JP7021182B2 - 足場材料、方法および使用 - Google Patents

足場材料、方法および使用 Download PDF

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Publication number
JP7021182B2
JP7021182B2 JP2019501766A JP2019501766A JP7021182B2 JP 7021182 B2 JP7021182 B2 JP 7021182B2 JP 2019501766 A JP2019501766 A JP 2019501766A JP 2019501766 A JP2019501766 A JP 2019501766A JP 7021182 B2 JP7021182 B2 JP 7021182B2
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Japan
Prior art keywords
polymer
scaffold
particles
carrier
plasticizer
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JP2019501766A
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English (en)
Japanese (ja)
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JP2019516524A5 (https=
JP2019516524A (ja
Inventor
レオナルディ，アントニオ
シー． コックス，ヘレン
キャリー，シオバン
マシューズ，チャールズ
ロマス，アレキサンダー
エム シェイクシェフ，ケビン
エー カーク，ロビン
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Locate Bio Ltd
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Locate Bio Ltd
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Priority claimed from GBGB1605122.9A external-priority patent/GB201605122D0/en
Application filed by Locate Bio Ltd filed Critical Locate Bio Ltd
Publication of JP2019516524A publication Critical patent/JP2019516524A/ja
Publication of JP2019516524A5 publication Critical patent/JP2019516524A5/ja
Priority to JP2022015471A priority Critical patent/JP2022068212A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/10—Ceramics or glasses
    • A61L27/105—Ceramics or glasses containing Al2O3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/502—Plasticizers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Ceramic Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
JP2019501766A 2016-03-24 2017-03-23 足場材料、方法および使用 Active JP7021182B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022015471A JP2022068212A (ja) 2016-03-24 2022-02-03 足場材料、方法および使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB1605122.9A GB201605122D0 (en) 2016-03-24 2016-03-24 Scaffolding material, methods and uses
GB1605122.9 2016-03-24
GB201606395 2016-04-13
GB1606395.0 2016-04-13
PCT/GB2017/050815 WO2017163072A1 (en) 2016-03-24 2017-03-23 Scaffolding material, methods and uses

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022015471A Division JP2022068212A (ja) 2016-03-24 2022-02-03 足場材料、方法および使用

Publications (3)

Publication Number Publication Date
JP2019516524A JP2019516524A (ja) 2019-06-20
JP2019516524A5 JP2019516524A5 (https=) 2020-04-30
JP7021182B2 true JP7021182B2 (ja) 2022-02-16

Family

ID=58464594

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019501766A Active JP7021182B2 (ja) 2016-03-24 2017-03-23 足場材料、方法および使用
JP2022015471A Pending JP2022068212A (ja) 2016-03-24 2022-02-03 足場材料、方法および使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022015471A Pending JP2022068212A (ja) 2016-03-24 2022-02-03 足場材料、方法および使用

Country Status (8)

Country Link
US (2) US20200093956A1 (https=)
EP (1) EP3432939B1 (https=)
JP (2) JP7021182B2 (https=)
KR (1) KR20190003945A (https=)
CN (1) CN109475662A (https=)
AU (1) AU2017236423A1 (https=)
CA (1) CA3018629A1 (https=)
WO (1) WO2017163072A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110564123B (zh) * 2019-10-29 2021-07-20 吉林大学 一种聚乳酸/生物玻璃复合材料及制备方法
KR102266384B1 (ko) * 2021-01-25 2021-06-21 주식회사 울트라브이 필러용 생분해성 고분자 미세입자, 이를 포함한 필러용 동결건조체, 그 제조방법 및 상기 동결건조체를 포함하는 필러용 주사제
GB202306382D0 (en) 2023-04-28 2023-06-14 Locate Bio Ltd Osteoinstructive calcium phosphate ceramic material

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015019109A1 (en) 2013-08-09 2015-02-12 Locate Therapeutics Limited Composition and delivery system

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US3107573A (en) * 1960-10-28 1963-10-22 Standard Oil Co Method of restricting a solid propellant
IT1268621B1 (it) * 1994-10-07 1997-03-06 P & G Spa Composizione adesiva e relativo procedimento di preparazione.
JP3503045B2 (ja) * 1997-05-13 2004-03-02 タキロン株式会社 形状記憶生体内分解吸収性材料
CA2285149A1 (en) * 1998-10-07 2000-04-07 Isotis B.V. Device for tissue engineering a bone equivalent
ATE419834T1 (de) * 2000-11-20 2009-01-15 Elan Pharma Int Ltd Nanopartikel bestehend aus einem arzneistoff und copolymeren von vinyl pyrrolidon und vinyl acetat als oberflächenstabilisatoren
JP4669662B2 (ja) * 2001-10-25 2011-04-13 ユニヴァーシティー オブ コネティカット 生物活性材料、生物活性材料の製法およびその使用方法
GB0307011D0 (en) 2003-03-27 2003-04-30 Regentec Ltd Porous matrix
US8163030B2 (en) * 2004-05-06 2012-04-24 Degradable Solutions Ag Biocompatible bone implant compositions and methods for repairing a bone defect
US8053000B2 (en) * 2005-06-07 2011-11-08 Dr. Reddy's Laboratories Limited Compositions for drug delivery
JP2007236802A (ja) * 2006-03-10 2007-09-20 Takiron Co Ltd インプラント傾斜材料
EP1872807A1 (en) * 2006-06-30 2008-01-02 Scil Technology GmbH Biomaterial containing degradation stabilized polymer
RU2454220C2 (ru) * 2006-08-16 2012-06-27 Новартис Аг Способ получения твердых дисперсий высококристаллических терапевтических соединений
GB0701896D0 (en) * 2007-02-01 2007-03-14 Regentec Ltd Composition
US8288344B2 (en) * 2007-03-15 2012-10-16 Musculoskeletal Transplant Foundation Ceramic composition for filling bone defects
EP2207577B1 (en) * 2007-10-26 2015-01-14 National Institute Of Immunology Biodegradable polymer scaffold and process for preparation thereof
GB0903810D0 (en) * 2009-03-05 2009-04-22 Regentec Ltd Delivery system
AU2010275697B2 (en) * 2009-07-23 2014-01-30 Progentix Orthobiology B.V. Injectable and moldable osteoinductive ceramic materials
AU2011329054B2 (en) * 2010-11-15 2015-05-28 Zimmer Orthobiologics, Inc. Bone void fillers
GB201317005D0 (en) * 2013-09-25 2013-11-06 Blueberry Therapeutics Ltd Composition and methods of treatment
JP6460540B2 (ja) * 2014-04-08 2019-01-30 ディーエスエム アイピー アセッツ ビー．ブイ．Ｄｓｍ Ｉｐ Ａｓｓｅｔｓ Ｂ．Ｖ． 関節障害の処置のために使用される生分解性ポリエステルアミド

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2015019109A1 (en) 2013-08-09 2015-02-12 Locate Therapeutics Limited Composition and delivery system

Also Published As

Publication number Publication date
CN109475662A (zh) 2019-03-15
EP3432939A1 (en) 2019-01-30
KR20190003945A (ko) 2019-01-10
WO2017163072A1 (en) 2017-09-28
JP2022068212A (ja) 2022-05-09
JP2019516524A (ja) 2019-06-20
AU2017236423A1 (en) 2018-11-15
US20200093956A1 (en) 2020-03-26
CA3018629A1 (en) 2017-09-28
EP3432939B1 (en) 2024-05-01
US20210290818A1 (en) 2021-09-23

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