JP2019516398A5 - - Google Patents
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- Publication number
- JP2019516398A5 JP2019516398A5 JP2019503634A JP2019503634A JP2019516398A5 JP 2019516398 A5 JP2019516398 A5 JP 2019516398A5 JP 2019503634 A JP2019503634 A JP 2019503634A JP 2019503634 A JP2019503634 A JP 2019503634A JP 2019516398 A5 JP2019516398 A5 JP 2019516398A5
- Authority
- JP
- Japan
- Prior art keywords
- fetal
- trophoblast cells
- extravillous trophoblast
- isolated
- dnase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000001605 fetal effect Effects 0.000 claims 52
- 210000002993 trophoblast Anatomy 0.000 claims 27
- 108020004414 DNA Proteins 0.000 claims 25
- 238000000034 method Methods 0.000 claims 23
- 230000008774 maternal effect Effects 0.000 claims 17
- 102000016911 Deoxyribonucleases Human genes 0.000 claims 14
- 108010053770 Deoxyribonucleases Proteins 0.000 claims 14
- 230000002934 lysing effect Effects 0.000 claims 8
- 238000012163 sequencing technique Methods 0.000 claims 7
- 210000004027 cell Anatomy 0.000 claims 5
- 230000035935 pregnancy Effects 0.000 claims 4
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 238000004458 analytical method Methods 0.000 claims 2
- 238000003556 assay Methods 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000005251 capillar electrophoresis Methods 0.000 claims 1
- 210000003754 fetus Anatomy 0.000 claims 1
- 235000019689 luncheon sausage Nutrition 0.000 claims 1
- 238000004949 mass spectrometry Methods 0.000 claims 1
- 238000011880 melting curve analysis Methods 0.000 claims 1
- 230000011987 methylation Effects 0.000 claims 1
- 238000007069 methylation reaction Methods 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 238000012175 pyrosequencing Methods 0.000 claims 1
- 238000007894 restriction fragment length polymorphism technique Methods 0.000 claims 1
- 239000004065 semiconductor Substances 0.000 claims 1
- 238000007841 sequencing by ligation Methods 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021187537A JP2022028827A (ja) | 2016-04-06 | 2021-11-18 | 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662318982P | 2016-04-06 | 2016-04-06 | |
| US62/318,982 | 2016-04-06 | ||
| PCT/US2017/026335 WO2017176985A1 (en) | 2016-04-06 | 2017-04-06 | Isolation and analysis of fetal dna from extravillous trophoblast cells retrieved from the endocervical canal |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021187537A Division JP2022028827A (ja) | 2016-04-06 | 2021-11-18 | 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019516398A JP2019516398A (ja) | 2019-06-20 |
| JP2019516398A5 true JP2019516398A5 (https=) | 2020-07-27 |
| JP7026098B2 JP7026098B2 (ja) | 2022-02-25 |
Family
ID=60001444
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019503634A Active JP7026098B2 (ja) | 2016-04-06 | 2017-04-06 | 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析 |
| JP2021187537A Withdrawn JP2022028827A (ja) | 2016-04-06 | 2021-11-18 | 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021187537A Withdrawn JP2022028827A (ja) | 2016-04-06 | 2021-11-18 | 子宮頸管より採取された絨毛外栄養膜細胞からの胎児ｄｎａの単離と分析 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10808239B2 (https=) |
| EP (1) | EP3440209A4 (https=) |
| JP (2) | JP7026098B2 (https=) |
| CN (1) | CN109312332B (https=) |
| AU (1) | AU2017246480B2 (https=) |
| WO (1) | WO2017176985A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017180909A1 (en) | 2016-04-13 | 2017-10-19 | Nextgen Jane, Inc. | Sample collection and preservation devices, systems and methods |
