JP7026098B2 - 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析 - Google Patents

子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析 Download PDF

Info

Publication number
JP7026098B2
JP7026098B2 JP2019503634A JP2019503634A JP7026098B2 JP 7026098 B2 JP7026098 B2 JP 7026098B2 JP 2019503634 A JP2019503634 A JP 2019503634A JP 2019503634 A JP2019503634 A JP 2019503634A JP 7026098 B2 JP7026098 B2 JP 7026098B2
Authority
JP
Japan
Prior art keywords
fetal
cells
dna
isolated
maternal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2019503634A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019516398A5 (https=
JP2019516398A (ja
Inventor
ドリューロ，サッシャ
アルマン，ランドール，ディー．
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wayne State University
Original Assignee
Wayne State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wayne State University filed Critical Wayne State University
Publication of JP2019516398A publication Critical patent/JP2019516398A/ja
Publication of JP2019516398A5 publication Critical patent/JP2019516398A5/ja
Priority to JP2021187537A priority Critical patent/JP2022028827A/ja
Application granted granted Critical
Publication of JP7026098B2 publication Critical patent/JP7026098B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2019503634A 2016-04-06 2017-04-06 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析 Active JP7026098B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021187537A JP2022028827A (ja) 2016-04-06 2021-11-18 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662318982P 2016-04-06 2016-04-06
US62/318,982 2016-04-06
PCT/US2017/026335 WO2017176985A1 (en) 2016-04-06 2017-04-06 Isolation and analysis of fetal dna from extravillous trophoblast cells retrieved from the endocervical canal

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021187537A Division JP2022028827A (ja) 2016-04-06 2021-11-18 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析

Publications (3)

Publication Number Publication Date
JP2019516398A JP2019516398A (ja) 2019-06-20
JP2019516398A5 JP2019516398A5 (https=) 2020-07-27
JP7026098B2 true JP7026098B2 (ja) 2022-02-25

Family

ID=60001444

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019503634A Active JP7026098B2 (ja) 2016-04-06 2017-04-06 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析
JP2021187537A Withdrawn JP2022028827A (ja) 2016-04-06 2021-11-18 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021187537A Withdrawn JP2022028827A (ja) 2016-04-06 2021-11-18 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析

Country Status (6)

Country Link
US (1) US10808239B2 (https=)
EP (1) EP3440209A4 (https=)
JP (2) JP7026098B2 (https=)
CN (1) CN109312332B (https=)
AU (1) AU2017246480B2 (https=)
WO (1) WO2017176985A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017180909A1 (en) 2016-04-13 2017-10-19 Nextgen Jane, Inc. Sample collection and preservation devices, systems and methods
AU2018355575A1 (en) 2017-10-27 2020-05-21 Juno Diagnostics, Inc. Devices, systems and methods for ultra-low volume liquid biopsy
AU2019205809A1 (en) * 2018-01-08 2020-08-13 Cradle Genomics, Inc. Methods and kits for nucleic acid isolation
US12462935B2 (en) 2018-03-30 2025-11-04 Nucleix Ltd. Deep learning-based methods, devices, and systems for prenatal testing
EP3730627A1 (en) * 2019-04-25 2020-10-28 Kiadis Pharma Intellectual Property BV Method for donor identity verification
CN112980779B (zh) * 2021-05-20 2021-08-24 广州凯普医药科技有限公司 一种从孕妇宫颈脱落细胞中分离胎盘滋养层细胞的方法
CN113234163B (zh) * 2021-07-13 2021-11-02 北京贝瑞和康生物技术有限公司 分离胎儿滋养层细胞的方法及试剂盒
CN116103388B (zh) * 2022-12-23 2024-01-23 北京大学第三医院（北京大学第三临床医学院） 一种用于着床前胚胎atxn3基因检测的试剂盒、系统和方法
KR102894686B1 (ko) 2023-05-08 2025-12-03 인제대학교 산학협력단 융모막 검사용 자동 검체 채취 장치
CN116445590A (zh) * 2023-05-24 2023-07-18 浙江大学医学院附属第一医院 一种基于he染色进行妊娠物基因分型的方法
CN117174273B (zh) * 2023-11-01 2024-02-23 南京金域医学检验所有限公司 一种用于肾穿刺活检的免疫荧光数据处理方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009531033A (ja) 2006-03-23 2009-09-03 バイオセプト インコーポレイティッド 胎児栄養膜の単離
WO2010121294A1 (en) 2009-04-21 2010-10-28 Genetic Technologies Limited Methods for obtaining fetal genetic material

