unsaturated" are intended to mean the presence of at least one or even several double or triple bonds between two carbon atoms.

The glycerophospholipid may be phosphatidylcholine or lecithin.

(b) Phosphoric acid compounds are trioleyl phosphate, a mixture of phosphate and ethylene glycol ether and a triester of C ₁₂ to C ₁₅ fatty alcohol (about 10 EOs), potassium cetyl phosphate, and cetes-10 phosphorus. You can choose from acid, dipotassium phosphate, cetyl phosphate and lecithin, and mixtures thereof.

(b) The phosphoric acid compound is a nonionic surfactant such as trioleyl phosphate or a mixture of an ether of phosphoric acid and ethylene glycol and a triester of C ₁₂ to C ₁₅ fatty alcohol (about 10 EOs). It may be there.

The amount of the (b) phosphoric acid compound in the composition according to the present invention may be 0.01% by mass or more, preferably 0.05% by mass or more, and more preferably 0.1% by mass or more with respect to the total mass of the composition. It is even more preferable that the amount of the (b) phosphoric acid compound in the composition according to the present invention is 0.5% by mass or more with respect to the total mass of the composition.

On the other hand, the amount of the (b) phosphoric acid compound in the composition according to the present invention is 20% by mass or less, preferably 10% by mass or less, more preferably 5% by mass or less, based on the total mass of the composition. It may be there. It is even more preferable that the amount of the (b) phosphoric acid compound in the composition according to the present invention is 3% by mass or less with respect to the total mass of the composition.

The amount of the (b) phosphoric acid compound in the composition according to the present invention ranges from 0.01 to 20% by mass, preferably 0.05 to 10% by mass, more preferably 0.1 to 5% by mass, based on the total mass of the composition. May be. It is even more preferable that the amount of the (b) phosphoric acid compound in the composition according to the present invention is 0.5 to 3% by mass with respect to the total mass of the composition.

(Metal oxide)
The composition according to the invention (c) comprises at least one metal oxide. Two or more kinds of (c) metal oxides may be used in combination. Therefore, a single type of metal oxide or a combination of different types of metal oxides may be used.

(c) The metal oxide can be selected from titanium oxide, iron oxide, zirconium oxide, zinc oxide, cerium oxide and mixtures thereof. The titanium oxide is preferably titanium dioxide. Titanium oxide may be crystalline in the rutile and / or anatase form, even if it is amorphous.

(c) The metal oxide is preferably in the form of particles, particularly pigments, more preferably nanopigments. (c) The particle size (eg, volume or mass average particle diameter) of the metal oxide particles may be 1 nm to 100 μm, preferably 5 nm to 50 μm, more preferably 10 nm to 30 μm.

(c) The metal oxide may or may not be coated.

Coated metal oxides are, for example, compounds described in Cosmetics & Toiletries, February 1990, Vol. 105, pp. 53-64, such as amino acids, bead waxes, fatty acids, fatty alcohols, anionic surfactants, lecithin. , Fatty acid sodium salt, potassium salt, zinc salt, iron salt or aluminum salt, metal (titanium or aluminum) alkoxide, polyethylene, silicone, protein (collagen or elastin), alkanolamine, silicon oxide, metal oxide, sodium hexametaphosphate , Alumina or glycerol, may be treated nanopigments that have been surface treated with one or more of chemical, electrical, mesochemical and / or mechanical properties.

Treated nanopigments include titanium oxide treated with silica and alumina, such as Tayca's products "Microtitanium Dioxide MT 500 SA" and "Microtitanium Dioxide MT 100 SA", and Tioxide's product "Tioveil Fin". "Tioveil OPERATIONS MANAGER", "Tioveil MOTG" and "Tioveil IPM",
Titanium oxide treated with alumina and aluminum stearate, such as Tayca's product "Microtitanium Dioxide MT 100 T",
Titanium oxide treated with alumina and aluminum laurate, such as Tayca's product "Microtitanium Dioxide MT 100 S",
Titanium oxide treated with iron oxide and iron stearate, such as Tayca's product "Microtitanium Dioxide MT 100 F",
Titanium oxide treated with silica, alumina and silicone, such as Tayca's products "Microtitanium Dioxide MT 100 SAS", "Microtitanium Dioxide MT 600 SAS" and "Microtitanium Dioxide MT 500 SAS",
Titanium oxide treated with sodium hexametaphosphate, such as Tayca's product "Microtitanium Dioxide MT 150 W",
Titanium oxide treated with octyltrimethoxysilane, such as Degussa's product "T-805",
Titanium oxide treated with alumina and stearic acid, such as Kemira's product "UVT-M 160",
Titanium oxide treated with alumina and glycerol, such as Kemira's product "UVT-M 212", and alumina and silicone treated titanium oxide, such as Kemira's product "UVT-M 262".
It may be coated titanium oxide such as.

