CN109312332B - 自子宫颈内管获取的绒毛外滋养层细胞的胎儿dna的分离与分析 - Google Patents

自子宫颈内管获取的绒毛外滋养层细胞的胎儿dna的分离与分析 Download PDF

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CN109312332B
CN109312332B CN201780034953.1A CN201780034953A CN109312332B CN 109312332 B CN109312332 B CN 109312332B CN 201780034953 A CN201780034953 A CN 201780034953A CN 109312332 B CN109312332 B CN 109312332B
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fetal
dna
cells
extravillous trophoblast
maternal
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CN109312332A (zh
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S·德鲁罗
D·R·阿尔曼特
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Wayne State University
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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    • G01—MEASURING; TESTING
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

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CN201780034953.1A 2016-04-06 2017-04-06 自子宫颈内管获取的绒毛外滋养层细胞的胎儿dna的分离与分析 Active CN109312332B (zh)

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US201662318982P 2016-04-06 2016-04-06
US62/318,982 2016-04-06
PCT/US2017/026335 WO2017176985A1 (en) 2016-04-06 2017-04-06 Isolation and analysis of fetal dna from extravillous trophoblast cells retrieved from the endocervical canal

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CN109312332A CN109312332A (zh) 2019-02-05
CN109312332B true CN109312332B (zh) 2022-07-08

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US (1) US10808239B2 (https=)
EP (1) EP3440209A4 (https=)
JP (2) JP7026098B2 (https=)
CN (1) CN109312332B (https=)
AU (1) AU2017246480B2 (https=)
WO (1) WO2017176985A1 (https=)

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WO2017180909A1 (en) 2016-04-13 2017-10-19 Nextgen Jane, Inc. Sample collection and preservation devices, systems and methods
AU2018355575A1 (en) 2017-10-27 2020-05-21 Juno Diagnostics, Inc. Devices, systems and methods for ultra-low volume liquid biopsy
AU2019205809A1 (en) * 2018-01-08 2020-08-13 Cradle Genomics, Inc. Methods and kits for nucleic acid isolation
US12462935B2 (en) 2018-03-30 2025-11-04 Nucleix Ltd. Deep learning-based methods, devices, and systems for prenatal testing
EP3730627A1 (en) * 2019-04-25 2020-10-28 Kiadis Pharma Intellectual Property BV Method for donor identity verification
CN112980779B (zh) * 2021-05-20 2021-08-24 广州凯普医药科技有限公司 一种从孕妇宫颈脱落细胞中分离胎盘滋养层细胞的方法
CN113234163B (zh) * 2021-07-13 2021-11-02 北京贝瑞和康生物技术有限公司 分离胎儿滋养层细胞的方法及试剂盒
CN116103388B (zh) * 2022-12-23 2024-01-23 北京大学第三医院（北京大学第三临床医学院） 一种用于着床前胚胎atxn3基因检测的试剂盒、系统和方法
KR102894686B1 (ko) 2023-05-08 2025-12-03 인제대학교 산학협력단 융모막 검사용 자동 검체 채취 장치
CN116445590A (zh) * 2023-05-24 2023-07-18 浙江大学医学院附属第一医院 一种基于he染色进行妊娠物基因分型的方法
CN117174273B (zh) * 2023-11-01 2024-02-23 南京金域医学检验所有限公司 一种用于肾穿刺活检的免疫荧光数据处理方法

Family Cites Families (13)

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Publication number Priority date Publication date Assignee Title
US5629147A (en) 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
EP0587951B1 (en) 1992-09-18 1997-12-17 AMERSHAM INTERNATIONAL plc Cell nuclei capture method and device used therefor
WO1999041613A1 (en) 1998-02-12 1999-08-19 Immunivest Methods and reagents for the rapid and efficient isolation of circulating cancer cells
AUPR749901A0 (en) 2001-09-06 2001-09-27 Monash University Method of identifying chromosomal abnormalities and prenatal diagnosis
US20050181429A1 (en) 2003-04-03 2005-08-18 Monaliza Medical Ltd. Non-invasive prenatal genetic diagnosis using transcervical cells
US20040197832A1 (en) 2003-04-03 2004-10-07 Mor Research Applications Ltd. Non-invasive prenatal genetic diagnosis using transcervical cells
DK2299275T3 (en) 2004-07-30 2018-05-07 Adeza Biomedical Corp Classification of oncofetal fetronectin level for pregnancy-related indications
US20070224597A1 (en) * 2006-03-23 2007-09-27 Biocept, Inc. Isolating fetal trophoblasts
US20090286271A1 (en) 2006-05-31 2009-11-19 Karumanchi Ananth S Methods of Diagnosing and Treating Complications of Pregnancy
CA2713545A1 (en) * 2008-01-30 2009-08-06 Novartis Ag Two stage enrichment of cell-free fetal dna in maternal plasma
WO2009103110A1 (en) 2008-02-18 2009-08-27 Genetic Technologies Limited Cell processing and/or enrichment methods
US9447467B2 (en) * 2009-04-21 2016-09-20 Genetic Technologies Limited Methods for obtaining fetal genetic material
CA2888746C (en) * 2012-10-19 2022-07-26 Wayne State University Identification and analysis of fetal trophoblast cells in cervical mucus for prenatal diagnosis

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CA3019953A1 (en) 2017-10-12
WO2017176985A8 (en) 2018-11-15
US20190153431A1 (en) 2019-05-23
AU2017246480B2 (en) 2023-06-01
AU2017246480A8 (en) 2018-12-06
JP7026098B2 (ja) 2022-02-25
WO2017176985A1 (en) 2017-10-12
CN109312332A (zh) 2019-02-05
EP3440209A1 (en) 2019-02-13
US10808239B2 (en) 2020-10-20
JP2019516398A (ja) 2019-06-20
AU2017246480A1 (en) 2018-10-25
EP3440209A4 (en) 2019-11-27
JP2022028827A (ja) 2022-02-16

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