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629147A (en) 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
EP0587951B1 (en) 1992-09-18 1997-12-17 AMERSHAM INTERNATIONAL plc Cell nuclei capture method and device used therefor
WO1999041613A1 (en) 1998-02-12 1999-08-19 Immunivest Methods and reagents for the rapid and efficient isolation of circulating cancer cells
AUPR749901A0 (en) 2001-09-06 2001-09-27 Monash University Method of identifying chromosomal abnormalities and prenatal diagnosis
US20050181429A1 (en) 2003-04-03 2005-08-18 Monaliza Medical Ltd. Non-invasive prenatal genetic diagnosis using transcervical cells
US20040197832A1 (en) 2003-04-03 2004-10-07 Mor Research Applications Ltd. Non-invasive prenatal genetic diagnosis using transcervical cells
DK2299275T3 (en) 2004-07-30 2018-05-07 Adeza Biomedical Corp Classification of oncofetal fetronectin level for pregnancy-related indications
US20090286271A1 (en) 2006-05-31 2009-11-19 Karumanchi Ananth S Methods of Diagnosing and Treating Complications of Pregnancy
CA2713545A1 (en) * 2008-01-30 2009-08-06 Novartis Ag Two stage enrichment of cell-free fetal dna in maternal plasma
WO2009103110A1 (en) 2008-02-18 2009-08-27 Genetic Technologies Limited Cell processing and/or enrichment methods
CA2888746C (en) * 2012-10-19 2022-07-26 Wayne State University Identification and analysis of fetal trophoblast cells in cervical mucus for prenatal diagnosis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009531033A (ja) 2006-03-23 2009-09-03 バイオセプト インコーポレイティッド 胎児栄養膜の単離
WO2010121294A1 (en) 2009-04-21 2010-10-28 Genetic Technologies Limited Methods for obtaining fetal genetic material

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JAIN, Chandni V.，Molecular Regulation Of Trophoblast Survival During Placentation And Pathologies Of Placental Insufficiency，Wayne State University Dissertations，1642，2016年01月01日，https://digitalcommons.wayne.edu/cgi/viewcontent.cgi?article=2641&context=oa_dissertations

Also Published As

Publication number Publication date
CA3019953A1 (en) 2017-10-12
WO2017176985A8 (en) 2018-11-15
US20190153431A1 (en) 2019-05-23
AU2017246480B2 (en) 2023-06-01
AU2017246480A8 (en) 2018-12-06
CN109312332B (zh) 2022-07-08
WO2017176985A1 (en) 2017-10-12
CN109312332A (zh) 2019-02-05
EP3440209A1 (en) 2019-02-13
US10808239B2 (en) 2020-10-20
JP2019516398A (ja) 2019-06-20
AU2017246480A1 (en) 2018-10-25
EP3440209A4 (en) 2019-11-27
JP2022028827A (ja) 2022-02-16

Similar Documents

Publication Publication Date Title
JP7026098B2 (ja) 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析
US20240384256A1 (en) Methods and compositions for the extraction and amplification of nucleic acid from a sample
EP3099818A1 (en) Preimplantation assessment of embryos through detection of free embryonic dna
US10161005B2 (en) Method for detecting telomerase via washing-free anchored-extension and telomeric-binding amplification, and kit
CN118284703A (zh) 胚胎核酸分析
CA3019953C (en) Isolation and analysis of fetal dna from extravillous trophoblast cells retrieved from the endocervical canal
US20200149103A1 (en) Methods and devices for sample collection and analysis
HK40018177A (en) Kit for the extraction and amplification of nucleic acid from a sample
HK40018177B (en) Kit for the extraction and amplification of nucleic acid from a sample
HK1247966A1 (en) Methods for the extraction of nucleic acid from a sample
HK1247966B (en) Methods for the extraction of nucleic acid from a sample
HK40036559A (en) Methods and kits for nucleic acid isolation
HK1128734B (en) Methods and compositions for the extraction of nucleic acid from a sample
HK1128734A (en) Methods and compositions for the extraction of nucleic acid from a sample

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190116

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20181023

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20200110

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20200615

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20201210

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20201216

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20210315

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210331

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20210721

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20211118

C60 Trial request (containing other claim documents, opposition documents)

Free format text: JAPANESE INTERMEDIATE CODE: C60

Effective date: 20211118

C11 Written invitation by the commissioner to file amendments

Free format text: JAPANESE INTERMEDIATE CODE: C11

Effective date: 20211201

C876 Explanation why request for accelerated appeal examination is justified

Free format text: JAPANESE INTERMEDIATE CODE: C876

Effective date: 20211222

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20211217

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20220112

C21 Notice of transfer of a case for reconsideration by examiners before appeal proceedings

Free format text: JAPANESE INTERMEDIATE CODE: C21

Effective date: 20220119

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20220126

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20220214

R150 Certificate of patent or registration of utility model

Ref document number: 7026098

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250