The treated zinc oxide may be, for example, one sold by Sunsmart under the name "Z-COTE HP 1".

(c) The metal oxide is preferably uncoated.

The uncoated metal oxide may be untreated titanium oxide, such as that sold by Tayca under the trade name "Microtitanium Dioxide MT 500B" or "Microtitanium Dioxide MT 600B".

Uncoated metal oxides are untreated zinc oxide, such as those sold by Sumitomo under the name "Ultra Fine Zinc Oxide Powder", those sold by Presperse under the name "Finex 25", Ikeda. It may be sold by the company under the name "MZO-25" or by Sunsmart under the name "Z-COTE".

(c) The metal oxide is introduced as is or in the form of a pigment paste, i.e. mixed with a dispersant, into the composition according to the invention, eg, as described in the literature, UK Publication No. 2,206,339. be able to.

(c) The metal oxide can be present in the substrate, preferably in the coating of particles, particularly pigments, more preferably pearl luster pigments. For example, the metal oxide may be present in the coating of a pearl luster pigment such as titanium oxide coated mica and titanium oxide coated glass fine particles. The coating does not have to be further coated and may therefore be exposed to the environment.

Accordingly, as the metal oxide in the present invention, pearl luster pigments such as titanium oxide-coated mica and titanium oxide-coated glass fine particles can be used.

It is preferred to use granular titanium dioxide particles or mica (and) titanium oxide as the (c) metal oxide.

The amount of the (c) metal oxide in the composition according to the present invention may be 0.1% by mass or more, preferably 0.5% by mass or more, and more preferably 1% by mass or more with respect to the total mass of the composition. It is even more preferable that the amount of the (c) metal oxide in the composition according to the present invention is 1.5% by mass or more with respect to the total mass of the composition.

On the other hand, the amount of (c) metal oxide in the composition according to the present invention is 30% by mass or less, preferably 20% by mass or less, more preferably 10% by mass or less, based on the total mass of the composition. It may be there. It is even more preferable that the amount of (c) the metal oxide in the composition according to the present invention is 5% by mass or less with respect to the total mass of the composition.

The amount of (c) metal oxide in the composition according to the present invention is in the range of 0.1 to 30% by mass, preferably 0.5 to 20% by mass, and more preferably 1 to 10% by mass with respect to the total mass of the composition. May be. It is even more preferable that the amount of (c) the metal oxide in the composition according to the present invention is 0.5 to 3% by mass with respect to the total mass of the composition.

(water)
The composition according to the invention comprises (d) water.

The amount of (d) water in the composition according to the present invention may be 50% by mass or more, preferably 60% by mass or more, and more preferably 70% by mass or more with respect to the total mass of the composition. It is even more preferable that the amount of (d) water in the composition according to the present invention is 72% by mass or more with respect to the total mass of the composition.

On the other hand, the amount of (d) water in the composition according to the present invention may be 90% by mass or less, preferably 85% by mass or less, more preferably 80% by mass or less, based on the total mass of the composition. .. It is even more preferable that the amount of (d) water in the composition according to the present invention is 78% by mass or less with respect to the total mass of the composition.

The amount of (d) water in the composition according to the present invention may be 50 to 90% by mass, preferably 60 to 85% by mass, and more preferably 70 to 80% by mass with respect to the total mass of the composition. It is even more preferable that the amount of (d) water in the composition according to the present invention is 72% to 78% by mass with respect to the total mass of the composition.

(Nonionic surfactant)
The composition according to the invention may contain at least one nonionic surfactant. Two or more nonionic surfactants may be used in combination. Therefore, a single type of nonionic surfactant or a combination of different types of nonionic surfactant may be used.

