HK1224335A1 - 使用合成信使rna无饲养层衍生人诱导多能干细胞 - Google Patents

使用合成信使rna无饲养层衍生人诱导多能干细胞 Download PDF

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Publication number
HK1224335A1
HK1224335A1 HK16112614.3A HK16112614A HK1224335A1 HK 1224335 A1 HK1224335 A1 HK 1224335A1 HK 16112614 A HK16112614 A HK 16112614A HK 1224335 A1 HK1224335 A1 HK 1224335A1
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cell
cells
reprogramming
mrna
feeder
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HK16112614.3A
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Chinese (zh)
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王繼武
王继武
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美国绿阳生物技术及医药公司
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Publication of HK1224335A1 publication Critical patent/HK1224335A1/zh

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A—HUMAN NECESSITIES
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1307—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from adult fibroblasts
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  • Medicinal Chemistry (AREA)
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  • Developmental Biology & Embryology (AREA)
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  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK16112614.3A 2013-05-13 2014-05-30 使用合成信使rna无饲养层衍生人诱导多能干细胞 HK1224335A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/893,166 US10155929B2 (en) 2012-05-13 2013-05-13 Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA
PCT/US2014/040362 WO2014190361A2 (en) 2013-05-13 2014-05-30 Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger rna

Publications (1)

Publication Number Publication Date
HK1224335A1 true HK1224335A1 (zh) 2017-08-18

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HK16112614.3A HK1224335A1 (zh) 2013-05-13 2014-05-30 使用合成信使rna无饲养层衍生人诱导多能干细胞
HK16110689.7A HK1222675A1 (zh) 2013-05-13 2014-05-30 使用合成信使rna无饲养层衍生人诱导多能干细胞

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HK16110689.7A HK1222675A1 (zh) 2013-05-13 2014-05-30 使用合成信使rna无饲养层衍生人诱导多能干细胞

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Country Link
US (1) US10155929B2 (enExample)
EP (2) EP3904504A1 (enExample)
JP (2) JP6971574B2 (enExample)
CN (1) CN105555949A (enExample)
HK (2) HK1224335A1 (enExample)
MX (2) MX2015015840A (enExample)
SG (2) SG10202006695TA (enExample)
WO (1) WO2014190361A2 (enExample)

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US8497124B2 (en) 2011-12-05 2013-07-30 Factor Bioscience Inc. Methods and products for reprogramming cells to a less differentiated state
DK3260140T3 (da) 2011-12-05 2021-04-19 Factor Bioscience Inc Fremgangsmåder og produkter til transficering af celler
EP3561054B1 (en) * 2012-05-13 2023-07-05 Allele Biotechnology And Pharmaceuticals, Inc. Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger rna
US10155929B2 (en) * 2012-05-13 2018-12-18 Allele Biotechnology & Pharmaceuticals, Inc. Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA
US10119150B2 (en) 2012-05-13 2018-11-06 Allele Biotechnology & Pharmaceuticals, Inc. Feeder-free Derivation of human-induced pluripotent stem cells with synthetic messenger RNA
CA2876868A1 (en) * 2012-06-13 2013-12-19 Stemgent, Inc. Methods of preparing pluripotent stem cells
BR122019025681B1 (pt) 2012-11-01 2023-04-18 Factor Bioscience Inc Método para inserir uma sequência de ácido nucleico em uma localização segura de um genoma de uma célula
WO2015117021A1 (en) 2014-01-31 2015-08-06 Factor Bioscience Inc. Methods and products for nucleic acid production and delivery
CA2950582C (en) * 2014-05-30 2020-09-22 Allele Biotechnology And Pharmaceuticals, Inc. Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger rna
EP3543339A1 (en) 2015-02-13 2019-09-25 Factor Bioscience Inc. Nucleic acid products and methods of administration thereof
WO2019241569A1 (en) * 2018-06-16 2019-12-19 Luigi Warren Reprogramming cells with synthetic messenger rna
CN105567642B (zh) * 2016-02-01 2019-07-12 中国科学院生物物理研究所 一种着色性干皮病人多能干细胞的制备方法
CN109803977B (zh) 2016-08-17 2023-03-17 菲克特生物科学股份有限公司 核酸产品及其施用方法
CA3043372A1 (en) 2016-11-16 2018-05-24 Allele Biotechnology & Pharmaceuticals, Inc. Induction of pancreatic beta cells by stem cell differentiation with rna
EP3564362A4 (en) * 2016-12-28 2020-07-08 Kyoto Prefectural Public University Corporation SKELETAL MUSCLE CELLS AND THEIR INDUCTION METHOD
CN107142244B (zh) * 2017-07-03 2019-12-20 广州润虹医药科技股份有限公司 培养基及其用途与诱导多能干细胞向间充质干细胞转化的方法
EP3652200A4 (en) 2017-07-13 2021-04-28 Allele Biotechnology And Pharmaceuticals, Inc. INDUCTION OF NEURAL PROGENITOR CELLS, OLIGODENDROCYTE AND OLIGODENDROCYTE PROGENITOR CELLS BY DIFFERENTIATION OF STEM CELLS USING MARKET TRANSCRIPTION FACTORS
SG11202008839WA (en) * 2018-03-13 2020-10-29 Univ Leland Stanford Junior Transient cellular reprogramming for reversal of cell aging
EP3969571A4 (en) 2019-05-14 2023-05-24 Aleph Farms Ltd. AGGREGATES OF PLURIPOTENT CELLS AND THEIR USE
WO2021003462A1 (en) 2019-07-03 2021-01-07 Factor Bioscience Inc. Cationic lipids and uses thereof
US10501404B1 (en) 2019-07-30 2019-12-10 Factor Bioscience Inc. Cationic lipids and transfection methods
JP2022104813A (ja) 2020-12-29 2022-07-11 アイ ピース，インコーポレイテッド リプログラミング因子を導入された細胞の培養方法

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US10155929B2 (en) 2012-05-13 2018-12-18 Allele Biotechnology & Pharmaceuticals, Inc. Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA

Also Published As

Publication number Publication date
JP2016521541A (ja) 2016-07-25
WO2014190361A2 (en) 2014-11-27
MX2021005715A (es) 2021-07-21
WO2014190361A3 (en) 2015-07-30
SG10202006695TA (en) 2020-08-28
EP2997130A2 (en) 2016-03-23
EP3904504A1 (en) 2021-11-03
US20130302295A1 (en) 2013-11-14
HK1222675A1 (zh) 2017-07-07
CN105555949A (zh) 2016-05-04
JP6971574B2 (ja) 2021-11-24
US10155929B2 (en) 2018-12-18
EP2997130A4 (en) 2017-03-01
JP2021166553A (ja) 2021-10-21
SG11201509368PA (en) 2015-12-30
MX2015015840A (es) 2016-08-11

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