JP6990667B2 - 眼性新血管形成を低減するための組成物および方法 - Google Patents

眼性新血管形成を低減するための組成物および方法 Download PDF

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JP6990667B2
JP6990667B2 JP2018565844A JP2018565844A JP6990667B2 JP 6990667 B2 JP6990667 B2 JP 6990667B2 JP 2018565844 A JP2018565844 A JP 2018565844A JP 2018565844 A JP2018565844 A JP 2018565844A JP 6990667 B2 JP6990667 B2 JP 6990667B2
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ranibizumab
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JP2019521989A5 (enExample
JP2019521989A (ja
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マーク ブルーメンクランツ,
メヒディ ガスミ,
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アドヴェラム バイオテクノロジーズ, インコーポレイテッド
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    • AHUMAN NECESSITIES
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    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
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    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N2750/14011Parvoviridae
    • C12N2750/14111Dependovirus, e.g. adenoassociated viruses
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JP2018565844A 2016-06-16 2017-06-16 眼性新血管形成を低減するための組成物および方法 Active JP6990667B2 (ja)

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JP2021197648A JP7384447B2 (ja) 2016-06-16 2021-12-06 眼性新血管形成を低減するための組成物および方法
JP2023173614A JP7606245B2 (ja) 2016-06-16 2023-10-05 眼性新血管形成を低減するための組成物および方法
JP2024213242A JP2025038012A (ja) 2016-06-16 2024-12-06 眼性新血管形成を低減するための組成物および方法

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US201662351231P 2016-06-16 2016-06-16
US62/351,231 2016-06-16
PCT/US2017/038012 WO2017218981A2 (en) 2016-06-16 2017-06-16 Compositions and methods for reducing ocular neovascularization

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JP2023173614A Active JP7606245B2 (ja) 2016-06-16 2023-10-05 眼性新血管形成を低減するための組成物および方法
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US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
KR20170137730A (ko) 2015-03-02 2017-12-13 애드베룸 바이오테크놀로지스, 인코포레이티드 망막 추상체에 폴리뉴클레오타이드의 유리체 내 전달을 위한 조성물 및 방법
WO2017117464A1 (en) 2015-12-30 2017-07-06 Kodiak Sciences Inc. Antibodies and conjugates thereof
US11192925B2 (en) 2016-10-19 2021-12-07 Adverum Biotechnologies, Inc. Modified AAV capsids and uses thereof
EP4653536A2 (en) 2017-03-17 2025-11-26 Adverum Biotechnologies, Inc. Compositions and methods for enhanced gene expression
JP2021506861A (ja) 2017-12-19 2021-02-22 アコーオス インコーポレイテッド 内耳への治療用抗体のaav媒介送達
BR112020017872A2 (pt) 2018-03-02 2020-12-22 Kodiak Sciences Inc. Anticorpos de il-6 e construtos de fusão e conjugados dos mesmos
EP3789489A4 (en) * 2018-03-30 2022-01-05 Tomoki Todo ANTI-SWEEPER TYPE ONCOLYTIC VIRUS
BR112021021156A2 (pt) * 2019-04-24 2022-02-08 Regenxbio Inc Terapêuticos anticorpos totalmente humanos pós-tradução modificados
WO2021046245A1 (en) * 2019-09-04 2021-03-11 University Of Massachusetts Adeno-associated virus vector platform for delivery of kh902 (conbercept) and uses thereof
MX2022002960A (es) * 2019-09-11 2022-04-06 Adverum Biotechnologies Inc Metodos para tratar enfermedades neovasculares oculares usando variantes de aav2 que codifican para aflibercept.
WO2021050094A1 (en) * 2019-09-11 2021-03-18 Adverum Biotechnologies, Inc. Methods of treating ocular neovascular diseases using aav2 variants encoding aflibercept
CN114728049A (zh) * 2019-10-07 2022-07-08 再生生物股份有限公司 腺相关病毒载体药物组合物和方法
WO2021072265A1 (en) 2019-10-10 2021-04-15 Kodiak Sciences Inc. Methods of treating an eye disorder
US20230057380A1 (en) * 2019-11-26 2023-02-23 University Of Massachusetts Recombinant adeno-associated virus for delivery of kh902 (conbercept) and uses thereof
WO2021163451A1 (en) * 2020-02-14 2021-08-19 Asklepios Biopharmaceutical, Inc. Method of treating gene therapy associated toxicity with antibiotics
IL303317A (en) 2020-12-01 2023-07-01 Akouos Inc ANTI-NATURAL ANTIBODY STRUCTURES AND RELATED METHODS FOR THE TREATMENT OF SYMPTOMS ASSOCIATED WITH VESTIBULAR SWANNOMA
CN115869425B (zh) * 2022-12-12 2024-08-20 北京生物制品研究所有限责任公司 一种aav眼用注射液及其制备方法和应用

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RS63282B1 (sr) 2022-06-30
HRP20220612T1 (hr) 2022-07-22
HUE059424T2 (hu) 2022-11-28
ES2916344T3 (es) 2022-06-30
JP7384447B2 (ja) 2023-11-21
JP2023171953A (ja) 2023-12-05
WO2017218981A3 (en) 2018-02-15
AU2017286680B2 (en) 2023-01-19
EP4427808A2 (en) 2024-09-11
AU2023202277A1 (en) 2023-05-11
WO2017218981A2 (en) 2017-12-21
SI3472317T1 (sl) 2022-08-31
PT3472317T (pt) 2022-06-27
KR20190038536A (ko) 2019-04-08
EP4427808A3 (en) 2024-10-30
EP4083203C0 (en) 2024-08-07
CY1125152T1 (el) 2024-12-13
DK3472317T3 (da) 2022-05-23
JP7606245B2 (ja) 2024-12-25
JP2025038012A (ja) 2025-03-18
SG11201811230RA (en) 2019-01-30
AU2017286680A1 (en) 2019-01-31
EP3472317A4 (en) 2020-02-26
JP2019521989A (ja) 2019-08-08
EP4083203B1 (en) 2024-08-07
KR20220162881A (ko) 2022-12-08
SMT202200251T1 (it) 2022-07-21
EP3472317A2 (en) 2019-04-24
US20230322911A1 (en) 2023-10-12
KR102622823B1 (ko) 2024-01-10
JP2022028928A (ja) 2022-02-16
US20190100582A1 (en) 2019-04-04
EP3472317B1 (en) 2022-03-16
EP4083203A1 (en) 2022-11-02
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