Nonionic surfactants are compounds well known by themselves or by themselves (eg, "Handbook of Surfactants", MRPorter, Blackie & Son Publishing (Glasgow and London), 1991, pp. 116-178). See). Thus, the nonionic surfactant can be selected from, for example, esters of alcohols, α-diols, alkylphenols and fatty acids, these compounds being ethoxylated, propoxylated or glycerolified, eg 8 It may have at least one fatty chain containing up to 30 carbon atoms, the number of ethylene oxide or propylene oxide groups in the range of 2 to 50, and the number of glycerol groups in the range of 1 to 30. .. Maltose derivatives may also be mentioned. Non-limiting but copolymer of ethylene oxide and / or propylene oxide; condensate of ethylene oxide and / or propylene oxide with fatty alcohols; polyethoxylated fatty amides containing, for example, 2-30 mol of ethylene oxide; eg, 1.5-5 pieces. Polyglycerolized fatty amides containing 1.5-4 glycerol groups; sorbitan ethoxylated fatty acid esters containing 2-30 mol of ethylene oxide; plant-derived ethoxylated fatty acid esters; sucrose fatty acid esters; polyethylene glycol fatty acid esters Polyethoxylated fatty acid monoesters or diesters of glycerol (C ₆ to C ₂₄ ) alkyl polyglycosides; N- (C ₆ to C ₂₄ ) alkyl glucamine derivatives; (C ₁₀ to C ₁₄ ) alkyl amine oxides or N-( C ₁₀ to C ₁₄ ) Aminoxides such as acylaminopropylmorpholine oxides; silicone surfactants; and mixtures thereof can also be mentioned.

The nonionic surfactant can preferably be selected from monooxyalkyleneized, polyoxyalkyleneed, monoglycerolized or polyglycerolized nonionic surfactants. More specifically, the oxyalkylene unit is oxyethylene, an oxypropylene unit, or a combination thereof, and is preferably an oxyethylene unit.

Examples of monooxyalkyleneed or polyoxyalkyleneed nonionic surfactants that can be mentioned include:
Monooxyalkylene or polyoxyalkyleneized (C ₈ to C ₂₄ ) alkylphenols,
Saturated or unsaturated, linear or branched, monooxyalkyleneated or polyoxyalkyleneed C ₈ to C ₃₀ alcohols,
Saturated or unsaturated, linear or branched, monooxyalkyleneated or polyoxyalkyleneed C ₈ to C ₃₀ amides,
Saturated or unsaturated, linear or branched C ₈ to C ₃₀ acids and esters of polyalkylene glycols,
Saturated or unsaturated, linear or branched C ₈ to C ₃₀ acids and sorbitol monooxyalkylene or polyoxyalkyleneated esters,
Saturated or unsaturated, monooxyalkylene or polyoxyalkyleneized vegetable oils,
In particular, ethylene oxide and / or propylene oxide condensates, either alone or as a mixture, are included.

Surfactants preferably contain a molar number of ethylene oxide and / or propylene oxide between 1 and 100, most preferably between 2 and 50. According to one of the embodiments of the present invention, the polyoxyalkyleneized nonionic surfactants are polyoxyethylene glycol ether (polyethylene glycol ether of fatty alcohol) and polyoxyethylene glycol ester (polyethylene glycol of fatty acid). Selected from (ester).

Examples of polyoxyethylene saturated fatty alcohols (or C ₈ to C ₃₀ alcohols) that can be mentioned include ethylene oxide adducts of lauryl alcohols, especially those containing 9 to 50 oxyethylene units, more specifically 10 Containing 12 oxyethylene units from (CTFA name Laures-10 to Laures-12); Behenyl alcohol ethylene oxide adducts, especially those containing 9 to 50 oxyethylene units (CTFA name Behenes) -9 to Behenes-50); Ethylene oxide adducts of cetealyl alcohols (mixtures of cetyl and stearyl alcohols), especially those containing 10 to 50 oxyethylene units (CTFA names are ceteares-10 to ceteares-50). ); Ethylene oxide adducts of cetyl alcohols, especially those containing 10 to 50 oxyethylene units (CTFA names are Ceteth-10 to Ceteth-50); Stearyl alcohol ethylene oxide adducts, especially 10 to 50 oxy Those containing ethylene units (CTFA names from Steares-10 to Steares-50); Ethylene oxide adducts of isostearyl alcohols, especially those containing 10 to 50 oxyethylene units (CTFA names from Isosteares-10) Isosteares-50); as well as mixtures thereof.

Examples of polyoxyethylenated unsaturated fatty alcohols (or C ₈ to C ₃₀ alcohols) that can be mentioned are more specific, with ethylene oxide adducts of oleyl alcohol, especially those containing 2 to 50 oxyethylene units. Includes those containing 10 to 40 oxyethylene units (CTFA names: Oles-10 to Oles-40); and mixtures thereof.

Monoglycerolized or polyglycerolized As an example of the nonionic surfactant, monoglycerolized or polyglycerolized C ₈ to C ₄₀ alcohols are preferably used.

In particular, monoglycerolized or polyglycerolized C ₈ to C ₄₀ alcohols have the following formula:
RO- [CH ₂ -CH (CH ₂ OH) -O] _m -H or RO- [CH (CH ₂ OH) -CH ₂ O] _m -H
In the formula, R represents a linear or branched C ₈ to C ₄₀ , preferably C ₈ to C ₃₀ alkyl or alkenyl group, and m is 1 to 30, preferably 1.5. Represents a number in the range of 10.

