JP7046793B2 - 薬物送達のための浸透促進剤を含む組成物 - Google Patents

薬物送達のための浸透促進剤を含む組成物 Download PDF

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JP7046793B2
JP7046793B2 JP2018506186A JP2018506186A JP7046793B2 JP 7046793 B2 JP7046793 B2 JP 7046793B2 JP 2018506186 A JP2018506186 A JP 2018506186A JP 2018506186 A JP2018506186 A JP 2018506186A JP 7046793 B2 JP7046793 B2 JP 7046793B2
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acid
optionally substituted
matrix
sodium
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JP2018522905A (ja
JP2018522905A5 (https=
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コヘイン,ダニエル,エス.
ヤン,ロン
リン,リリー,ユン
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Boston Childrens Hospital
Massachusetts Institute of Technology
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Massachusetts Institute of Technology
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    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • A61K31/425Thiazoles
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    • A61K31/431Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
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    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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JP2018506186A 2015-08-05 2016-08-05 薬物送達のための浸透促進剤を含む組成物 Active JP7046793B2 (ja)

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US201562201199P 2015-08-05 2015-08-05
US62/201,199 2015-08-05
PCT/US2016/045908 WO2017024282A1 (en) 2015-08-05 2016-08-05 Compositions with permeation enhancers for drug delivery

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US (2) US11110175B2 (https=)
EP (1) EP3331547A4 (https=)
JP (2) JP7046793B2 (https=)
KR (1) KR102826997B1 (https=)
CN (1) CN108135967B (https=)
AU (1) AU2016304585B2 (https=)
BR (1) BR112018002227A2 (https=)
CA (1) CA2994702A1 (https=)
CL (1) CL2018000299A1 (https=)
CO (1) CO2018001407A2 (https=)
CR (1) CR20180128A (https=)
EA (1) EA201890458A1 (https=)
EC (1) ECSP18017254A (https=)
HK (1) HK1252531A1 (https=)
IL (1) IL257329A (https=)
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PE (1) PE20181153A1 (https=)
PH (1) PH12018500262A1 (https=)
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JP2019512447A (ja) * 2016-03-31 2019-05-16 ダウ グローバル テクノロジーズ エルエルシー 疎水性シリカ粒子の作製方法
CN109937033A (zh) * 2016-09-14 2019-06-25 儿童医学中心公司 用于药物递送的具有渗透增强剂的组合物
US11173210B2 (en) * 2017-10-24 2021-11-16 Sonoran Biosciences, Inc. Temperature-responsive degradable hydrogels
CN112020359A (zh) 2018-02-09 2020-12-01 分贝治疗公司 含有抗铂化学保护剂的高渗药物组合物
WO2019193513A1 (en) * 2018-04-03 2019-10-10 Hyderabad Eye Research Foundation Mucoadhesive drug delivery system for ocular administration of fluoroquinolone antibiotics
AU2019321429B2 (en) 2018-08-15 2022-12-08 Aiviva Biopharma, Inc. Multi-kinase inhibitors of VEGF and TGF beta and uses thereof
CA3110566A1 (en) * 2018-08-31 2020-03-05 Children's Medical Center Corporation Compositions with synergistic permeation enhancers for drug delivery
AU2019386968B2 (en) * 2018-11-26 2022-12-22 Aiviva Biopharma, Inc. Pharmaceutical biodissolvable gels for drug delivery
CN109513036B (zh) * 2019-01-11 2021-04-20 四川大学 一种受体温诱导可自动关闭抗菌功能的胶原蛋白材料
CN111840553A (zh) * 2019-04-15 2020-10-30 湖州依诺唯新药物制剂有限公司 脂性药物制剂及其应用
CN110028624A (zh) * 2019-04-16 2019-07-19 昆明理工大学 基于半纤维素复合温敏凝胶的制备方法及应用
CN114040782A (zh) 2019-04-30 2022-02-11 威斯康星州医药大学股份有限公司 跨鼓膜递送平台及其用途
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CA3188400A1 (en) * 2020-08-03 2022-02-10 Daniel S. Kohane Thermo-sensitive permeation enhancing formulations for drug delivery
CN111849597B (zh) * 2020-08-04 2022-08-09 中山华明泰科技股份有限公司 一种烷烃煤基油合成润滑剂的制备方法和应用
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