JP6977029B2 - レット症候群を治療するためのプリドピジンの使用 - Google Patents
レット症候群を治療するためのプリドピジンの使用 Download PDFInfo
- Publication number
- JP6977029B2 JP6977029B2 JP2019514217A JP2019514217A JP6977029B2 JP 6977029 B2 JP6977029 B2 JP 6977029B2 JP 2019514217 A JP2019514217 A JP 2019514217A JP 2019514217 A JP2019514217 A JP 2019514217A JP 6977029 B2 JP6977029 B2 JP 6977029B2
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- JP
- Japan
- Prior art keywords
- predopidine
- subject
- use according
- administered
- mecp2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662395854P | 2016-09-16 | 2016-09-16 | |
| US62/395,854 | 2016-09-16 | ||
| PCT/US2017/051803 WO2018053280A1 (en) | 2016-09-16 | 2017-09-15 | Use of pridopidine for treating rett syndrome |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019532926A JP2019532926A (ja) | 2019-11-14 |
| JP2019532926A5 JP2019532926A5 (https=) | 2019-12-26 |
| JP6977029B2 true JP6977029B2 (ja) | 2021-12-08 |
Family
ID=61619744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019514217A Active JP6977029B2 (ja) | 2016-09-16 | 2017-09-15 | レット症候群を治療するためのプリドピジンの使用 |
Country Status (13)
| Country | Link |
|---|---|
| EP (2) | EP3512506B1 (https=) |
| JP (1) | JP6977029B2 (https=) |
| CN (1) | CN109982686A (https=) |
| AU (1) | AU2017326013B2 (https=) |
| BR (1) | BR112019005040A2 (https=) |
| CA (1) | CA3036984C (https=) |
| DK (2) | DK4005570T3 (https=) |
| ES (2) | ES2909557T3 (https=) |
| HU (1) | HUE058314T2 (https=) |
| IL (1) | IL265342B2 (https=) |
| MX (1) | MX388845B (https=) |
| PL (2) | PL3512506T3 (https=) |
| WO (1) | WO2018053280A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11090297B2 (en) | 2013-06-21 | 2021-08-17 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating huntington's disease |
| HK1221646A1 (zh) | 2013-06-21 | 2017-06-09 | Teva Pharmaceuticals International Gmbh | 高剂量普利多匹定用於治疗亨廷顿舞蹈症的用途 |
| CA3035099C (en) | 2016-08-24 | 2023-01-17 | Prilenia Therapeutics Development Ltd. | Use of pridopidine for treating dystonias |
| EP4516356A3 (en) | 2016-08-24 | 2025-05-14 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating functional decline |
| HUE058314T2 (hu) | 2016-09-16 | 2022-07-28 | Prilenia Neurotherapeutics Ltd | Pridopidin alkalmazása Rett-szindróma kezelésére |
| US12102627B2 (en) | 2016-09-16 | 2024-10-01 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating rett syndrome |
| US12036213B2 (en) | 2017-09-08 | 2024-07-16 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating drug induced dyskinesias |
| CN113395964A (zh) | 2019-02-04 | 2021-09-14 | 普瑞尼亚神经治疗有限公司 | 用于帕金森氏病和与帕金森症相关的其它疾病的低剂量普利多匹定 |
| CN116472043A (zh) * | 2020-10-20 | 2023-07-21 | 普瑞尼亚神经治疗有限公司 | 普利多匹定和类似物用于治疗焦虑和抑郁的用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9904724D0 (sv) * | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
| CA2584831C (en) | 2004-10-13 | 2013-09-17 | Neurosearch Sweden Ab | Process for the synthesis of 4-(3-methanesulfonylphenyl)-1-n-propyl-piperidine |