| AU2018355575A1 (en) | 2017-10-27 | 2020-05-21 | Juno Diagnostics, Inc. | Devices, systems and methods for ultra-low volume liquid biopsy |
| AU2019205809A1 (en) * | 2018-01-08 | 2020-08-13 | Cradle Genomics, Inc. | Methods and kits for nucleic acid isolation |
| US12462935B2 (en) | 2018-03-30 | 2025-11-04 | Nucleix Ltd. | Deep learning-based methods, devices, and systems for prenatal testing |
| EP3730627A1 (en) * | 2019-04-25 | 2020-10-28 | Kiadis Pharma Intellectual Property BV | Method for donor identity verification |
| CN112980779B (zh) * | 2021-05-20 | 2021-08-24 | 广州凯普医药科技有限公司 | 一种从孕妇宫颈脱落细胞中分离胎盘滋养层细胞的方法 |
| CN113234163B (zh) * | 2021-07-13 | 2021-11-02 | 北京贝瑞和康生物技术有限公司 | 分离胎儿滋养层细胞的方法及试剂盒 |
| CN116103388B (zh) * | 2022-12-23 | 2024-01-23 | 北京大学第三医院（北京大学第三临床医学院） | 一种用于着床前胚胎atxn3基因检测的试剂盒、系统和方法 |
| KR102894686B1 (ko) | 2023-05-08 | 2025-12-03 | 인제대학교 산학협력단 | 융모막 검사용 자동 검체 채취 장치 |
| CN116445590A (zh) * | 2023-05-24 | 2023-07-18 | 浙江大学医学院附属第一医院 | 一种基于he染色进行妊娠物基因分型的方法 |
| CN117174273B (zh) * | 2023-11-01 | 2024-02-23 | 南京金域医学检验所有限公司 | 一种用于肾穿刺活检的免疫荧光数据处理方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5629147A (en) | 1992-07-17 | 1997-05-13 | Aprogenex, Inc. | Enriching and identifying fetal cells in maternal blood for in situ hybridization |
| EP0587951B1 (en) | 1992-09-18 | 1997-12-17 | AMERSHAM INTERNATIONAL plc | Cell nuclei capture method and device used therefor |
| WO1999041613A1 (en) | 1998-02-12 | 1999-08-19 | Immunivest | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
| AUPR749901A0 (en) | 2001-09-06 | 2001-09-27 | Monash University | Method of identifying chromosomal abnormalities and prenatal diagnosis |
| US20050181429A1 (en) | 2003-04-03 | 2005-08-18 | Monaliza Medical Ltd. | Non-invasive prenatal genetic diagnosis using transcervical cells |
| US20040197832A1 (en) | 2003-04-03 | 2004-10-07 | Mor Research Applications Ltd. | Non-invasive prenatal genetic diagnosis using transcervical cells |
| DK2299275T3 (en) | 2004-07-30 | 2018-05-07 | Adeza Biomedical Corp | Classification of oncofetal fetronectin level for pregnancy-related indications |
| US20070224597A1 (en) * | 2006-03-23 | 2007-09-27 | Biocept, Inc. | Isolating fetal trophoblasts |
| US20090286271A1 (en) | 2006-05-31 | 2009-11-19 | Karumanchi Ananth S | Methods of Diagnosing and Treating Complications of Pregnancy |
| CA2713545A1 (en) * | 2008-01-30 | 2009-08-06 | Novartis Ag | Two stage enrichment of cell-free fetal dna in maternal plasma |
| WO2009103110A1 (en) | 2008-02-18 | 2009-08-27 | Genetic Technologies Limited | Cell processing and/or enrichment methods |
| US9447467B2 (en) * | 2009-04-21 | 2016-09-20 | Genetic Technologies Limited | Methods for obtaining fetal genetic material |
| CA2888746C (en) * | 2012-10-19 | 2022-07-26 | Wayne State University | Identification and analysis of fetal trophoblast cells in cervical mucus for prenatal diagnosis |
-
2017
- 2017-04-06 WO PCT/US2017/026335 patent/WO2017176985A1/en not_active Ceased
- 2017-04-06 JP JP2019503634A patent/JP7026098B2/ja active Active
- 2017-04-06 AU AU2017246480A patent/AU2017246480B2/en active Active
- 2017-04-06 US US16/091,413 patent/US10808239B2/en active Active
- 2017-04-06 EP EP17779814.7A patent/EP3440209A4/en active Pending
- 2017-04-06 CN CN201780034953.1A patent/CN109312332B/zh active Active
-
2021
- 2021-11-18 JP JP2021187537A patent/JP2022028827A/ja not_active Withdrawn
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