JP7016110B2 - スティル病と敗血症との鑑別用バイオマーカー - Google Patents

スティル病と敗血症との鑑別用バイオマーカー Download PDF

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Publication number
JP7016110B2
JP7016110B2 JP2018083489A JP2018083489A JP7016110B2 JP 7016110 B2 JP7016110 B2 JP 7016110B2 JP 2018083489 A JP2018083489 A JP 2018083489A JP 2018083489 A JP2018083489 A JP 2018083489A JP 7016110 B2 JP7016110 B2 JP 7016110B2
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Prior art keywords
nucleic acid
protein
csf
transcript
biomarker
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JP2018083489A
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Japanese (ja)
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JP2019190976A (ja
Inventor
智裕 古賀
純 川上
俊太朗 佐藤
清志 右田
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Nagasaki University
Fukushima Medical University
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Nagasaki University
Fukushima Medical University
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Priority to JP2018083489A priority Critical patent/JP7016110B2/ja
Priority to PCT/JP2019/017149 priority patent/WO2019208542A1/fr
Publication of JP2019190976A publication Critical patent/JP2019190976A/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP2018083489A 2018-04-24 2018-04-24 スティル病と敗血症との鑑別用バイオマーカー Active JP7016110B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2018083489A JP7016110B2 (ja) 2018-04-24 2018-04-24 スティル病と敗血症との鑑別用バイオマーカー
PCT/JP2019/017149 WO2019208542A1 (fr) 2018-04-24 2019-04-23 Biomarqueur permettant de différencier la maladie de still et la septicémie

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2018083489A JP7016110B2 (ja) 2018-04-24 2018-04-24 スティル病と敗血症との鑑別用バイオマーカー

Publications (2)

Publication Number Publication Date
JP2019190976A JP2019190976A (ja) 2019-10-31
JP7016110B2 true JP7016110B2 (ja) 2022-02-21

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ID=68294044

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JP2018083489A Active JP7016110B2 (ja) 2018-04-24 2018-04-24 スティル病と敗血症との鑑別用バイオマーカー

Country Status (2)

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JP (1) JP7016110B2 (fr)
WO (1) WO2019208542A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116888476A (zh) * 2021-02-15 2023-10-13 佳能医疗系统株式会社 成人斯蒂尔病的检查方法及检查试剂盒

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
PRIORI Roberta et al.，Interleukin 18: A biomarker for differential diagnosis between adult-onset Still's disease and sepsi，Journal of Rheumatology，2014年06月，Vol.41,No.6，PP.1118-1123
RAU Monica et al.，Clinical Manifestations but not Cytokine Profiles Differentiate Adult-onset Still's Disease and Seps，Journal of Rheumatology，2010年11月，Vol.37, No.11，pp.2369-2376.
大田明英ほか，成人Still病患者血清中のサイトカイン濃度の検討，自己免疫疾患調査研究班 平成6年度研究報告書，1995年，PP.121-123

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WO2019208542A1 (fr) 2019-10-31
JP2019190976A (ja) 2019-10-31

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