JP2019516398A5 - - Google Patents
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- Publication number
- JP2019516398A5 JP2019516398A5 JP2019503634A JP2019503634A JP2019516398A5 JP 2019516398 A5 JP2019516398 A5 JP 2019516398A5 JP 2019503634 A JP2019503634 A JP 2019503634A JP 2019503634 A JP2019503634 A JP 2019503634A JP 2019516398 A5 JP2019516398 A5 JP 2019516398A5
- Authority
- JP
- Japan
- Prior art keywords
- fetal
- trophoblast cells
- extravillous trophoblast
- isolated
- dnase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000001605 fetal effect Effects 0.000 claims 52
- 210000002993 trophoblast Anatomy 0.000 claims 27
- 108020004414 DNA Proteins 0.000 claims 25
- 238000000034 method Methods 0.000 claims 23
- 230000008774 maternal effect Effects 0.000 claims 17
- 102000016911 Deoxyribonucleases Human genes 0.000 claims 14
- 108010053770 Deoxyribonucleases Proteins 0.000 claims 14
- 230000002934 lysing effect Effects 0.000 claims 8
- 238000012163 sequencing technique Methods 0.000 claims 7
- 210000004027 cell Anatomy 0.000 claims 5
- 230000035935 pregnancy Effects 0.000 claims 4
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 238000004458 analytical method Methods 0.000 claims 2
- 238000003556 assay Methods 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000005251 capillar electrophoresis Methods 0.000 claims 1
- 210000003754 fetus Anatomy 0.000 claims 1
- 235000019689 luncheon sausage Nutrition 0.000 claims 1
- 238000004949 mass spectrometry Methods 0.000 claims 1
- 238000011880 melting curve analysis Methods 0.000 claims 1
- 230000011987 methylation Effects 0.000 claims 1
- 238000007069 methylation reaction Methods 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 238000012175 pyrosequencing Methods 0.000 claims 1
- 238000007894 restriction fragment length polymorphism technique Methods 0.000 claims 1
- 239000004065 semiconductor Substances 0.000 claims 1
- 238000007841 sequencing by ligation Methods 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021187537A JP2022028827A (ja) | 2016-04-06 | 2021-11-18 | 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662318982P | 2016-04-06 | 2016-04-06 | |
| US62/318,982 | 2016-04-06 | ||
| PCT/US2017/026335 WO2017176985A1 (en) | 2016-04-06 | 2017-04-06 | Isolation and analysis of fetal dna from extravillous trophoblast cells retrieved from the endocervical canal |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021187537A Division JP2022028827A (ja) | 2016-04-06 | 2021-11-18 | 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019516398A JP2019516398A (ja) | 2019-06-20 |
| JP2019516398A5 true JP2019516398A5 (https=) | 2020-07-27 |
| JP7026098B2 JP7026098B2 (ja) | 2022-02-25 |
Family
ID=60001444
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019503634A Active JP7026098B2 (ja) | 2016-04-06 | 2017-04-06 | 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析 |
| JP2021187537A Withdrawn JP2022028827A (ja) | 2016-04-06 | 2021-11-18 | 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021187537A Withdrawn JP2022028827A (ja) | 2016-04-06 | 2021-11-18 | 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10808239B2 (https=) |
| EP (1) | EP3440209A4 (https=) |
| JP (2) | JP7026098B2 (https=) |
| CN (1) | CN109312332B (https=) |
| AU (1) | AU2017246480B2 (https=) |
| WO (1) | WO2017176985A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017180909A1 (en) | 2016-04-13 | 2017-10-19 | Nextgen Jane, Inc. | Sample collection and preservation devices, systems and methods |
| CN111526793A (zh) | 2017-10-27 | 2020-08-11 | 朱诺诊断学公司 | 用于超低体积液体活检的设备、系统和方法 |
| US20210062183A1 (en) * | 2018-01-08 | 2021-03-04 | Cradle Genomics, Inc. | Methods and kits for nucleic acid isolation |
| US12462935B2 (en) | 2018-03-30 | 2025-11-04 | Nucleix Ltd. | Deep learning-based methods, devices, and systems for prenatal testing |
| EP3730627A1 (en) * | 2019-04-25 | 2020-10-28 | Kiadis Pharma Intellectual Property BV | Method for donor identity verification |
