JP7038100B2 - マイクロ流体デバイスでのｔリンパ球の選別 - Google Patents

マイクロ流体デバイスでのｔリンパ球の選別 Download PDF

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JP7038100B2
JP7038100B2 JP2019502710A JP2019502710A JP7038100B2 JP 7038100 B2 JP7038100 B2 JP 7038100B2 JP 2019502710 A JP2019502710 A JP 2019502710A JP 2019502710 A JP2019502710 A JP 2019502710A JP 7038100 B2 JP7038100 B2 JP 7038100B2
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microns
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microfluidic device
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JP2019528684A (ja
JP2019528684A5 (enExample
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ディー． ルーサーバック，ケビン
ブロネヴェツキー，エレーナ
ジェー． ビーミラー，ピーター
ワン，シャオフア
ティー． チャップマン，ケヴィン
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バークレー ライツ，インコーポレイテッド
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
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    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652—Sorting or classification of particles or molecules
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    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
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  • Animal Behavior & Ethology (AREA)
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  • Developmental Biology & Embryology (AREA)
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  • General Physics & Mathematics (AREA)
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  • Biotechnology (AREA)
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  • Electrochemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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JP2019502710A 2016-07-21 2017-07-21 マイクロ流体デバイスでのｔリンパ球の選別 Expired - Fee Related JP7038100B2 (ja)

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US201662365372P 2016-07-21 2016-07-21
US62/365,372 2016-07-21
PCT/US2017/043395 WO2018018017A1 (en) 2016-07-21 2017-07-21 Sorting of t lymphocytes in a microfluidic device

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US (1) US11666912B2 (enExample)
EP (1) EP3487510B1 (enExample)
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KR (1) KR102456488B1 (enExample)
CN (1) CN109952106B (enExample)
AU (1) AU2017298545B2 (enExample)
CA (1) CA3030748C (enExample)
IL (1) IL264306B2 (enExample)
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CN110382439B (zh) 2016-12-30 2026-07-21 埃克切拉生物科学公司 多级样品回收系统
US11213824B2 (en) 2017-03-29 2022-01-04 The Research Foundation For The State University Of New York Microfluidic device and methods
JP7227162B2 (ja) 2017-06-06 2023-02-21 ザイマージェン インコーポレイテッド 真菌株を改良するためのｈｔｐゲノム操作プラットフォーム
TWI804560B (zh) * 2018-01-11 2023-06-11 美商奈諾卡福有限責任公司 微流體細胞裝置及其使用的方法
WO2019236848A1 (en) 2018-06-06 2019-12-12 Zymergen Inc. Manipulation of genes involved in signal transduction to control fungal morphology during fermentation and production
DE102018210665A1 (de) * 2018-06-29 2020-01-02 Robert Bosch Gmbh Mikrofluidische Flusszelle und Verfahren zur Separierung von Zellen
KR20210063362A (ko) 2018-09-21 2021-06-01 버클리 라잇츠, 인크. 작용화된 웰 플레이트, 이의 제조 및 사용 방법
DK3890876T3 (da) 2018-12-06 2024-07-22 Xcella Biosciences Inc Lateral påfyldning af mikrokapillære arrays
GB201910035D0 (en) * 2019-07-12 2019-08-28 Lightcast Discovery Ltd Apparatus and methods for manipulating microdroplets
CN110468048B (zh) * 2019-09-16 2022-09-02 许中伟 基于微流控系统控制生产工程化免疫细胞的微型化设备和方法
US20220390436A1 (en) * 2019-10-25 2022-12-08 Scribe Biosciences T-cell receptor neoantigen interaction analysis via microfluidics
CA3156776A1 (en) 2019-11-08 2021-05-14 xCella Biosciences, Inc. Apparatus and methods for laser-based single cell recovery from microcapillary arrays
CA3157616A1 (en) 2019-11-17 2021-05-20 Darshan THAKER Systems and methods for analyses of biological samples
JP7660123B2 (ja) 2019-12-27 2025-04-10 ベックマン コールター， インコーポレイテッド サンプル調製器具
US11479779B2 (en) 2020-07-31 2022-10-25 Zymergen Inc. Systems and methods for high-throughput automated strain generation for non-sporulating fungi
KR102388470B1 (ko) 2020-12-01 2022-04-21 단국대학교 천안캠퍼스 산학협력단 실리콘계 나노 플레이트 제조방법, 및 실리콘계 나노플레이트를 포함하는 음극재
US20220193674A1 (en) * 2020-12-23 2022-06-23 Imec Vzw Microfluidic Device Unit
CN117916021A (zh) * 2021-06-30 2024-04-19 康特姆斯集团有限公司 使用介电泳浓缩流体样本中的目标微粒的微流体设备
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