JP6962920B2 - 卵巣癌の検出および治療のための組成物および方法 - Google Patents

卵巣癌の検出および治療のための組成物および方法 Download PDF

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JP6962920B2
JP6962920B2 JP2018534923A JP2018534923A JP6962920B2 JP 6962920 B2 JP6962920 B2 JP 6962920B2 JP 2018534923 A JP2018534923 A JP 2018534923A JP 2018534923 A JP2018534923 A JP 2018534923A JP 6962920 B2 JP6962920 B2 JP 6962920B2
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cdr
antibody
progastrin
amino acid
seq
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JP2019502923A5 (enExample
JP2019502923A (ja
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アレクサンドル、プリュール
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Progastrine et Cancers SARL
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Progastrine et Cancers SARL
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57449—Specifically defined cancers of ovaries
    • G01N33/57545—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/595—Gastrins; Cholecystokinins [CCK]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2018534923A 2015-12-31 2017-01-02 卵巣癌の検出および治療のための組成物および方法 Active JP6962920B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021167961A JP7279761B2 (ja) 2015-12-31 2021-10-13 卵巣癌の検出および治療のための組成物および方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP15307192.3 2015-12-31
EP15307192 2015-12-31
EP16305138.6 2016-02-05
EP16305138 2016-02-05
PCT/EP2017/050033 WO2017114972A1 (en) 2015-12-31 2017-01-02 Compositions and methods for detecting and treating ovarian cancer

Related Child Applications (1)

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JP2021167961A Division JP7279761B2 (ja) 2015-12-31 2021-10-13 卵巣癌の検出および治療のための組成物および方法

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JP2019502923A JP2019502923A (ja) 2019-01-31
JP2019502923A5 JP2019502923A5 (enExample) 2019-06-06
JP6962920B2 true JP6962920B2 (ja) 2021-11-05

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JP2021167961A Active JP7279761B2 (ja) 2015-12-31 2021-10-13 卵巣癌の検出および治療のための組成物および方法

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US (1) US11760808B2 (enExample)
EP (2) EP3397964B1 (enExample)
JP (2) JP6962920B2 (enExample)
KR (2) KR102507685B1 (enExample)
CN (1) CN108780091A (enExample)
AU (2) AU2017204682B2 (enExample)
BR (1) BR112018013271A2 (enExample)
CA (2) CA3194356C (enExample)
EA (1) EA037015B1 (enExample)
ES (2) ES2901602T3 (enExample)
PL (1) PL3397964T3 (enExample)
SG (1) SG11201805605TA (enExample)
WO (1) WO2017114972A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240018264A1 (en) * 2015-12-31 2024-01-18 Progastrine Et Cancers S.À R.L. Compositions and methods for detecting and treating ovarian cancer
EP3720879B1 (en) * 2017-12-05 2022-05-11 Progastrine et Cancers S.à r.l. Combination therapy between anti-progastrin antibody and immunotherapy to treat cancer
AU2018381046B2 (en) 2017-12-08 2025-10-02 Ecs-Biotracker Sàrl Radiolabeled progastrin in cancer diagnosis
TW201940881A (zh) 2018-01-26 2019-10-16 瑞士商Ｅｃｓ前胃泌激素公司 在癌症診斷中結合前胃泌激素檢測與其他癌症生物標記的技術
WO2019166499A1 (en) 2018-02-27 2019-09-06 Ecs-Progastrin Sa Progastrin as a biomarker for immunotherapy
JP7687224B2 (ja) * 2022-01-25 2025-06-03 株式会社三洋物産 遊技機
JP7687223B2 (ja) * 2022-01-25 2025-06-03 株式会社三洋物産 遊技機

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EP0519596B1 (en) 1991-05-17 2005-02-23 Merck & Co. Inc. A method for reducing the immunogenicity of antibody variable domains
WO1994004679A1 (en) 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
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JPH05244982A (ja) 1991-12-06 1993-09-24 Sumitomo Chem Co Ltd 擬人化ｂ−ｂ１０
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
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Also Published As

Publication number Publication date
EA201891529A1 (ru) 2019-01-31
WO2017114972A1 (en) 2017-07-06
EP3397964A1 (en) 2018-11-07
KR20180105647A (ko) 2018-09-28
JP2022009080A (ja) 2022-01-14
CA3194356A1 (en) 2017-07-06
AU2021250840A1 (en) 2021-11-04
KR102507685B1 (ko) 2023-03-08
EP3954999A1 (en) 2022-02-16
EP3397964B1 (en) 2021-09-29
AU2017204682B2 (en) 2021-07-29
SG11201805605TA (en) 2018-07-30
EP3954999B9 (en) 2025-03-12
EP3954999C0 (en) 2025-01-15
AU2021250840B2 (en) 2024-06-27
KR102428254B1 (ko) 2022-08-03
ES2901602T3 (es) 2022-03-23
AU2017204682A1 (en) 2018-07-19
CA3009751A1 (en) 2017-07-06
EA037015B1 (ru) 2021-01-27
KR20220100100A (ko) 2022-07-14
BR112018013271A2 (pt) 2018-12-11
CA3194356C (en) 2025-04-08
US11760808B2 (en) 2023-09-19
EP3954999B1 (en) 2025-01-15
JP2019502923A (ja) 2019-01-31
ES3015244T3 (en) 2025-04-30
CN108780091A (zh) 2018-11-09
PL3397964T3 (pl) 2022-02-07
JP7279761B2 (ja) 2023-05-23
US20190002582A1 (en) 2019-01-03

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