Examples of suitable compounds in the context of the present invention are lauryl alcohol containing 4 mol of glycerol (INCI name: polyglyceryl-4 lauryl ether), lauryl alcohol containing 1.5 mol of glycerol, and oleyl alcohol containing 4 mol of glycerol (INCI name: polyglyceryl-4 lauryl ether). INCI name: polyglyceryl-4 oleyl ether), oleyl alcohol containing 2 mol of glycerol (INCI name: polyglyceryl-2 oleyl ether), cetearyl alcohol containing 2 mol of glycerol, cetearyl alcohol containing 6 mol of glycerol, 6 mol Oleyl alcohol containing glycerol and octadecanol containing 6 mol of glycerol can be mentioned.

Alcohol can represent a mixture of alcohols in the same way that the value of m represents a statistic, which means that in commercial products, multiple polyglycerolated fatty alcohols can coexist in the form of a mixture. Means that.

Among monoglycerolized or polyglycerolized alcohols, use C ₈ / C ₁₀ alcohols containing 1 mol of glycerol, C ₁₀ / C ₁₂ alcohols containing 1 mol of glycerol and C ₁₂ alcohols containing 1.5 mol of glycerol. It is preferable to do so.

The monoglycerol or polyglycerolized C ₈ to C ₄₀ fatty esters have the following formula:
R'O-[CH ₂ -CH (CH ₂ OR'')-O] _m -R "or R'O- [CH (CH ₂ OR''')-CH ₂ O] _m -R"
In the equation, R', R'' and R'''are independent of each other, and are hydrogen atoms or linear or branched C ₈ to C ₄₀ , preferably C ₈ to C. Represents a ₃₀ alkyl-CO- or alkenyl-CO- group, provided that at least one of R', R'' and R'''is not a hydrogen atom, where m is 1-30, preferably 1.5-10. Represents the number of ranges in.

Examples of polyoxyethyleneylated fatty acid esters that can be mentioned are ethylene oxide adducts with esters of lauric acid, palmitic acid, stearic acid or behenic acid and mixtures thereof, in particular PEG-9 to PEG-50 laurates. (CTFA name: PEG-9 laurate to PEG-50 laurate); PEG-9 palmitate to PEG-50 (CTFA name: PEG-9 palmitate to PEG-50 palmitate); PEG-9 stearate to PEG -50 (CTFA name: PEG-9 stearate to PEG-50 stearate); palmitostearate PEG-9 to PEG-50; behenate PEG-9 to PEG-50 (CTFA name: behenate PEG-9 to PEG-9) PEG-50) behenate; polyethylene glycol monostearate 100EO (CTFA name: PEG-100 stearate); and mixtures thereof.

According to one of the embodiments of the present invention, the nonionic surfactant is a saturated or unsaturated chain containing a polyol and, for example, 8 to 24 carbon atoms, preferably 12 to 22 carbon atoms. Esters with fatty acids having, and preferably polyoxyalkyleneized derivatives thereof containing 10 to 200, more preferably 10 to 100 oxyalkylene units, such as C ₈ to C ₂₄ , preferably C ₁₂ to. A glyceryl ester of the fatty acid of C ₂₂ and its polyoxyalkyleneized derivative containing preferably 10 to 200, more preferably 10 to 100 oxyalkylene units, C ₈ to C ₂₄ , preferably C ₁₂ to C ₂₂ . Sorbitol ester of fatty acid, and its polyoxyalkyleneized derivative containing preferably 10 to 200, more preferably 10 to 100 oxyalkylene units; fatty acids C ₈ to C ₂₄ , preferably C ₁₂ to C ₂₂ Sugar (sculose, maltose, glucose, fructose and / or alkyl glycose) esters and their polyoxyalkyleneized derivatives containing preferably 10-200, more preferably 10-100 oxyalkylene units; ethers of fatty alcohols. You can choose from ethers of sugars with fatty alcohols C ₈ to C ₂₄ , preferably C ₁₂ to C ₂₂ ; as well as mixtures thereof.

As glyceryl esters of fatty acids, glyceryl stearate (mono-, di- and / or glyceryl tristearate) (CTFA name: glyceryl stearate), glyceryl laurate or glyceryl lysinolate, and mixtures thereof can be cited. , Mono-, di- or triesters of fatty acids and polyoxyalkyleneized glycerol as their polyoxyalkyleneized derivatives (mono-, di- or triesters of fatty acids and polyalkylene glycol ethers of glycerol). , Preferably polyoxyethyleneated stearic acid (mono-, di- and / or tristearic acid) glyceryl, eg PEG-20 stearate (mono-, di- and / or tristearic acid) glyceryl can be cited. ..

