JP7049683B2 - トラピジルを使用する錐体外路症候群の処置 - Google Patents

トラピジルを使用する錐体外路症候群の処置 Download PDF

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JP7049683B2
JP7049683B2 JP2019502544A JP2019502544A JP7049683B2 JP 7049683 B2 JP7049683 B2 JP 7049683B2 JP 2019502544 A JP2019502544 A JP 2019502544A JP 2019502544 A JP2019502544 A JP 2019502544A JP 7049683 B2 JP7049683 B2 JP 7049683B2
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per day
trapidil
pharmaceutically acceptable
acid
cases
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JP2019510826A5 (https=
JP2019510826A (ja
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ボードバー，アーラッシュ
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シノピア バイオサイエンシーズ，インク．
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Nutrition Science (AREA)
  • Psychiatry (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Catching Or Destruction (AREA)
JP2019502544A 2016-04-04 2017-04-03 トラピジルを使用する錐体外路症候群の処置 Active JP7049683B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022044284A JP7794668B2 (ja) 2016-04-04 2022-03-18 トラピジルを使用する錐体外路症候群の処置
JP2024041690A JP2024095682A (ja) 2016-04-04 2024-03-15 トラピジルを使用する錐体外路症候群の処置

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662317983P 2016-04-04 2016-04-04
US62/317,983 2016-04-04
PCT/US2017/025788 WO2017176652A2 (en) 2016-04-04 2017-04-03 Treating extrapyramidal syndrome using trapidil

Related Child Applications (1)

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JP2022044284A Division JP7794668B2 (ja) 2016-04-04 2022-03-18 トラピジルを使用する錐体外路症候群の処置

Publications (3)

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JP2019510826A JP2019510826A (ja) 2019-04-18
JP2019510826A5 JP2019510826A5 (https=) 2020-05-14
JP7049683B2 true JP7049683B2 (ja) 2022-04-07

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JP2019502544A Active JP7049683B2 (ja) 2016-04-04 2017-04-03 トラピジルを使用する錐体外路症候群の処置
JP2022044284A Active JP7794668B2 (ja) 2016-04-04 2022-03-18 トラピジルを使用する錐体外路症候群の処置
JP2024041690A Pending JP2024095682A (ja) 2016-04-04 2024-03-15 トラピジルを使用する錐体外路症候群の処置

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JP2024041690A Pending JP2024095682A (ja) 2016-04-04 2024-03-15 トラピジルを使用する錐体外路症候群の処置

Country Status (10)

Country Link
US (4) US10350212B2 (https=)
EP (1) EP3442538B1 (https=)
JP (3) JP7049683B2 (https=)
CN (2) CN116509869A (https=)
AU (1) AU2017246334C1 (https=)
CA (1) CA3054674A1 (https=)
DK (1) DK3442538T3 (https=)
ES (1) ES3039958T3 (https=)
FI (1) FI3442538T3 (https=)
WO (1) WO2017176652A2 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7049683B2 (ja) 2016-04-04 2022-04-07 シノピア バイオサイエンシーズ，インク． トラピジルを使用する錐体外路症候群の処置
US11517548B2 (en) 2018-07-19 2022-12-06 Impel Pharmaceuticals Inc. Respiratory tract delivery of levodopa and DOPA decarboxylase inhibitor for treatment of Parkinson's Disease
CA3163242A1 (en) * 2019-12-02 2021-06-10 Aarash BORDBAR Treating cognitive disorders using trapidil
MX2022011879A (es) * 2020-03-26 2023-01-11 Sinopia Biosciences Inc Derivados de trapidilo marcados isotopicamente.
WO2024053728A1 (ja) * 2022-09-09 2024-03-14 住友ファーマ株式会社 対象の状態の予測およびその応用
CN116754348B (zh) * 2023-06-06 2024-03-08 华北理工大学 基于zif-8-90材料的泡腾片、其制备方法及其应用

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Publication number Publication date
US11628170B2 (en) 2023-04-18
AU2017246334B2 (en) 2022-07-28
WO2017176652A3 (en) 2018-05-17
AU2017246334C1 (en) 2022-11-17
FI3442538T3 (fi) 2025-09-04
US20250387396A1 (en) 2025-12-25
ES3039958T3 (en) 2025-10-27
EP3442538A2 (en) 2019-02-20
US20230201205A1 (en) 2023-06-29
JP2022088469A (ja) 2022-06-14
EP3442538B1 (en) 2025-07-23
WO2017176652A2 (en) 2017-10-12
CN109310700A (zh) 2019-02-05
AU2017246334A1 (en) 2018-11-15
JP2024095682A (ja) 2024-07-10
DK3442538T3 (da) 2025-09-01
EP3442538A4 (en) 2019-11-20
US20180243307A1 (en) 2018-08-30
US12268691B2 (en) 2025-04-08
CN116509869A (zh) 2023-08-01
JP2019510826A (ja) 2019-04-18
US10350212B2 (en) 2019-07-16
JP7794668B2 (ja) 2026-01-06
CA3054674A1 (en) 2017-12-10
US20190328741A1 (en) 2019-10-31

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