JP7029172B2 - 骨量減少と関連する疾病を治療又は予防し、骨格構造及び生体力学的骨強度を改善する組成物 - Google Patents

骨量減少と関連する疾病を治療又は予防し、骨格構造及び生体力学的骨強度を改善する組成物 Download PDF

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JP7029172B2
JP7029172B2 JP2018228252A JP2018228252A JP7029172B2 JP 7029172 B2 JP7029172 B2 JP 7029172B2 JP 2018228252 A JP2018228252 A JP 2018228252A JP 2018228252 A JP2018228252 A JP 2018228252A JP 7029172 B2 JP7029172 B2 JP 7029172B2
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王上達
許宸
蘇南維
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休斯生物科技股▲ふん▼有限公司
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    • A—HUMAN NECESSITIES
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    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/52—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an inorganic compound, e.g. an inorganic ion that is complexed with the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration

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  • Health & Medical Sciences (AREA)
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JP2018228252A 2017-12-07 2018-12-05 骨量減少と関連する疾病を治療又は予防し、骨格構造及び生体力学的骨強度を改善する組成物 Active JP7029172B2 (ja)

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US201762595697P 2017-12-07 2017-12-07
US62/595,697 2017-12-07

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JP2019099579A JP2019099579A (ja) 2019-06-24
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JP7029172B2 true JP7029172B2 (ja) 2022-03-03

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WO2025117337A1 (en) * 2023-11-28 2025-06-05 GreenStone Biosciences, Inc. Genistein phosphate derivatives
CN118359663B (zh) * 2024-04-26 2024-12-13 西安交通大学医学院第一附属医院 线粒体靶向染料木素衍生物及其在制备抗心肌缺血再灌注损伤药物中的应用

Citations (2)

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WO1999063995A1 (en) 1998-06-12 1999-12-16 Vyrex Corporation Isoflavone derivatives
US20020111466A1 (en) 2000-12-15 2002-08-15 Hendler Sheldon S. Isoflavone derivatives

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Publication number Priority date Publication date Assignee Title
WO2005049627A1 (en) * 2003-11-18 2005-06-02 Novogen Research Pty Ltd Isoflavonoid prodrugs, compositions thereof and therapeutic methods involving same
KR20100051829A (ko) * 2007-07-31 2010-05-18 리머릭 바이오파르마 인코오포레이티드 인산화된 피론 유사체 및 방법
TR201004464A2 (tr) * 2010-06-03 2012-11-21 B�Lg�� Mahmut Kemik erimesi için formülasyon.
US8900635B2 (en) * 2010-11-15 2014-12-02 Humanetics Corporation Nanoparticle isoflavone compositions and methods of making and using the same
CN102351828A (zh) * 2011-08-16 2012-02-15 李荣立 一种提取金雀异黄素的新工艺
CN102488210B (zh) * 2011-12-27 2013-06-19 西南大学 染料木素水凝胶的复合物及其制备方法
CN105381470B (zh) * 2015-11-27 2018-11-02 广东医科大学 一种改性染料木素及其应用
TWI670374B (zh) * 2016-04-25 2019-09-01 國立臺灣大學 具有苯並吡喃酮類磷酸酯合成酶活性之多肽、包含編碼該多肽之核酸序列之微生物及苯並吡喃酮類磷酸酯衍生物之製備方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999063995A1 (en) 1998-06-12 1999-12-16 Vyrex Corporation Isoflavone derivatives
US20020111466A1 (en) 2000-12-15 2002-08-15 Hendler Sheldon S. Isoflavone derivatives

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
「新医薬品の臨床評価に関する一般指針について」（薬新薬第四三号）各都道府県衛生主管部局長あて厚生省薬務局新医薬品課長通知，1992年，第１－１２頁
Guidance for Industry, Estimating the Maximum Safe Starting Dose in Initial Clinical Trials for Therapeutics in Adult Healthy Volunteers，U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER)，2005年，pp. 1-27
J Bone Miner Metab，2002年，Vol. 20，pp. 148-155
JOURNAL OF FUNCTIONAL FOODS，2015年，Vol. 13，pp. 323-335
Trace Nutrients Research，2010年，Vol. 27，pp. 35-38
日本内科学会雑誌，2005年，Vol. 94, No. 4，pp. 670-674 (pp. (64)-(68))
日本比較内分泌学会ニュース，2001年，Vol. 2001, No. 101，pp. 18-20
臨床薬理，2000年，Vol. 31, No. 3，pp. 539-540
順天堂医学，2004年，Vol. 49, No. 4，pp. 440-444

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TWI756495B (zh) 2022-03-01
US20190175545A1 (en) 2019-06-13
KR102376603B1 (ko) 2022-03-18
EP3494973A1 (en) 2019-06-12
JP2019099579A (ja) 2019-06-24
US10881634B2 (en) 2021-01-05
CN109939118A (zh) 2019-06-28
EP3494973B1 (en) 2021-07-28
KR20190067695A (ko) 2019-06-17
TW201924691A (zh) 2019-07-01

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