Mixtures of these surfactants, such as products containing glyceryl stearate and PEG-100 stearate marketed by Uniqema under the name ARLACEL 165, and glyceryl stearate marketed by Goldschmidt under the name TEGIN. Products containing (mono- and glyceryl distearate) and potassium stearate (CTFA name: glyceryl stearate SE) and the like can also be used.

The sorbitol esters of C ₈ to C ₂₄ fatty acids and their polyoxyalkyleneized derivatives are sorbitan palmitate, sorbitan isostearate, sorbitan trioleate; and fatty acids and, for example, alkoxylated sorbitan containing 20 to 100 EOs. Esters, such as sorbitan monostearate (CTFA name: sorbitan stearate) sold by ICI under the name Span 60, sorbitan monopalmitate (CTFA name: palmitic acid) sold by ICI under the name Span 40. Sorbitol), and sorbitan tristearate 20 EO (CTFA name: polysorbate 65), polyethylene sorbitan trioleate (polysorbate 85), sold by ICI under the name Tween 65, or Tween 20 or Tween 60 by Uniqema. It can be selected from the compounds commercially available under the trade name.

Examples of the ester of the fatty acid and glucose or alkyl glucose include alkyl glucose sesquistearate such as glucose palmitate and methyl glucose sesquistearate, alkyl glucose palmitate such as methyl glucose palmitate or ethyl glucose, methyl glucoside fatty ester and methyl glucoside. Diester with oleic acid (CTFA name: methylglucoside dioleate), mixed ester with a mixture of methylglucoside and oleic acid / hydroxystearic acid (CTFA name: dioleic acid / methylglucoside hydroxystearate), methylglucoside and isostearic acid (CTFA name: methylglucoside isostearate), ester of methylglucoside and lauric acid (CTFA name: methylglucoside laurate), monoester of methylglucoside and isostearic acid, and a mixture of diesters (CTFA name: sesquiisostearic acid) Methylglucoside), a mixture of a monoester and diester of methylglucoside and stearic acid (CTFA name: methylglucoside sesquistearate), in particular a product marketed by AMERCHOL under the name Glucate SS, and mixtures thereof are cited. be able to.

As ethoxylated ethers of fatty acids and glucose or alkyl glucose, for example, polyethylene glycol ethers of methyl glucose and stearic acid diesters (CTFA name::) having ethoxylated ethers of fatty acids and methyl glucose, in particular about 20 mol of ethylene oxide. PEG-20 methylglucose distearate), eg a product marketed by AMERCHOL under the name Glucam E-20, polyethylene glycol, a monoester and diester mixture of methylglucose and stearic acid with about 20 mol of ethylene oxide. Ethers (CTFA name: PEG-20 methyl glucose sesquistearate), especially products marketed by AMERCHOL under the name Glucamate SSE-20 and products marketed by GOLD SCHMIDT under the name Grillocose PSE-20, as well as them. A mixture of can be quoted.

As the sucrose ester, for example, palmitostearate saccharose, stearate saccharose and monolaurate sucrose can be cited.

Alkyl glucosides can be used as the sugar ethers, such as decyl glucosides, eg, products marketed by Kao Chemicals under the name MYDOL 10, products marketed by Henkel under the name PLANTAREN 2000, and Lauryl glucoside, such as products marketed by Seppic under the name ORAMIX NS 10, caprylyl / capryl glucoside, such as products marketed by Seppic under the name ORAMIX CG 110 or BASF under the name LUTENSOL GD 70. , For example, products marketed by Henkel under the names PLANTAREN 1200 N and PLANTACARE 1200, coco-glucosides, such as products marketed by Henkel under the name PLANTACARE 818 / UP, and in some cases cetostearyl alcohols. Mixed cetostearyl glucosides, such as those commercially available by Seppic under the name MONTANO V 68, Goldschmidt under the name TEGO-CARE CG90, and Henkel under the name EMULGADE KE3302, such as arachidyl and behenyl alcohol and araki. Arakidyl glucoside marketed by Seppic in the form of a mixture of zir glucosides under the name MONTANO V 202, eg, in the form of a mixture with cetyl and stearyl alcohol (35/65), marketed by Seppic under the name MONTANO V 82. Cocoyl ethyl glucosides, as well as mixtures thereof, can be specifically cited.

Mixtures of glycerides of alkoxylated vegetable oils, such as mixtures of ethoxylated (200 EO) palm and copra (7 EO) glycerides, can also be cited.

