JP6959268B2 - 第ｘａ因子誘導体の調製 - Google Patents
第ｘａ因子誘導体の調製 Download PDFInfo
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- JP6959268B2 JP6959268B2 JP2018565888A JP2018565888A JP6959268B2 JP 6959268 B2 JP6959268 B2 JP 6959268B2 JP 2018565888 A JP2018565888 A JP 2018565888A JP 2018565888 A JP2018565888 A JP 2018565888A JP 6959268 B2 JP6959268 B2 JP 6959268B2
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| JP2023074627A JP2023086970A (ja) | 2016-06-17 | 2023-04-28 | 第ｘａ因子誘導体の調製 |
| JP2025166337A JP2026010692A (ja) | 2016-06-17 | 2025-10-02 | 第ｘａ因子誘導体の調製 |
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| PL3604510T3 (pl) * | 2009-03-30 | 2025-07-28 | Alexion Pharmaceuticals, Inc. | Antidota na inhibitory czynnika xa i sposoby ich stosowania |
| SG10201705189XA (en) * | 2013-01-24 | 2017-07-28 | Portola Pharm Inc | INHIBITION OF TISSUE FACTOR PATHWAY INHIBITOR WITH FACTOR Xa DERIVATIVES |
| JP6959268B2 (ja) * | 2016-06-17 | 2021-11-02 | ポートラ ファーマシューティカルズ， インコーポレイテッド | 第ｘａ因子誘導体の調製 |
| WO2019246094A1 (en) | 2018-06-19 | 2019-12-26 | Portola Pharmaceuticals, Inc. | Antidotes to factor xa inhibitors |
| KR102337683B1 (ko) * | 2018-09-21 | 2021-12-13 | 주식회사 녹십자 | 고효율 항-tfpi 항체 조성물 |
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| US5189019A (en) * | 1990-04-23 | 1993-02-23 | Merck & Co., Inc. | Antistasin derived anticoagulant protein |
| US5589571A (en) | 1994-10-28 | 1996-12-31 | Cor Therapeutics, Inc. | Process for production of inhibited forms of activated blood factors |
| JPH1066572A (ja) * | 1996-08-29 | 1998-03-10 | Showa Sangyo Co Ltd | 高純度の大豆トリプシンインヒビターの製造方法 |
| AU2001250783A1 (en) | 2000-02-29 | 2001-09-12 | Cor Therapeutics, Inc. | Benzamides and related inhibitors of factor xa |
| NZ592533A (en) | 2005-11-08 | 2012-08-31 | Millennium Pharm Inc | METHOD FOR THE PREPARATION OF N-(5-CHLORO-2-PYRIDINYL)-2-[[4-[(DIMETHYLAMINO) IMINOMETHYL] BENZOYL] AMINO]-5-METHOXY-BENZAMIDE, A FACTOR Xa INHIBITOR |
| KR102069498B1 (ko) * | 2007-09-28 | 2020-01-23 | 포톨라 파마슈티컬스, 인코포레이티드 | 인자 Ｘａ 저해제에 대한 안티도트 및 그것을 사용하는 방법 |
| EP2364165B1 (en) | 2008-11-14 | 2018-01-03 | Portola Pharmaceuticals, Inc. | Antidotes for factor xa inhibitors and methods of using the same in combination with blood coagulating agents |
| PL3604510T3 (pl) * | 2009-03-30 | 2025-07-28 | Alexion Pharmaceuticals, Inc. | Antidota na inhibitory czynnika xa i sposoby ich stosowania |
| PT2453910T (pt) * | 2009-07-15 | 2016-12-07 | Portola Pharm Inc | Formulação de dose unitária de antídoto contra inibidores de fator xa para uso na prevenção de sangramento |
| JP6261093B2 (ja) * | 2012-06-14 | 2018-01-17 | ポートラ ファーマシューティカルズ， インコーポレイテッド | 組み換え第Ｘａ因子誘導体の精製のための方法 |
| US20140346397A1 (en) | 2012-12-27 | 2014-11-27 | Portola Pharmaceuticals, Inc. | Compounds and methods for purification of serine proteases |
| SG10201705189XA (en) | 2013-01-24 | 2017-07-28 | Portola Pharm Inc | INHIBITION OF TISSUE FACTOR PATHWAY INHIBITOR WITH FACTOR Xa DERIVATIVES |
| MY173548A (en) * | 2013-09-24 | 2020-02-04 | Pfizer | Fxa variant compositions |
| KR20250150675A (ko) * | 2014-08-20 | 2025-10-20 | 포톨라 파마슈티컬스, 인코포레이티드 | 인자 xa 해독제용 동결건조된 제형 |
| JP6959268B2 (ja) * | 2016-06-17 | 2021-11-02 | ポートラ ファーマシューティカルズ， インコーポレイテッド | 第ｘａ因子誘導体の調製 |
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