JP6971574B2 - 合成メッセンジャーrnaによるヒト人工多能性幹細胞のフィーダーフリー誘導 - Google Patents
合成メッセンジャーrnaによるヒト人工多能性幹細胞のフィーダーフリー誘導 Download PDFInfo
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- JP6971574B2 JP6971574B2 JP2016514171A JP2016514171A JP6971574B2 JP 6971574 B2 JP6971574 B2 JP 6971574B2 JP 2016514171 A JP2016514171 A JP 2016514171A JP 2016514171 A JP2016514171 A JP 2016514171A JP 6971574 B2 JP6971574 B2 JP 6971574B2
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- C12N15/09—Recombinant DNA-technology
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/605—Nanog
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/608—Lin28
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1307—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from adult fibroblasts
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- C12N2510/00—Genetically modified cells
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- Bioinformatics & Cheminformatics (AREA)
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- Animal Behavior & Ethology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
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- Transplantation (AREA)
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- Developmental Biology & Embryology (AREA)
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- Psychology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021121453A JP2021166553A (ja) | 2013-05-13 | 2021-07-26 | 合成メッセンジャーrnaによるヒト人工多能性幹細胞のフィーダーフリー誘導 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/893,166 US10155929B2 (en) | 2012-05-13 | 2013-05-13 | Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA |
| PCT/US2014/040362 WO2014190361A2 (en) | 2013-05-13 | 2014-05-30 | Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger rna |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019134561A Division JP2019170405A (ja) | 2019-07-22 | 2019-07-22 | 合成メッセンジャーrnaによるヒト人工多能性幹細胞のフィーダーフリー誘導 |
| JP2021121453A Division JP2021166553A (ja) | 2013-05-13 | 2021-07-26 | 合成メッセンジャーrnaによるヒト人工多能性幹細胞のフィーダーフリー誘導 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016521541A JP2016521541A (ja) | 2016-07-25 |
| JP2016521541A5 JP2016521541A5 (enExample) | 2017-05-25 |
| JP6971574B2 true JP6971574B2 (ja) | 2021-11-24 |
Family
ID=51939013
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016514171A Active JP6971574B2 (ja) | 2013-05-13 | 2014-05-30 | 合成メッセンジャーrnaによるヒト人工多能性幹細胞のフィーダーフリー誘導 |
| JP2021121453A Withdrawn JP2021166553A (ja) | 2013-05-13 | 2021-07-26 | 合成メッセンジャーrnaによるヒト人工多能性幹細胞のフィーダーフリー誘導 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021121453A Withdrawn JP2021166553A (ja) | 2013-05-13 | 2021-07-26 | 合成メッセンジャーrnaによるヒト人工多能性幹細胞のフィーダーフリー誘導 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10155929B2 (enExample) |
| EP (2) | EP3904504A1 (enExample) |
| JP (2) | JP6971574B2 (enExample) |
| CN (1) | CN105555949A (enExample) |
| HK (2) | HK1224335A1 (enExample) |
| MX (2) | MX2015015840A (enExample) |
| SG (2) | SG10202006695TA (enExample) |
| WO (1) | WO2014190361A2 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8497124B2 (en) | 2011-12-05 | 2013-07-30 | Factor Bioscience Inc. | Methods and products for reprogramming cells to a less differentiated state |