The nonionic surfactant according to the present invention preferably contains an alkenyl or a branched C ₁₂ to C ₂₂ acyl chain, such as an oleyl group or an isostearyl group. More preferably, the nonionic surfactant according to the invention is PEG-20 glyceryl triisostearate.

According to one of the embodiments of the present invention, the nonionic surfactant is a copolymer of ethylene oxide and propylene oxide, particularly a copolymer of the following formula:
HO (C ₂ H ₄ O) _a (C ₃ H ₆ O) _b (C ₂ H ₄ O) _c H
(In the formula, a, b and c are integers such that a + c is in the range 2-100 and b is in the range 14-60), and mixtures thereof. ..

According to one of the embodiments of the present invention, the nonionic surfactant can be selected from silicone surfactants. Non-limitingly mentioned are those disclosed in the documents of US Pat. No. 5,364,633 and US Pat. No. 5411744.

The silicone surfactant is preferably prepared by the following formula (I) :.

[During the ceremony,
R ₁ , R ₂ and R ₃ are independent of each other, C ₁ to C ₆ alkyl groups or-(CH ₂ ) _x- (OCH ₂ CH ₂ ) _y- (OCH ₂ CH ₂ CH ₂ ) _z -OR ₄ groups. Represents that at least one group of R ₁ , R ₂ or R ₃ is not an alkyl group and R ₄ is a hydrogen, alkyl or acyl group.
A is an integer in the range 0-200
B is an integer in the range 0-50, but A and B are never 0 at the same time.
x is an integer in the range 1-6
y is an integer from 1 to 30
z is an integer in the range 0-5].

According to a preferred embodiment of the invention, in the compound of formula (I), the alkyl group is a methyl group, x is an integer in the range 2-6 and y is in the range 4-30. Is an integer of.

As an example of the silicone surfactant of the formula (I), the compound of the following formula (II) can be mentioned:

(In the equation, A is an integer in the range 20-10, B is an integer in the range 2-10, and y is an integer in the range 10-20).

As an example of the silicone surfactant of the formula (I), the compound of the following formula (III) can also be mentioned:
H-(OCH ₂ CH ₂ ) _y- (CH ₂ ) ₃ -[(CH ₃ ) _2SiO ] _A' -(CH ₂ ) _3- (OCH ₂ CH ₂ ) _y -OH (III)
(In the formula, A'and y are integers in the range 10-20).

The compounds of the invention that can be used are those sold by Dow Corning under the names DC 5329, DC 7439-146, DC 2-5695 and Q4-3667. The compounds DC 5329, DC 7439-146 and DC 2-5695 have A of 22, B of 2, y of 12, A of 103, B of 10, y of 12, A of 27 and B, respectively. 3, y is 12, a compound of formula (II).

Compound Q4-3667 is a compound of formula (III) in which A is 15 and y is 13.

(Optional additive)
The compositions according to the invention also include, for example, oils, anionic, cationic or amphoteric surfactants, solvents, gums, resins, hydrophilic thickeners, hydrophobic thickeners, dispersants, antioxidants. Membranes, preservatives, fragrances, neutralizers, pH adjusters, disinfectants, UV shields, cosmetic activators other than ingredient (a), such as vitamins, moisturizers, emollients, or collagen protectants, and theirs. May also include any optional additives commonly used in the field of cosmetics, selected from the mixtures of.

As the pH adjuster, at least one acidifying agent and / or at least one basicizing agent (alkaline agent) can be used.

The acidifying agent may be, for example, a mineral acid or an organic acid, such as hydrochloric acid, phosphoric acid, carboxylic acid, such as tartrate, citric acid, and lactic acid, or sulfonic acid.

The acidifying agent may be present in an amount in the range of less than 5% by mass, preferably 3% by mass or less, more preferably 1% or less, based on the total mass of the composition.

The basicizing agent or alkaline agent is, for example, any inorganic or organic basic agent commonly used in cosmetics, such as ammonia; mono, di, and alkanolamines such as tri-ethanolamine, isopropanolamine. Sodium hydroxide and potassium hydroxide; urea, guanidine, and derivatives thereof; basic amino acids such as lysine or arginine; and diamines such as those described in the structure below:

(During the ceremony,
R represents an alkylene such as propylene which is optionally substituted with a hydroxyl or a C ₁ to C ₄ alkyl group, and R ₁ , R ₂ , R ₃ and R ₄ are independently hydrogen atoms and alkyl groups. Alternatively, it represents a C ₁ to C ₄ hydroxyalkyl group, which can be exemplified by 1,3-propanediamine and its derivatives). Arginine, urea, and monoethanolamine may be preferred.

