JP6949012B2 - Ｂ型肝炎表面抗原に対する抗体及びその使用 - Google Patents

Ｂ型肝炎表面抗原に対する抗体及びその使用 Download PDF

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Publication number
JP6949012B2
JP6949012B2 JP2018518466A JP2018518466A JP6949012B2 JP 6949012 B2 JP6949012 B2 JP 6949012B2 JP 2018518466 A JP2018518466 A JP 2018518466A JP 2018518466 A JP2018518466 A JP 2018518466A JP 6949012 B2 JP6949012 B2 JP 6949012B2
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seq
antibody
antigen
binding fragment
hbv
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Japanese (ja)
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JP2018533937A5 (OSRAM
JP2018533937A (ja
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ルオ、ウエンシン
チョウ、ビン
チャン、ジュアン
ユアン、チェン
チャン、ティアンイン
チャン、ジュン
シァ、ニンシャオ
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Yang Sheng Tang Co Ltd
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Yang Sheng Tang Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/082—Hepadnaviridae, e.g. hepatitis B virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2018518466A 2015-10-09 2016-10-09 Ｂ型肝炎表面抗原に対する抗体及びその使用 Active JP6949012B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201510647977.7 2015-10-09
CN201510647977 2015-10-09
PCT/CN2016/101560 WO2017059813A1 (zh) 2015-10-09 2016-10-09 抗乙肝表面抗原的抗体及其用途

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020210762A Division JP2021063092A (ja) 2015-10-09 2020-12-18 Ｂ型肝炎表面抗原に対する抗体及びその使用

Publications (3)

Publication Number Publication Date
JP2018533937A JP2018533937A (ja) 2018-11-22
JP2018533937A5 JP2018533937A5 (OSRAM) 2019-01-10
JP6949012B2 true JP6949012B2 (ja) 2021-10-13

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Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018518466A Active JP6949012B2 (ja) 2015-10-09 2016-10-09 Ｂ型肝炎表面抗原に対する抗体及びその使用
JP2020210762A Withdrawn JP2021063092A (ja) 2015-10-09 2020-12-18 Ｂ型肝炎表面抗原に対する抗体及びその使用

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JP2020210762A Withdrawn JP2021063092A (ja) 2015-10-09 2020-12-18 Ｂ型肝炎表面抗原に対する抗体及びその使用

Country Status (10)

Country Link
US (1) US10689434B2 (OSRAM)
EP (1) EP3360896B1 (OSRAM)
JP (2) JP6949012B2 (OSRAM)
KR (1) KR102132604B1 (OSRAM)
CN (1) CN106565840B (OSRAM)
AU (1) AU2016334290B2 (OSRAM)
BR (1) BR112018007121A2 (OSRAM)
CA (1) CA3001231C (OSRAM)
ES (1) ES3041684T3 (OSRAM)
WO (1) WO2017059813A1 (OSRAM)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3001231C (en) * 2015-10-09 2022-07-12 Xiamen University Antibody against hepatitis b surface antigen and use thereof
US11932681B2 (en) 2018-05-31 2024-03-19 Novartis Ag Hepatitis B antibodies
NZ770866A (en) * 2018-05-31 2025-07-25 Daiichi Sankyo Co Ltd Anti-human tlr7 antibody
JP7454855B2 (ja) * 2018-12-21 2024-03-25 国立大学法人広島大学 抗ｐｒｅＳ１抗体およびその用途
WO2020233695A1 (zh) * 2019-05-23 2020-11-26 厦门大学 抗乙肝病毒新型抗体及其用途
CN111242107B (zh) * 2020-04-26 2021-03-09 北京外号信息技术有限公司 用于设置空间中的虚拟对象的方法和电子设备
WO2024148263A1 (en) * 2023-01-06 2024-07-11 Victorian Infectious Diseases Reference Laboratory Methods and compositions for antibody treatment of hepatitis b infection

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1322761A4 (en) 2000-10-02 2005-03-23 Korea Res Inst Of Bioscience HUMANIZED ANTIBODY AGAINST THE HEPATITE B VIRUS SURFACE ANTIGEN AND METHOD OF PREPARING THE SAME
CN1560081A (zh) * 2004-02-17 2005-01-05 大连帝恩生物工程有限公司 用能产生人IgGl重链－κ轻链小鼠作为制备人源化单克隆抗体和应用
US9567390B2 (en) * 2008-01-23 2017-02-14 Department Of Biotechnology Humanized high affinity recombinant antibody against Hepatitis B surface antigen
KR101072895B1 (ko) * 2009-12-24 2011-10-17 주식회사 녹십자 Ｂ형 간염 바이러스 표면 항원에 특이적으로 결합하는 인간 항체
CN102786592A (zh) * 2011-05-17 2012-11-21 傅阳心 Hbv特异性抗体
KR102106782B1 (ko) 2012-06-11 2020-05-07 시아먼 유니버시티 에이치비브이 감염 및 관련 질병의 치료를 위한 폴리펩타이드 및 항체
CA2878155C (en) * 2012-07-10 2019-01-08 Green Cross Corporation An antibody composition for prevention or treatment of mutant hepatitis b virus infection
SG10201806025TA (en) * 2014-01-16 2018-08-30 Mario Umberto Francesco Mondelli Neutralizing human monoclonal antibodies against hepatitis b virus surface antigen
CA3001231C (en) * 2015-10-09 2022-07-12 Xiamen University Antibody against hepatitis b surface antigen and use thereof

Also Published As

Publication number Publication date
CA3001231A1 (en) 2017-04-13
WO2017059813A1 (zh) 2017-04-13
JP2021063092A (ja) 2021-04-22
AU2016334290A1 (en) 2018-05-10
CN106565840A (zh) 2017-04-19
JP2018533937A (ja) 2018-11-22
CA3001231C (en) 2022-07-12
KR102132604B1 (ko) 2020-07-13
ES3041684T3 (en) 2025-11-13
US20190389939A1 (en) 2019-12-26
AU2016334290B2 (en) 2020-06-18
US10689434B2 (en) 2020-06-23
EP3360896A4 (en) 2019-08-28
BR112018007121A2 (pt) 2018-11-06
CN106565840B (zh) 2020-09-01
EP3360896B1 (en) 2025-07-23
EP3360896A1 (en) 2018-08-15
KR20180084045A (ko) 2018-07-24

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