| DK3260140T3 (da) | 2011-12-05 | 2021-04-19 | Factor Bioscience Inc | Fremgangsmåder og produkter til transficering af celler |
| EP3561054B1 (en) * | 2012-05-13 | 2023-07-05 | Allele Biotechnology And Pharmaceuticals, Inc. | Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger rna |
| US10155929B2 (en) * | 2012-05-13 | 2018-12-18 | Allele Biotechnology & Pharmaceuticals, Inc. | Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA |
| US10119150B2 (en) | 2012-05-13 | 2018-11-06 | Allele Biotechnology & Pharmaceuticals, Inc. | Feeder-free Derivation of human-induced pluripotent stem cells with synthetic messenger RNA |
| CA2876868A1 (en) * | 2012-06-13 | 2013-12-19 | Stemgent, Inc. | Methods of preparing pluripotent stem cells |
| BR122019025681B1 (pt) | 2012-11-01 | 2023-04-18 | Factor Bioscience Inc | Método para inserir uma sequência de ácido nucleico em uma localização segura de um genoma de uma célula |
| WO2015117021A1 (en) | 2014-01-31 | 2015-08-06 | Factor Bioscience Inc. | Methods and products for nucleic acid production and delivery |
| CA2950582C (en) * | 2014-05-30 | 2020-09-22 | Allele Biotechnology And Pharmaceuticals, Inc. | Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger rna |
| EP3543339A1 (en) | 2015-02-13 | 2019-09-25 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| WO2019241569A1 (en) * | 2018-06-16 | 2019-12-19 | Luigi Warren | Reprogramming cells with synthetic messenger rna |
| CN105567642B (zh) * | 2016-02-01 | 2019-07-12 | 中国科学院生物物理研究所 | 一种着色性干皮病人多能干细胞的制备方法 |
| CN109803977B (zh) | 2016-08-17 | 2023-03-17 | 菲克特生物科学股份有限公司 | 核酸产品及其施用方法 |
| CA3043372A1 (en) | 2016-11-16 | 2018-05-24 | Allele Biotechnology & Pharmaceuticals, Inc. | Induction of pancreatic beta cells by stem cell differentiation with rna |
| EP3564362A4 (en) * | 2016-12-28 | 2020-07-08 | Kyoto Prefectural Public University Corporation | SKELETAL MUSCLE CELLS AND THEIR INDUCTION METHOD |
| CN107142244B (zh) * | 2017-07-03 | 2019-12-20 | 广州润虹医药科技股份有限公司 | 培养基及其用途与诱导多能干细胞向间充质干细胞转化的方法 |
| EP3652200A4 (en) | 2017-07-13 | 2021-04-28 | Allele Biotechnology And Pharmaceuticals, Inc. | INDUCTION OF NEURAL PROGENITOR CELLS, OLIGODENDROCYTE AND OLIGODENDROCYTE PROGENITOR CELLS BY DIFFERENTIATION OF STEM CELLS USING MARKET TRANSCRIPTION FACTORS |
| SG11202008839WA (en) * | 2018-03-13 | 2020-10-29 | Univ Leland Stanford Junior | Transient cellular reprogramming for reversal of cell aging |
| EP3969571A4 (en) | 2019-05-14 | 2023-05-24 | Aleph Farms Ltd. | AGGREGATES OF PLURIPOTENT CELLS AND THEIR USE |
| WO2021003462A1 (en) | 2019-07-03 | 2021-01-07 | Factor Bioscience Inc. | Cationic lipids and uses thereof |
| US10501404B1 (en) | 2019-07-30 | 2019-12-10 | Factor Bioscience Inc. | Cationic lipids and transfection methods |
| JP2022104813A (ja) | 2020-12-29 | 2022-07-11 | アイ ピース,インコーポレイテッド | リプログラミング因子を導入された細胞の培養方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260432A (en) | 1989-06-22 | 1993-11-09 | Sloan-Kettering Institute For Cancer Research | Human gamma retinoic acid receptor DNA |
| JP2008307007A (ja) * | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| SG160248A1 (en) * | 2008-09-18 | 2010-04-29 | Agency Science Tech & Res | Use of novel monoclonal antibodies targeting human embryonic stem cells to characterize and kill induced pluripotent stem cells |