The composition according to the present invention may contain at least one water-miscible solvent such as a lower monoalcohol containing 1 to 5 carbon atoms, a C ₃ to C ₄ ketone, or a C ₃ to C ₄ aldehyde. A water-miscible solvent that can be preferably used is ethanol. The content of the water-miscible solvent may be in the range of 0.1% by mass to 15% by mass, and even better, 1% by mass to 8% by mass with respect to the total mass of the composition.

It is common practice for those skilled in the art to adjust the properties and amounts of the above optional additives that may be present in the composition according to the invention so that the desired cosmetic properties are not affected by the additive.

[Preparation]
The composition according to the present invention can be prepared by mixing the above-mentioned essential components and optional components by a conventional method.

For example, the composition according to the present invention is
(a) At least one ellagic acid compound and
(b) At least one phosphate compound and
(c) At least one metal oxide and
It can be prepared by a method comprising the step of (d) mixing with water, whereby the amount of (a) the ellagic acid compound in the composition is 0.1% by mass or more with respect to the total mass of the composition.

It is possible to further mix any of the optional components.

It is more preferable to first mix (a) an ellagic acid compound, (b) a phosphoric acid compound and (d) water, and then further mix the mixture with (c) a metal oxide to obtain the composition according to the present invention. There is.

The mixing can be carried out at any temperature such as room temperature (for example, 20 to 25 ° C., preferably 25 ° C.), preferably 30 ° C. or higher, preferably 40 ° C. or higher, and more preferably 50 ° C. or higher. It may be preferable to further mix with any of the above-mentioned optional components such as a pH adjuster.

The form of the composition according to the present invention is not particularly limited, and various forms such as W / O emulsion, O / W emulsion, gel, and solution can be taken. The composition according to the invention may preferably be in the form of an O / W emulsion.

[Cosmetology method]
The composition according to the invention can be used as a cosmetic or dermatological composition, preferably a cosmetic composition, more preferably a cosmetic composition for a keratin substance. Examples of the keratin substance include skin, scalp, hair, mucous membranes such as lips, and nails.

The compositions according to the invention can be used as antioxidant, whitening or antibacterial products for keratinous substances such as skin. In particular, the composition according to the present invention can be used as a whitening product.

The compositions according to the invention may preferably be intended for application to keratinous substances such as skin, scalp and / or lips, preferably skin.

Therefore, the compositions according to the invention can be used in cosmetic methods for keratinous substances, preferably skin. In one embodiment, the invention relates to a keratin substance, preferably a cosmetic method for the skin, preferably a whitening method, comprising the step of applying the composition according to the invention to the keratin substance.

The compositions according to the invention can be used as topical cosmetic compositions in the form of lotions, milk lotions, creams, gels, pastes, serums, foams, or sprays.

[How to stabilize the color]
The present invention also comprises (a) at least one ellagic acid compound, (c) at least one metal oxide, and (d) a change in color of the composition comprising water, preferably a change in color over time. More preferably, it is a method of preventing or reducing a change in color to yellow or brown over time, and also relates to a method comprising (b) adding at least one phosphoric acid compound to the composition.

The amount of (a) ellagic acid compound in the above composition may be 0.1% by mass or more with respect to the total mass of the composition.

The description of (a) ellagic acid compound, (b) phosphoric acid compound, (c) metal oxide and (d) water of the composition according to the present invention is applied to the above-mentioned method for stabilizing color according to the present invention. Can be done.

The composition used for use with this composition may contain any of the optional components described above with respect to the composition according to the invention.

[use]
The present invention also comprises (a) at least one ellagic acid compound, (c) at least one metal oxide, and (d) a change in color of the composition comprising water, preferably a change in color over time. More preferably, it also relates to (b) the use of at least one phosphate compound to prevent or reduce the color change to yellow or brown over time.

The amount of (a) ellagic acid compound in the above composition may be 0.1% by mass or more with respect to the total mass of the composition.

The description of (a) ellagic acid compound, (b) phosphoric acid compound, (c) metal oxide and (d) water of the composition according to the present invention can be applied to the use according to the present invention.

The composition used for use with this composition may contain any of the optional components described above with respect to the composition according to the invention.

The present invention will be described in more detail by way of examples. However, these examples should not be construed as limiting the scope of the invention.

(Examples 1 to 4 and comparative examples 1 to 7)
[Preparation]
The compositions according to Examples 1 to 4 and Comparative Examples 1 to 7 were prepared by mixing the components shown in Table 1, respectively. All numerical values for the amount of ingredients are based on the "mass%" of the active ingredient.