| CN112980779B (zh) * | 2021-05-20 | 2021-08-24 | 广州凯普医药科技有限公司 | 一种从孕妇宫颈脱落细胞中分离胎盘滋养层细胞的方法 |
| CN113234163B (zh) * | 2021-07-13 | 2021-11-02 | 北京贝瑞和康生物技术有限公司 | 分离胎儿滋养层细胞的方法及试剂盒 |
| CN116103388B (zh) * | 2022-12-23 | 2024-01-23 | 北京大学第三医院（北京大学第三临床医学院） | 一种用于着床前胚胎atxn3基因检测的试剂盒、系统和方法 |
| KR102894686B1 (ko) | 2023-05-08 | 2025-12-03 | 인제대학교 산학협력단 | 융모막 검사용 자동 검체 채취 장치 |
| CN116445590A (zh) * | 2023-05-24 | 2023-07-18 | 浙江大学医学院附属第一医院 | 一种基于he染色进行妊娠物基因分型的方法 |
| CN117174273B (zh) * | 2023-11-01 | 2024-02-23 | 南京金域医学检验所有限公司 | 一种用于肾穿刺活检的免疫荧光数据处理方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5629147A (en) | 1992-07-17 | 1997-05-13 | Aprogenex, Inc. | Enriching and identifying fetal cells in maternal blood for in situ hybridization |
| DE69223617T2 (de) * | 1992-09-18 | 1998-04-09 | Amersham Int Plc | Verfahren zum Auffangen von Zellkernen und dafür verwendete Vorrichtung |
| BR9907852A (pt) | 1998-02-12 | 2000-10-24 | Immunivest Corp | Processos para detectar e enumerar células raras e cancerosas em uma população celular mista, para diagnosticar câncer de estágio precoce em um paciente de teste, para determinar a probabilidade de recorrência de câncer em um paciente humano anteriormente tratado de câncer, para distinguir um carcinoma confinado ao órgão de um carcinoma com propriedades metastáticas, para acompanhar a situação de remissão em um paciente humano com câncer que passa pelo tratamento de terapia contra o câncer e para aumentar quantidades de células epiteliais circulantes em uma amostra de sangue, partìcula magnética revestida, composição, conjuntos de teste para avaliar uma amostra de paciente quanto a presença de células raras circulantes, quanto a presença de células de tumor circulantes, quanto a presença de células de câncer de mama circulantes, quanto a presença de células de câncer de próstata circulantes, quanto a presença de células de câncer de cólon circulantes, quanto a presença de células de câncer de bexiga circulantes e para monitorar um paciente quanto a recorrência de câncer, e, fração de sangue periférico enriquecido quanto a células neoplásticas circulantes |
| AUPR749901A0 (en) | 2001-09-06 | 2001-09-27 | Monash University | Method of identifying chromosomal abnormalities and prenatal diagnosis |
| US20040197832A1 (en) | 2003-04-03 | 2004-10-07 | Mor Research Applications Ltd. | Non-invasive prenatal genetic diagnosis using transcervical cells |
| US20050181429A1 (en) | 2003-04-03 | 2005-08-18 | Monaliza Medical Ltd. | Non-invasive prenatal genetic diagnosis using transcervical cells |
| JP2008514900A (ja) | 2004-07-30 | 2008-05-08 | アデザ・バイオメデイカル・コーポレイシヨン | 疾病および他の状態のマーカーとしての癌胎児性フィブロネクチンならびに癌胎児性フィブロネクチンの検出のための方法 |
| US20070224597A1 (en) * | 2006-03-23 | 2007-09-27 | Biocept, Inc. | Isolating fetal trophoblasts |
| US20090286271A1 (en) | 2006-05-31 | 2009-11-19 | Karumanchi Ananth S | Methods of Diagnosing and Treating Complications of Pregnancy |
| US20110183338A1 (en) * | 2008-01-30 | 2011-07-28 | Novartis Vaccines And Diagnostics, Inc. | Two stage enrichment of cell-free fetal dna in maternal plasma |
| CA2752838A1 (en) | 2008-02-18 | 2009-08-27 | Genetic Technologies Limited | Cell processing and/or enrichment methods |
| WO2010121294A1 (en) * | 2009-04-21 | 2010-10-28 | Genetic Technologies Limited | Methods for obtaining fetal genetic material |
| CA2888746C (en) * | 2012-10-19 | 2022-07-26 | Wayne State University | Identification and analysis of fetal trophoblast cells in cervical mucus for prenatal diagnosis |
-
2017
- 2017-04-06 US US16/091,413 patent/US10808239B2/en active Active
- 2017-04-06 AU AU2017246480A patent/AU2017246480B2/en active Active
- 2017-04-06 JP JP2019503634A patent/JP7026098B2/ja active Active
- 2017-04-06 EP EP17779814.7A patent/EP3440209A4/en active Pending
- 2017-04-06 WO PCT/US2017/026335 patent/WO2017176985A1/en not_active Ceased
- 2017-04-06 CN CN201780034953.1A patent/CN109312332B/zh active Active
-
2021
- 2021-11-18 JP JP2021187537A patent/JP2022028827A/ja not_active Withdrawn
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