| EP2881461A1 (en) | 2008-11-21 | 2015-06-10 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Reprogramming cells toward a pluripotent state |
| WO2010108126A2 (en) | 2009-03-19 | 2010-09-23 | Fate Therapeutics, Inc. | Reprogramming compositions and methods of using the same |
| WO2011016588A1 (en) * | 2009-08-07 | 2011-02-10 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| CN102190731B (zh) * | 2010-03-09 | 2016-01-27 | 中国科学院上海生命科学研究院 | 用人工转录因子诱导产生多能干细胞 |
| WO2011140397A2 (en) * | 2010-05-05 | 2011-11-10 | The Regents Of The University Of California Office Of The President | Stem cell defined media for xeno-free and feeder free conditions and uses thereof |
| WO2011142832A2 (en) | 2010-05-13 | 2011-11-17 | Whitehead Institute For Biomedical Research | Stem cells derived under low oxygen conditions |
| WO2012012708A1 (en) | 2010-07-22 | 2012-01-26 | Regents Of The University Of Minnesota | Induced pluripotent stem cells |
| WO2012144906A1 (en) * | 2011-04-22 | 2012-10-26 | Prosensa Technologies B.V. | New compounds for treating, delaying and/or preventing a human genetic disorder such as myotonic dystrophy type 1 (dm1) |
| US8497124B2 (en) | 2011-12-05 | 2013-07-30 | Factor Bioscience Inc. | Methods and products for reprogramming cells to a less differentiated state |
| CA2864702A1 (en) | 2012-02-22 | 2013-08-29 | Amgen Inc. | Autologous mammalian models derived from induced pluripotent stem cells and related methods |
| EP3561054B1 (en) | 2012-05-13 | 2023-07-05 | Allele Biotechnology And Pharmaceuticals, Inc. | Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger rna |
| US10155929B2 (en) | 2012-05-13 | 2018-12-18 | Allele Biotechnology & Pharmaceuticals, Inc. | Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA |
-
2013
- 2013-05-13 US US13/893,166 patent/US10155929B2/en active Active
-
2014
- 2014-05-30 CN CN201480033794.XA patent/CN105555949A/zh active Pending
- 2014-05-30 EP EP21154853.2A patent/EP3904504A1/en active Pending
- 2014-05-30 SG SG10202006695TA patent/SG10202006695TA/en unknown
- 2014-05-30 MX MX2015015840A patent/MX2015015840A/es unknown
- 2014-05-30 HK HK16112614.3A patent/HK1224335A1/zh unknown
- 2014-05-30 HK HK16110689.7A patent/HK1222675A1/zh unknown
- 2014-05-30 JP JP2016514171A patent/JP6971574B2/ja active Active
- 2014-05-30 WO PCT/US2014/040362 patent/WO2014190361A2/en not_active Ceased
- 2014-05-30 SG SG11201509368PA patent/SG11201509368PA/en unknown
- 2014-05-30 EP EP14801588.6A patent/EP2997130A4/en not_active Withdrawn
-
2015
- 2015-11-13 MX MX2021005715A patent/MX2021005715A/es unknown
-
2021
- 2021-07-26 JP JP2021121453A patent/JP2021166553A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016521541A (ja) | 2016-07-25 |
| WO2014190361A2 (en) | 2014-11-27 |
| MX2021005715A (es) | 2021-07-21 |
| HK1224335A1 (zh) | 2017-08-18 |
| WO2014190361A3 (en) | 2015-07-30 |
| SG10202006695TA (en) | 2020-08-28 |
| EP2997130A2 (en) | 2016-03-23 |
| EP3904504A1 (en) | 2021-11-03 |
| US20130302295A1 (en) | 2013-11-14 |
| HK1222675A1 (zh) | 2017-07-07 |
| CN105555949A (zh) | 2016-05-04 |
| US10155929B2 (en) | 2018-12-18 |
| EP2997130A4 (en) | 2017-03-01 |
| JP2021166553A (ja) | 2021-10-21 |
| SG11201509368PA (en) | 2015-12-30 |
| MX2015015840A (es) | 2016-08-11 |
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