[evaluation]
(Stability)
Stability of each composition according to Examples 1 to 4 and Comparative Examples 1 to 7:
(1) Measuring the "b" value (initial) immediately after preparation of the composition, and
(2) Measuring the "b" value (after 2 weeks) of the composition maintained at 45 ° C for 2 weeks,
(3) Determining Δb by the difference between the "b" value (initial) and the "b" value (after 2 weeks),
(4) Evaluated by classifying Δb based on the following criteria.

Measurements (1) and (2) were performed using a chromaticity meter (Konica Minolta, CM-700d, portable spectrophotometer).

Excellent: Δb <1.0
Good: 1.0 ≤ Δb <2.0
Defective: 2.0 ≤ Δb

The results of the stability evaluation are shown in Table 1.

In Examples 1 and 2, the composition according to Examples 1 and 2 containing a phosphoric acid compound (potassium cetyl phosphate) can prevent or reduce the color change of the composition over time. show.

Example 3 shows that the composition according to Example 3 containing another phosphoric acid compound (Ceteth-10 phosphoric acid) can prevent or reduce the color change of the composition over time. show.

Example 4 shows that the composition according to Example 4 containing another phosphoric acid compound (dipotassium phosphate) can prevent or reduce the color change of the composition over time. ..

Comparative Examples 1 and 2 show that the composition according to Comparative Examples 1 and 2 containing no phosphoric acid compound cannot prevent or reduce the color change of the composition over time.

Comparative Examples 1 and 2 also show that the change in color over time is caused not only by the coating of titanium oxide in the form of particles, but also by the coating of other particles such as mica.

In Comparative Example 3, the composition according to Comparative Example 3 containing an anionic surfactant (sodium lauryl sulfate) instead of the phosphoric acid compound cannot prevent or reduce the color change of the composition over time. Indicates that it cannot be done.

In Comparative Example 4, the composition according to Comparative Example 4 containing another anionic surfactant (sodium cocoylglycine) instead of the phosphoric acid compound cannot prevent the color change of the composition over time, or Indicates that it cannot be reduced.

In Comparative Example 5, the composition according to Comparative Example 5 containing a cationic surfactant (palmitamidopropyltrimonium chloride) instead of the phosphoric acid compound cannot prevent the color change of the composition over time. , Or indicates that it cannot be reduced.

In Comparative Example 6, the composition according to Comparative Example 6 containing another cationic surfactant (cetrimonium chloride) instead of the phosphoric acid compound cannot prevent the color change of the composition over time, or Indicates that it cannot be reduced.

In Comparative Example 7, the composition according to Comparative Example 7 containing an amphoteric tenside (cocamidopropyl betaine) instead of the phosphoric acid compound cannot prevent or reduce the color change of the composition over time. Indicates that it cannot be done.

In Examples 1 to 4 and Comparative Examples 1 to 7, the color change of the composition in which the phosphoric acid compound contains an ellagic acid compound, a metal oxide, and water, preferably a change in color over time, more preferably over time. Demonstrate that the color change to yellow or brown can be prevented or reduced.

Claims (7)

(a) At least one ellagic acid compound and
(b) At least one phosphate compound and
(c) At least one metal oxide and
(d) A composition containing water.
The amount of the (a) ellagic acid compound in the composition is 0.1 to 5 % by mass with respect to the total mass of the composition.
The (b) phosphoric acid compound is selected from the group consisting of potassium cetyl phosphate, ceteth-10 phosphate, dipotassium phosphate, and mixtures thereof.
The amount of the (b) phosphoric acid compound in the composition is 0.01 to 20% by mass with respect to the total mass of the composition.
The (c) metal oxide is selected from the group consisting of titanium dioxide, mica (and) titanium dioxide, and mixtures thereof.
A composition in which the amount of the (c) metal oxide in the composition is 0.1 to 30% by mass with respect to the total mass of the composition. The composition according to claim 1, wherein the amount of the (a) ellagic acid compound in the composition is 0.2 to 1% by mass with respect to the total mass of the composition. The composition according to claim 1 or 2 , wherein the amount of the (b) phosphoric acid compound in the composition is 0.05 to 10% by mass with respect to the total mass of the composition. The composition according to any one of claims 1 to 3 , wherein the composition (c) is not coated with a metal oxide. The composition according to any one of claims 1 to 4 , wherein the (c) metal oxide is present in the coating of the particles . The composition according to any one of claims 1 to 5 , wherein the amount of the (c) metal oxide in the composition is 0.5 to 20% by mass with respect to the total mass of the composition. The composition according to any one of claims 1 to 6 , wherein the amount of (d) water in the composition is 50 to 90% by mass with respect to the total mass of the composition.