| JP2013536825A (ja) | 2010-09-03 | 2013-09-26 | イバックス・インターナショナル・ゲーエムベーハー | ドパミン作動性安定化剤として有用なプリドピジンの重水素化類似体 |
| TWI579272B (zh) * | 2011-12-08 | 2017-04-21 | 梯瓦製藥國際有限責任公司 | 普多比啶（ｐｒｉｄｏｐｉｄｉｎｅ）之氫溴酸鹽 |
| AU2013243461A1 (en) | 2012-04-04 | 2014-11-06 | Teva Pharmaceuticals International Gmbh | Pharmaceutical compositions for combination therapy |
| HK1221646A1 (zh) | 2013-06-21 | 2017-06-09 | Teva Pharmaceuticals International Gmbh | 高剂量普利多匹定用於治疗亨廷顿舞蹈症的用途 |
| MX377576B (es) * | 2014-01-22 | 2025-03-04 | Prilenia Neurotherapeutics Ltd | Formulaciones de pridopidina de liberación modificada. |
| WO2016138135A1 (en) * | 2015-02-25 | 2016-09-01 | Teva Pharmaceuticals International Gmbh | Sigma-1 receptor modulators for treating huntington's disease |
| JP6887952B2 (ja) * | 2015-02-25 | 2021-06-16 | プリレニア ニューロセラピューティクス リミテッド | 認知機能を改善するため、およびアルツハイマー病を治療するためのプリドピジンの使用 |
| HUE058314T2 (hu) | 2016-09-16 | 2022-07-28 | Prilenia Neurotherapeutics Ltd | Pridopidin alkalmazása Rett-szindróma kezelésére |
-
2017
- 2017-09-15 HU HUE17851614A patent/HUE058314T2/hu unknown
- 2017-09-15 PL PL17851614T patent/PL3512506T3/pl unknown
- 2017-09-15 DK DK22150695.9T patent/DK4005570T3/da active
- 2017-09-15 MX MX2019003069A patent/MX388845B/es unknown
- 2017-09-15 EP EP17851614.2A patent/EP3512506B1/en active Active
- 2017-09-15 DK DK17851614.2T patent/DK3512506T3/da active
- 2017-09-15 BR BR112019005040A patent/BR112019005040A2/pt not_active Application Discontinuation
- 2017-09-15 CN CN201780071045.XA patent/CN109982686A/zh active Pending
- 2017-09-15 ES ES17851614T patent/ES2909557T3/es active Active
- 2017-09-15 CA CA3036984A patent/CA3036984C/en active Active
- 2017-09-15 PL PL22150695.9T patent/PL4005570T3/pl unknown
- 2017-09-15 JP JP2019514217A patent/JP6977029B2/ja active Active
- 2017-09-15 WO PCT/US2017/051803 patent/WO2018053280A1/en not_active Ceased
- 2017-09-15 EP EP22150695.9A patent/EP4005570B1/en active Active
- 2017-09-15 AU AU2017326013A patent/AU2017326013B2/en active Active
- 2017-09-15 ES ES22150695T patent/ES2986807T3/es active Active
-
2019
- 2019-03-13 IL IL265342A patent/IL265342B2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA3036984A1 (en) | 2018-03-22 |
| EP4005570B1 (en) | 2024-05-15 |
| EP3512506A1 (en) | 2019-07-24 |
| BR112019005040A2 (pt) | 2019-07-16 |
| CA3036984C (en) | 2023-07-18 |
| MX388845B (es) | 2025-03-20 |
| PL3512506T3 (pl) | 2022-05-30 |
| DK4005570T3 (da) | 2024-08-19 |
| EP4005570A1 (en) | 2022-06-01 |
| IL265342A (en) | 2019-05-30 |
| IL265342B2 (en) | 2023-06-01 |
| HUE058314T2 (hu) | 2022-07-28 |
| AU2017326013A1 (en) | 2019-04-11 |
| JP2019532926A (ja) | 2019-11-14 |
| EP3512506A4 (en) | 2020-05-27 |
| ES2986807T3 (es) | 2024-11-12 |
| WO2018053280A1 (en) | 2018-03-22 |
| AU2017326013B2 (en) | 2020-12-24 |
| EP3512506B1 (en) | 2022-01-26 |
| CN109982686A (zh) | 2019-07-05 |
| MX2019003069A (es) | 2019-09-02 |
| DK3512506T3 (da) | 2022-04-19 |
| PL4005570T3 (pl) | 2024-09-23 |
| ES2909557T3 (es) | 2022-05-09 |
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